Study shows booster shot after 6 to 12 months likely to provide best protection from COVID-19, Pfizer says

Francine Orr / Los Angeles Times via Getty Images

(NEW YORK) — Pfizer and BioNTech have released initial data from a study on booster shots for their COVID-19 vaccine, saying a third dose delivered about six months after the second shot has shown neutralization titers are five to 10 times higher than after two primary doses.

The companies said they expect to publish “more definitive data” soon and submit the Food and Drug Administration “in the coming weeks.”

Pfizer said real-world evidence from Israel showed a decrease in efficacy about six months after people were fully vaccinated.

“While protection against severe disease remained high across the full 6 months, the observed decline in efficacy against symptomatic disease over time and the continued emergence of variants are key factors driving our belief that a booster dose will likely be necessary to maintain highest levels of protection,” Pfizer said in a statement.

Additionally, the companies are working on materials with a plan to test a new vaccine construct based on the delta variant — with plans to start clinical trials in August.

“While we believe a third dose of BNT162b2 has the potential to preserve the highest levels protective efficacy against all currently known variants including Delta, we are remaining vigilant and are developing an updated version of the Pfizer-COVID-19 vaccine that uses a new construct based on the B.1.617.2 lineage, first identified in India and also known as the Delta variant,” the companies said in a statement.

“The companies are already producing clinical trial material and anticipate beginning clinical studies in August, subject to regulatory approvals,” Pfizer and BioNTech added.

Moderna, the maker of the only other authorized mRNA vaccine in the U.S., has made similar statements about the need for booster shots in the past.

“Booster shots will be needed as we believe the virus is not going away,” Moderna CEO Stephane Bancel said during a first-quarter earnings call to investors in early May.

It will be up to the FDA and the Centers for Disease Control and Prevention to determine if and when booster shots will be allowed, recommended and made available.

“Clearly, the pharmaceutical companies have an economic incentive, particularly the ones who have vaccines that are for profit,” Dr. Dan Barouch, director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, told ABC News in late May. “We want the decision to be made based on public health solely and [not] on economic incentives of the companies.”

ABC News’ Arielle Mitropoulos, Dr. Deepak Ramanathan and Sony Salzman contributed to this report.

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Conservatives distort Biden’s pledge to ‘knock on doors’ to get people vaccinated

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(WASHINGTON) — President Joe Biden’s push to enlist volunteers, including local doctors and pastors, to go “literally knocking on doors” to encourage vaccinations in some states sparked an outcry this week among conservatives, who mischaracterized the effort as the deployment of government agents to strong-arm reluctant Americans.

The blowback — from right-wing media and Republican politicians on Twitter — prompted a sharp response Thursday from the White House, which says any door-knocking efforts will be locally led by community volunteers.

“I would say, for those individuals, organizations that are feeding misinformation and trying to mischaracterize this type of ‘trusted messenger’ work, I believe you are doing a disservice to the country and to the doctors, the faith leaders, community leaders and others who are working to get people vaccinated, save lives, and help end this pandemic,” Biden’s COVID coordinator, Jeff Zients, said.

Earlier this week, after missing his own goal to ensure 70% of U.S. adults received at least shot by the Fourth of July, Biden called for a stepped-up vaccination strategy that would rely on volunteers like faith leaders, local medical professionals and community organizations to canvas neighborhoods.

He also promised to assign White House-coordinated “surge teams” to any states requesting help, including personnel to help track outbreaks, boost testing or tailor pro-vaccine messages to the public.

“We need to go to community-by-community, neighborhood-by-neighborhood and, often times, door-to-door, literally knocking on doors to get help to the remaining people protected from the virus,” Biden said.

The comment was swiftly picked up by conservative pundits and outlets suggesting that federal agents would soon be knocking on doors or mandating a vaccine.

“How about don’t knock on my door,” tweeted Rep. Dan Crenshaw, a Texas Republican. “You’re not my parents. You’re the government. Make the vaccine available, and let people be free to choose. Why is that concept so hard for the left?”

Ohio Rep. Jim Jordan tweeted: “The Biden Administration wants to knock on your door to see if you’re vaccinated. What’s next? Knocking on your door to see if you own a gun?”

The Biden administration has said repeatedly that the federal government won’t mandate vaccines and will leave it up to businesses and schools to decide.

“It’s up to every individual to decide whether they’re going to get vaccinated,” said White House press secretary Jen Psaki this week.

Still, that message was muddied Thursday when Health and Human Services Secretary Xavier Becerra told CNN in an interview that “it is absolutely the government’s business” to know who isn’t vaccinated because of the money spent on the effort. He later added: “You don’t have to answer the door but I hope you do.”

Becerra later tweeted that his comments were being taken “wildly out of context.”

“To be clear: government has no database tracking who is vaccinated,” Becerra said. “We’re encouraging people to step up to protect themselves, others by getting vaccinated. It’s the best way to save lives and end this pandemic.”

In Missouri — one of the first states to receive help from the federal “surge” teams that Biden promised — the Republican governor there tweeted that government “agents” going door-to-door aren’t welcome.

“I have directed our health department to let the federal government know that sending government employees or agents door-to-door to compel vaccination would NOT be an effective OR a welcome strategy in Missouri!”

But according to an administration official who spoke on condition of anonymity, federal door knockers were never planned. At the request of the state’s health department, the Centers for Disease Control and Prevention deployed an epidemiologist to Missouri on Monday to help with genetic sequencing and data analysis through Aug. 6.

Another CDC official – a “risk communication specialist” – was tasked to provide remote support for one month to the Missouri Chief Bureau of Immunizations to help address local vaccine hesitancy and drive up vaccination numbers.

In a statement, the Missouri health department said it hoped more support was on its way.

“We are looking forward to collaborating with them and learning more about how the Delta variant is impacting Missouri, specifically southwest Missouri initially,” the department said in a statement.

“More team members will be added in the coming weeks, both remotely and in person, to assist with data and research, vaccine uptake strategies and outreach,” the department added.

ABC producer Arielle Mitropoulos and Sasha Pezenik contributed to this report.

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Millions under flash flood watches as Tropical Storm Elsa moves up East Coast

ABC News

(NEW YORK) — Tropical Storm Elsa is delivering heavy rain as it moves up the East Coast, with more than 50 million Americans under flash flood watches over the next 24 hours.

The storm is moving northeast at 20 mph, with the center about 25 miles southwest of Raleigh, North Carolina, as of Thursday afternoon. North Carolina residents saw heavy rain and wind gusts this afternoon that extended into southeastern Virginia, with maximum sustained winds at 45 mph.

There have been four reported tornadoes in three states thanks to Elsa, with Florida, Georgia and South Carolina all reporting damage.A tornado watch has been extended into southeastern Virginia and southern Maryland into Thursday evening.
 
 

Elsa is forecast to hug the Northeast coastline as it heads toward Nova Scotia, with some strengthening possible over the next 24 hours.

Heavy rain and gusty winds are expected in parts of Virginia and Maryland, and later in Delaware as it gets closer to Friday. The storm is forecast to hit Philadelphia and New York City early Friday, with heavy rain likely affecting commutes.

By late morning Friday, conditions likely will shift into New England and last into the afternoon and evening, before heading out of Maine Friday night.

Through Friday, a large swath of the East Coast is forecast to receive 2 to 4 inches of rain. The highest totals are likely along and east of Interstate-95 up across the mid-Atlantic. Up to 6 inches of rain is possible in parts of New York, Connecticut and Massachusetts.

Unrelated to Elsa, a severe thunderstorm watch has been issued for parts of the Northeast, from Pennsylvania to Connecticut, and remains in effect into Thursday evening.

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Darius Rucker’s legendary rock group Hootie & the Blowfish heads to Mexico for ‘Hootiefest’

Todd & Chris Owyoung

Hootie & the Blowfish are here to help you stoke your ’90s nostalgia and get a tan at the same time.

Darius Rucker‘s iconic rock group is hosting HootieFest: The Big Splash, a “destination concert vacation event” that will take place at Moon Palace in Cancún, Mexico, from January 26 to January 29.  The four-day event will include three headlining performances from Hootie on the beach, as well as daytime entertainment and nightly concerts by Barenaked Ladies, Toad the West Sprocket, Spin Doctors, Better than Ezra, Sister Hazel, Blues Traveler and Toadies.

After their 2019 Group Therapy tour with the Barenaked Ladies, Hootie & the Blowfish’s members just can’t help but keep the party going.

“We were blown away by the response from fans during our last tour,” Darius says. “It was so special to be back on stage together and to know that people still love the music as much as we do. What better way to keep that celebration going than in Mexico!?”

Packages including accommodations, concert access, transportation and more go on sale Thursday, July 15, at 1 p.m. ET  A 24-hour pre-sale starts Wednesday a 1 p.m. ET. For more information, visit Hootiefest.com.

In his solo country career, meanwhile, Darius scored his ninth number-one hit this year with “Beers & Sunshine.” His current single, “My Masterpiece,” is climbing the charts.

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Fender announces signature Kurt Cobain Jag-Stang guitar to celebrate 30th anniversary of ‘Nevermind’

Courtesy of Fender

Fender has announced the signature Kurt Cobain Jag-Stang guitar to celebrate the 30th anniversary of Nirvana‘s iconic 1991 album, Nevermind.

As its name suggests, the Jag-Stang is a combination of two popular Fender models: the Mustang and the Jaguar. Cobain used both guitars throughout his career before coming to Fender in 1993 to create the first Jag-Stang, featuring his favorite elements of both instruments.

The 2021 Jag-Stang replicates the specs of Cobain’s original model and comes in two colors: Fiesta Red and Sonic Blue. It’ll be available this October for $1,249.99.

For more info, visit Fender.com.

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Here’s how you can get Alicia Keys to personally serenade you on your birthday

Courtesy American Greetings

Alicia Keys has teamed with American Greetings for a series of music video greetings that feature the Grammy-winning star singing a personalized message just for you — as long as your name isn’t something really, really weird.

Part of American Greetings’ “Smashups Music Video Series,” the Alicia Keys “Your Day” ecard shows Alicia performing a version of her song “New Day,” from her 2012 album Girl on Fire.  The video can be personalized so Alicia literally dedicates the song to you — that is, if your name is one of 1,000 names on the drop-down list, which starts with “Aalam” and ends with “Zooey.” 

The card can also be personalized so that Alicia dedicates the song to an endearment, such as “Babe,” “Sweetie” or “Honey,” or to a loved one’s title, like Grandpa, Dad, Mom, Buddy, Coach, Nana and more. Sadly, those celebs who named their kids “Bear” or “Apple” or “Lyra” are out of luck.

“I always wished I could celebrate birthdays and other special moments with each and every one of the people that love and support me and my music and I’m so excited that now I’m able to do just that with these incredibly special SmashUps,” Alicia says in a statement. “You are going to feel it and LOVE it!”

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The Go-Go’s releasing pink-vinyl 40th anniversary version of ‘Beauty and the Beat’ in September

Capitol Records/UMe

The Go-Go’s released their classic debut album, Beauty and the Beat, 40 years ago today, and in conjunction with that milestone anniversary, the famed all-female band has announced plans to issue a special limited-edition pink-vinyl version of the record on September 10.

The reissue features new cover art: a previously unseen image from the same photo shoot that produced Beauty and the Beat‘s original cover, showing the group wearing bath towels and face cream.

Each copy of the Beauty and the Beat vinyl reissue will be numbered, and the LP is available exclusively at the group’s official store, at uDiscoverMusic.com and at The SoundofVinyl.com. You can pre-order the album now.

Released on July 8, 1981, Beauty and the Beat spent six consecutive weeks at #1 on the Billboard 200 in March and April of the following year. To date, it’s the only Billboard 200 number-one album by an all-female band who wrote their own songs and played their own instruments.

Beauty and the Beat featured two of the group’s biggest hits: “Our Lips Are Sealed,” which peaked at #20 on the Billboard Hot 100, and “We Got the Beat,” which reached #2.

Earlier this year, The Go-Go’s were chosen for induction into the Rock & Roll Hall of Fame, and the band will be welcomed into the hallowed institution at an October 30 ceremony in Cleveland.

The group also recently lined up a five-date series of late-2021 and early-2022 concerts, running from a December 28 show in San Francisco through January 3 in San Diego.  Those dates also include a December 31-January 1 stand in Las Vegas.

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Naya Rivera’s family reflects on her life and legacy on the one-year anniversary of her death

ABC’s “Good Morning America”

Naya Rivera‘s family is honoring her memory, and who she was as a daughter, sister, mother and artist, on the one-year anniversary of the Glee star’s tragic death.

Naya’s mother, Yolanda Previtire, told ABC News’ Juju Chang and Good Morning America the sadness associated with losing her daughter often becomes too much for her and her family to deal with.

“Sometimes we’re afraid of the sorrow being so heavy that we’re afraid for our own self, ’cause this is hard. There are no words to describe what we’re going through,” Yolanda said. “All we know is we have each other.”

Yolanda also noted that the family is in therapy to help with the shared trauma.

Naya’s younger sister, Nickayla Rivera, told GMA that what keeps them going is “taking that one day at a time and living it to the fullest, loving each other to the fullest, and not regretting anything. Because I know if we could go back, we’d hug a little bit harder.”

Yolanda added, “I feel Naya’s energy constantly telling me, ‘Mom, be happy. Don’t cry. I’m OK. Go get Josey. Have fun.’ And I feel that it’s coming from her.”

Naya Rivera went missing on July 8, 2020, at California’s Lake Piru, where she’d spent the day with her son, Josey Hollis Dorsey, who was four at the time and will be six in September. After failing to return the boat they had rented for the day, a search began for Naya and Josey. The child was found, wearing a life jacket, alone in the vessel, with Naya nowhere in sight.

Naya’s body was found five days after she went missing. The actress’ death was ruled an accidental drowning and she was laid to rest on July 24, 2020. She was 33.

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Jason Derulo says he “spoke” his baby son “into existence”

Martin Depict

Jason Derulo and his girlfriend, Jena Frumes, welcomed their first child, Jason King, on May 8. Jason says he always knew that they’d have a boy, because he literally willed it to happen.

“My brother has girls, and my sister has a girl, so I knew we needed a boy to carry on the name, literally. We needed to have a boy because the Derulo name was out,” Jason tells People magazine. “I spoke him into existence.”

But then Jason went the extra step of naming the baby after himself, explaining, “I wanted my name to continue to thrive, and I also thought that it would bring me closer to him.”

As for whether little Jason will follow in his dad’s footsteps, the “Savage Love” singer tells People, “He seems to really adore music already…it’s the only thing that keeps him calm. He’ll be going crazy one minute and then you start playing some music and he’s okay.”

In fact, Jason says the baby has inspired him to start courting a new audience.  “I was actually thinking of making some kiddie music for him…He’ll be the first critic,” says Jason of the baby. “If he likes it, then I guess the other kids will like it.”

But Jason’s dreams for his son’s future have more to do with the gym than the recording studio.

“I want him to have a foundation in health and fitness,” he explains. “I want to see what he gravitates towards, but I want to expose him to a lot so that he can choose his own way. But for me, it is a must that he does sports, for health reasons.”

 

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Cancer death rates fall, with a few exceptions

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(NEW YORK) — Cancer death rates continue to decline, with decreases in melanoma and lung cancer death rates leading that trend, according to a new report.

The report, published by the Journal of the National Cancer Institute Thursday, includes data from 2001 to 2018, meaning it does not reflect cancer incidence or deaths rates during the COVID-19 pandemic.

The decline in cancer death rates held true for both men and women of all racial and ethnic groups. The report showed a decrease in death rates among 11 of the 19 most common cancers in men and 14 of the 20 most common cancers in women. That overall decline translates into an average 2.2% cancer death rate decrease per year for men and an average 1.7% decrease per year for women.

Experts attributed the decline in deaths to reduced smoking rates and targeted cancer treatments.

“The continued decline in cancer death rates should be gratifying to the cancer research community, as evidence that scientific advances over several decades are making a real difference in outcomes at the population level,” Dr. Norman Sharpless, director of the National Cancer Institute, one of the groups that collaborated on the report, said in a statement.

Despite those gains, death rates for a few types of cancers, including uterus, brain, nervous system and pancreatic cancers, increased.

Additionally, cancer incidence rates among women, children, adolescents and young adults rose between 2014 and 2018, the report found. The most common cancer among adolescents and young adults ages 15 to 39 was female breast cancer. Among children younger than 15, the most common cancers were leukemia, lymphoma and brain and nervous system cancers. Although the incidence of cancer is increasing among women, in general, cancer incidence rates are higher for men.

“I believe we could achieve even further improvements if we address obesity, which has the potential to overtake tobacco use to become the leading modifiable factor associated with cancer,” Sharpless added.

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