Hearing underway on Karmelo Anthony’s bid for new trial in track meet stabbing

Hearing underway on Karmelo Anthony’s bid for new trial in track meet stabbing
Hearing underway on Karmelo Anthony’s bid for new trial in track meet stabbing
Austin Metcalf in a family provided photo. (Metcalf Family)

(FRISCO, Texas) — A Texas judge is hearing arguments Thursday on whether Karmelo Anthony should get a new trial, two months after a jury convicted and sentenced him to 35 years in prison for fatally stabbing a fellow student at a high school track meet.

The hearing comes a day after the Collin County judge who presided over the murder trial was removed from further proceedings in the case.

Prosecutors called the deadly stabbing “unjustified” and “plain and simple murder,” while the defense argued that Anthony acted in self-defense when he stabbed 17-year-old Austin Metcalf at a track meet in Frisco in April 2025.

After hearing four days of testimony, a Collin County jury found Anthony, 19, guilty of murder following three hours of deliberation on June 9. The same jury sentenced him to 35 years in prison after several more hours of deliberation.

Anthony’s attorneys claimed in a motion seeking a new trial that the teen was “coerced” into waiving his right to testify, stemming from a purported dispute between defense attorneys and prosecutors about whether his testimony would be covered by an agreement limiting some character evidence in the trial. Defense attorneys alleged this denied him a “complete defense.”

The defense also alleged that Collin County Judge John Roach improperly instructed the jury and that his courtroom restrictions, which limited public access to the proceedings, denied Anthony a fair trial.

In a statement to ABC Dallas affiliate WFAA ahead of this week’s hearings, Collin County First Assistant District Attorney Bill Wirskye said Anthony’s new, post-trial attorneys “filed a motion containing several inaccurate characterizations of the trial proceedings.”

“I and the entire prosecution team conducted this trial ethically and in full compliance with the Court’s ruling and any agreements with defense counsel,” Wirskye added.

In opening remarks during Thursday’s hearing, defense attorney Russell Wilson said Anthony decided not to testify because he believed the prosecution would not adhere to the agreement not to question him about his past behavior, beyond what happened during the confrontation at the track meet, WFAA reported.

Wirskye, meanwhile, said he offered the agreement to “stay away from historical character and stick to the facts — what happened under the tent” in order to “keep the peace” amid what he said was intense public vitriol over the case that led to threats against both sides, WFAA reported. He said the trial defense attorneys agreed to it, and that the “agreement was held.”

Wirskye also pushed back on defense claims that Anthony had insufficient time to decide whether to testify and noted that prosecutors wanted him to take the stand, saying, “There’s nothing better in my business than a testifying defendant,” WFAA reported.

The hearing is ongoing, with the defense so far calling Derrick Jackson, the former Collin County public information officer, to discuss the courtroom protocols, and Mike Howard, one of Anthony’s trial attorneys.

A new judge is presiding over Thursday’s hearing, after Judge Sid Harle granted the defense’s motion to recuse Roach from any further matters in the Anthony case.

In his order issued Wednesday, Harle wrote that there were grounds for recusal “in that the evidence adduced at the hearing is such that the respondent judge’s impartiality might reasonably be questioned.”

Retired Kaufman County District Judge Michael Chitty has been assigned to oversee the case.

In the defense motion seeking to recuse the trial judge from the post-trial proceedings, Anthony’s attorneys questioned both Roach’s impartiality in the case and his courtroom restrictions.

The motion cited what it called “problematic comments” Roach made during an interview following the verdict, in which it said the judge “endorsed the jury’s guilty verdict” and defended his courtroom restrictions. It also pointed to a public letter Roach released following the trial, in which he stated that those who worked on the case “contributed to ensuring the process was conducted fairly.”

Anthony’s attorneys said Wednesday that they are “pleased” with Harle’s decision to recuse Roach and “look forward to presenting the merits of Karmelo’s motion for a new trial to a fair and independent judge.”

Ahead of the high-profile trial, Roach imposed a gag order and barred any electronics from the courtroom during the proceedings due to the attention the case had garnered.

“Due to the significant public and media interest in this case, the Court finds that specific procedures are necessary to ensure the Defendant’s right to a fair and impartial trial, the orderly administration of justice, the safety and security of all participants, and reasonable public access consistent with constitutional requirements,” Roach wrote in a May order.

On Wednesday, Chitty ordered that the trial procedures will remain in effect at this time for future proceedings in the case.

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Woman arrested for allegedly plotting New York state Capitol attack

Woman arrested for allegedly plotting New York state Capitol attack
Woman arrested for allegedly plotting New York state Capitol attack
The New York State Capitol Building in Albany. (Demerzel21/Getty Images)

(NEW YORK) — The FBI arrested a woman who they allege was plotting to attack the New York State Capitol building in Albany.

The FBI alleged in a criminal complaint Thursday that Jessica Bowie, 35, pledged allegiance to ISIS in online communications and began planning the attack in July.

The suspect converted to Islam about five years ago and in messages with unidentified users pledged support to ISIS, the criminal complaint said.

Bowie had allegedly discussed her plans with FBI informants and spent weeks doing surveillance of the Capitol, including taking pictures from various vantage points, including an “observation hall nearby,” the criminal complaint said.

She allegedly bought bomb materials from a hardware store on Aug. 5 and plotted with the informants for the next two weeks, according to the complaint.

The informants allegedly met with Bowie on Wednesday and provided her with an inert explosive device and an inert handgun along with instructions on how to detonate the explosive, the complaint said.

The FBI soon arrested her, the complaint said.

Upon being interviewed by FBI agents she allegedly said, “There’s no helping me, you guys know enough, there’s no helping me, I’m … going to prison for the rest of my life,” according to the complaint.

“Material support is up to 20 years in prison, I already Googled it before, I know I’m going to jail,” she allegedly said.

Attorney information for the suspect was not immediately available.

This is a developing story.

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FBI seizes former Rep. Swallwell’s phone, devices as part of criminal probe, sources said

FBI seizes former Rep. Swallwell’s phone, devices as part of criminal probe, sources said
FBI seizes former Rep. Swallwell’s phone, devices as part of criminal probe, sources said
Former U.S. Rep. Eric Swalwell departs the U.S. Capitol Building on March 5, 2026, in Washington, D.C. (Anna Moneymaker/Getty Images)

(WASHINGTON) — The FBI seized former Democratic Rep. Eric Swalwell’s electronic devices as part of an ongoing criminal probe, according to sources familiar with the situation. 

Swalwell was served with a search warrant for his cellphone and other electronic devices while he was at San Francisco International Airport on Saturday night, according to sources, and agents served a search warrant at his Washington, D.C., home on Sunday. 

This is a developing story. Please check back for updates.

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Trump shows off multimillion-dollar White House helipad and adds his signature

Trump shows off multimillion-dollar White House helipad and adds his signature
Trump shows off multimillion-dollar White House helipad and adds his signature
President Donald Trump signs a piece of stone at the construction site of a helipad on the South Lawn of the White House in Washington, Aug. 19, 2026. (Alex Wong/Getty Images)

(WASHINGTON) — President Donald Trump on Wednesday signed his name on one of the slabs of a new multimillion-dollar granite helipad being built on the White House South Lawn as he showcased the ongoing construction project for the first time.

“It’s very exciting, very exciting, and I think it will be here for a long time,” Trump told reporters as he gave them a tour and touted the project, which will feature the U.S. seal.  

But questions are mounting about who is paying for the project and if taxpayers might be on the hook.

Trump announced the helipad in July from the Oval Office, and said that Sikorsky, the manufacturer of the Marine One fleet that carries the president, would pay for the build.

“They are paying for the cost of it. It’s about $5 or $6 million. They’re paying the full cost,” Trump said at the time.

On Wednesday Trump reiterated that Sikorsky was footing much of the bill with additional “donations from numerous people, including me.”

A spokesperson for Lockheed Martin, Sikorsky’s parent company, told ABC News in a statement last month that its contribution was “made to the National Park Service.”

They added that their work with the administration was being “guided by rigorous ethics and compliance standards.”

Trump said crews were working nearly around the clock to bring the project in for a landing, starting as early as six in the morning and wrapping at midnight.

In addition to landing Marine One, the helipad would be used for when foreign dignitaries come for state visits and as a cocktail space ahead of events at the ballroom he’s constructing. He has in the past said it could also be used for news conferences.

The president said his signature, and that of those leading the project, will be on the back of the head of the eagle, which is part of the U.S. seal, and would not be visible once the project is complete.

ABC News has asked the White House Historical Association whether there are any past instances of a president inscribing their own name on a project on the grounds. 

The president has said the landing zone is being built to allow newer Marine One helicopters that ferry the president to make trips to the White House.

“This is a helipad at the highest level. It can land any helicopter in the world, no matter how big, no matter how powerful, no matter how strong,” he said.

Lockheed Martin delivered a new fleet of Sikorsky helicopters to the Air Force in 2024, but the White House has had to keep using the older fleet for South Lawn departures and arrivals because they burn the grass. The newer helicopters have been used at other locations. 

A construction worker told the president that the helipad could be completed by “the 21st,” though it was not clear if that was of August or September. Trump is slated to welcome Chinese President Xi Jinping on Sept. 24.

“Oh, so we might make it for President Xi? That would be great,” Trump said. He later added, “Not imperative, but it would be very nice to have it done.”

He also admitted that work was delayed for a week after he asked for the helipad to be raised to account for a slope in the lawn.

“Sorry to take an extra week and a half, but lifting it up was one of the best things we’ve ever done, right? Trump said to the construction workers standing around him.

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‘Massive’ Russian missile strike on Kyiv kills at least 15 people, Zelenskyy says

‘Massive’ Russian missile strike on Kyiv kills at least 15 people, Zelenskyy says
‘Massive’ Russian missile strike on Kyiv kills at least 15 people, Zelenskyy says
People inspect the aftermath of a Russian missile strike on Aug. 20, 2026, in Kyiv, Ukraine. Apartment blocks and warehouses were hit across the city overnight following a large barrage of missiles, with a children’s hospital and school also damaged. (Diego Fedele/Getty Images)

LONDON — A “massive” Russian missile and drone attack on Kyiv on Wednesday night killed at least 15 people and injured more than 40 others, Ukrainian President Volodymyr Zelenskyy said in a post to social media on Thursday.

“Throughout the night, our emergency services have been working at the sites of Russian strikes,” Zelenskyy wrote. “The attack was massive — the Russians prepared for a long time and combined different types of ballistic missiles, cruise missiles, and drones to inflict as much damage as possible on civilian infrastructure.”

Ukraine’s air force said Russia launched an unspecified number of ballistic missiles into the country overnight as well as 46 cruise or air-to-ground missiles of various types. Russia also launched 168 drones, the air force said.

“The main direction of the attack was the Kyiv region,” the air force wrote in a post to Telegram. It added that 41 cruise missiles of various types and 145 drones were shot down or otherwise suppressed, with munitions reported impacting across 28 locations.

The air force did not say whether any ballistic missiles were shot down. Earlier this month, the air force stopped publishing the number of ballistic missiles fired or intercepted in Russia’s nightly barrages.

Around the capital, Zelenskyy said that residential buildings, a children’s hospital and school were among the sites damaged. The president also reported overnight Russian attacks in the southern Odesa and northern Chernihiv regions.

Kyiv Mayor Vitali Klitschko said in posts to Telegram that damage was reported in the Sviatoshynskyi, Solomianskyi and Darnitskyi areas of the city, including fires at warehouses and residential buildings.

Recent months have seen an expansion of Russian missile attacks all across Ukraine, as officials in Kyiv warn that Ukrainian stocks of anti-missile interceptor munitions are dangerously low and, in some cases, exhausted.

Ukraine is working on its own ballistic missile interceptor program — the FREYJA — but officials in Kyiv have said they do not expect the weapon to be operational until 2027.

Zelenskyy on Thursday again appealed to foreign partners to route more ammunition to Kyiv. “Unfortunately, while Moscow is investing in ballistics and escalation, there isn’t always the necessary response from the world to such attacks,” he wrote.

“As long as Ukraine lacks sufficient anti-ballistic defenses, Russia will not seriously consider peace. We are doing everything we can to ensure protection, and work on the FREYJA program continues every day. However, interceptors for ‘Patriot’ systems are not yet available, and they are needed every day,” Zelenskyy wrote.

In a later post, the Ukrainian leader said that the country’s defense against ballistic missiles is “entirely dependent on the supply of missiles for ‘Patriot’ systems to Ukraine, and therefore, it depends on our partners.”

“We cannot simply stand by idly and watch as the Russians destroy lives with ballistic missiles. Ukrainian soldiers can operate effectively when the courage and professionalism of our people are supported by the appropriate assistance from our partners,” Zelenskyy added.

Ukrainian Foreign Minister Andrii Sybiha reported a “horrible and sleepless night in Kyiv,” in a post to X. “This was one of the most brutal Russian attacks to date, with ballistic missiles raining down on our capital one after another,” he wrote.

Russia’s Defense Ministry described the overnight attack as having targeted “military industrial enterprises, a transport and logistics hub and warehouses in Kyiv and the Kyiv region.”

The Defense Ministry also said that it shot down at least 726 Ukrainian drones over 18 Russian regions plus Crimea, the Sea of Azov and the Black Sea. At least 28 drones were shot down over the Moscow region, Moscow Mayor Sergey Sobyanin said on Telegram.

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Hearing on Karmelo Anthony’s bid for new trial in track meet stabbing set for Thursday

Hearing underway on Karmelo Anthony’s bid for new trial in track meet stabbing
Hearing underway on Karmelo Anthony’s bid for new trial in track meet stabbing
Austin Metcalf in a family provided photo. (Metcalf Family)

(FRISCO, Texas) — A Texas judge is set to hear arguments Thursday on whether Karmelo Anthony should get a new trial, two months after a jury convicted and sentenced him to 35 years in prison for fatally stabbing a fellow student at a high school track meet.

The hearing comes a day after the Collin County judge who presided over the murder trial was removed from further proceedings in the case.

Prosecutors called the deadly stabbing “unjustified” and “plain and simple murder,” while the defense argued that Anthony acted in self-defense when he stabbed 17-year-old Austin Metcalf at a track meet in Frisco in April 2025.

After hearing four days of testimony, a Collin County jury found Anthony, 19, guilty of murder following three hours of deliberation on June 9. The same jury sentenced him to 35 years in prison after several more hours of deliberation.

Anthony’s attorneys claimed in a motion seeking a new trial that the teen was “coerced” into waiving his right to testify, stemming from a purported dispute between defense attorneys and prosecutors about whether his testimony would be covered by an agreement limiting some character evidence in the trial. Defense attorneys alleged this denied him a “complete defense.”

The defense also alleged that Collin County Judge John Roach improperly instructed the jury and that his courtroom restrictions, which limited public access to the proceedings, denied Anthony a fair trial.

In a statement to ABC Dallas affiliate WFAA ahead of this week’s hearings, Collin County First Assistant District Attorney Bill Wirskye said Anthony’s new attorneys “filed a motion containing several inaccurate characterizations of the trial proceedings.”

“I and the entire prosecution team conducted this trial ethically and in full compliance with the Court’s ruling and any agreements with defense counsel,” Wirskye added.

A new judge will preside over Thursday’s hearing, after Judge Sid Harle granted the defense’s motion to recuse Roach from any further matters in the Anthony case.

In his order issued Wednesday, Harle wrote that there were grounds for recusal “in that the evidence adduced at the hearing is such that the respondent judge’s impartiality might reasonably be questioned.”

Retired Kaufman County District Judge Michael Chitty has been assigned to oversee the case.

In the defense motion seeking to recuse the trial judge from the post-trial proceedings, Anthony’s attorneys questioned both Roach’s impartiality in the case and his courtroom restrictions.

The motion cited what it called “problematic comments” Roach made during an interview following the verdict, in which it said the judge “endorsed the jury’s guilty verdict” and defended his courtroom restrictions. It also pointed to a public letter Roach released following the trial, in which he stated that those who worked on the case “contributed to ensuring the process was conducted fairly.”

Anthony’s attorneys said Wednesday that they are “pleased” with Harle’s decision to recuse Roach and “look forward to presenting the merits of Karmelo’s motion for a new trial to a fair and independent judge.”

Ahead of the high-profile trial, Roach imposed a gag order and barred any electronics from the courtroom during the proceedings due to the attention the case had garnered.

“Due to the significant public and media interest in this case, the Court finds that specific procedures are necessary to ensure the Defendant’s right to a fair and impartial trial, the orderly administration of justice, the safety and security of all participants, and reasonable public access consistent with constitutional requirements,” Roach wrote in a May order.

On Wednesday, Chitty ordered that the trial procedures will remain in effect at this time for future proceedings in the case. 

Copyright © 2026, ABC Audio. All rights reserved.

Pregnant woman has been held for weeks following immigration lawyer scam, family says

Pregnant woman has been held for weeks following immigration lawyer scam, family says
Pregnant woman has been held for weeks following immigration lawyer scam, family says
Kelly Ocampo believed her sister had been granted bond to be released from ICE detention. (Kelly Ocampo)

(DILLEY, Texas.) — Last month, Kelly Ocampo believed she received good news: Her 21-year-old pregnant sister had finally been granted bond and was going to be released from the family immigration detention center in Dilley, Texas.

The letter she received from a lawyer to whom she had paid more than $3,000 was written on U.S. Immigration and Customs Enforcement letterhead and stated that the ICE bond for Maria Alejandra Gomez-Quiroz was approved.

“This notice confirms that the immigration bond ordered by the Immigration Court has been successfully paid through an official payment method authorized by the U.S. Department of Homeland Security (DHS),” the letter stated.

When Ocampo received the letter, her sister had been in detention for a few weeks. But now, a month after she believed the bond was approved, her sister — who is five months pregnant — is still in federal immigration custody.

“It was a scam,” Ocampo told ABC News.

Ocampo believes she was scammed by an individual posing as an immigration attorney, and said her sister has now been detained for over 40 days. Ocampo and her family spent all their savings on the alleged lawyer to try to get her sister released, she said.

ABC News reached out to the person Ocampo says claimed to be a lawyer, but did not receive a response.

Ocampo told ABC News that her sister and partner were fleeing violent guerrillas in Colombia and were planning on applying for asylum in the U.S.

Gomez-Quiroz was arrested by U.S. Border Patrol at the border in June.

She is one of at least 500 people detained at Dilley and one of four pregnant women being held there as part of the Trump administration’s ongoing immigration crackdown, according to lawmakers.

Her detention comes as a federal district judge in California has ordered the appointment of a special master and independent monitor to examine “time in custody” at the Dilley facility to ensure that the government is complying with guidelines established in previous legal settlements.

Immigration lawyers have argued that the administration is detaining people longer than allowed by previous court settlements.

Immigrant advocacy groups have also said that arrests and detentions of pregnant women violate an ICE directive stating that the agency should not “detain, arrest, or continue to detain individuals known to be pregnant, postpartum, or nursing” except under exceptional circumstances.

ABC News previously reported on a different 21-year-old pregnant woman who has been detained at Dilly for more than 50 days with her 2-year-old son.

Immigrant advocates, medical professionals and lawmakers have previously raised concerns about conditions at the South Texas facility.

The order from the California judge also calls for the special master and independent monitor to monitor compliance with “adequate access to medical care” at Dilley.

DHS officials have previously disputed any allegations of substandard medical care at the detention facility.

A spokesperson for DHS said Gomez-Quiroz was convicted of illegal entry on July 6 and stated that she remains in ICE custody pending the outcome of her removal proceedings.

In response to concerns from Gomez-Quiroz’s family that she has been experiencing lower abdominal pain, a DHS spokesperson said, “It is a longstanding practice to provide comprehensive medical care from the moment a person enters ICE custody.”

“She’s been very depressed,” Ocampo told ABC News. “My mom is desperate … this is a very hard situation.

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Trump announces temporary pause on Canada tariffs, citing new deal

Trump announces temporary pause on Canada tariffs, citing new deal
Trump announces temporary pause on Canada tariffs, citing new deal
Canadian Prime Minister Mark Carney greets U.S. President Donald Trump at the official welcome ceremony during the G7 Leaders’ Summit on June 16, 2025 in Kananaskis, Alberta. (Photo by Chip Somodevilla/Getty Images)

(NEW YORK) — President Donald Trump said he is pausing for three days the new 50% tariffs on Canadian goods that were set to go into effect early Wednesday, citing a deal between the U.S. and Canada.

“I have paused the 50% Tariffs against Canada, that were scheduled to kick in tomorrow morning for a three day period, based on the fact that Canada and the U.S.A., subject to the finalization of documents, have a DEAL,” Trump said in a social media post on Tuesday night.

The new tariffs, targeting dozens of products from hockey sticks to wine, were set to go into effect at 12:01 a.m. ET on Wednesday.

Trump confirmed Wednesday that he had a “very good conversation” with Canadian Prime Minister Mark Carney on Tuesday night, repeating that he’d struck a deal to avert a 50% American tariff on a hodgepodge of Canadian goods for now.

“Yeah, we had a very good conversation with the Prime Minister last night, and we’ve come to a deal with Canada. As you know, the 50% tariffs across the board were going on against Canada today,” Trump said Wednesday.

The president claimed that as part of the Canadian deal, Canadian tariffs on American agricultural goods would be “non-existent.”

“The tariffs will be non-existent for our farmers. Our farmers were paying tremendous tariffs into Canada. And those tariffs are going to be totally eviscerated down to zero,” Trump noted.

Canada’s latest statement on the matter reflects that while “substantial progress” has been made, important work remains.

“As this work is ongoing, the United States has agreed to postpone the implementation of its 50% tariff on a range of Canadian goods under Section 338 of the U.S. Tariff Act of 1930 until end of day, August 21,” Carney said in a statement.

The U.S. Trade Representative’s official account on X responded to Trump’s announcement Tuesday, providing a bit of insight into what a final deal might entail. 
“The deal will include comprehensive market access for all American goods, economic security commitments, digital trade alignment, and many important provisions that will continue to protect our market and American workers, along with our Canadian partners,” the USTR posted.

Trump had suggested the deal might include a renewed effort to build the Keystone Pipeline, despite the project being canceled in 2021 after years of criticism about the project’s environmental impact.

“Keystone XL Pipeline, long ago killed by Sleepy Joe Biden, may be awoken from the grave!” Trump added in the post.  

Due to exemptions on key goods, the tariffs were expected to hit only a fraction of U.S. imports from Canada.

Still, the list of affected goods features an array of food items such as dairy products, honey, whey protein and molasses; as well as alcoholic beverages like whiskey and vodka.

It all comes weeks after Trump imposed sweeping new tariffs on 60 trade partners, including the European Union. Those levies ramped up an effort to reconstruct far-reaching duties struck down by the Supreme Court earlier this year.

Unlike previous tariffs, the new Canada tariffs would have applied to products compliant with the United States-Mexico-Canada Agreement, or USMCA, a free trade agreement. The levies included significant exemptions, however, leaving out some top Canadian imports such as oil, gas and potash.

Trump first announced the tariffs in a series of executive orders last month, saying the move had been made in retaliation for Canadian policies he considers discriminatory against U.S. exports.

“President Trump is offsetting the burden and disadvantage on U.S. commerce from Canada’s discriminatory treatment of U.S. commerce and is leveling the playing field for crucial American exports–cars, alcohol, and dairy,” the White House said at the time.

In a statement last month, Carney criticized a flurry of U.S. tariffs put forward since last year, saying Canada has “merely matched those measures.”

“This trade dispute has raised costs for families, particularly in the U.S. Canada stands ready to engage intensively to address outstanding issues with the U.S. to the mutual benefit of our citizens,” Carney said.

Trump has carried out on-again, off-again trade negotiations with Canada since he took office, aiming to resolve a dispute that began with tariffs announced by Trump early in his second term.

Trump sought to impose the tariffs under a legal authority enshrined in section 338 of the Tariff Act of 1930, which allows the president to enact levies up to 50% for countries found to have discriminated against the U.S. relative to their treatment of other nations.

The provision has never been invoked before, meaning the move lacks judicial precedent, Abigail Watt, an economist at UBS, said in a memo shared with ABC News.

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Trump picks White House aide Dr. Heidi Overton for top FDA job

Trump picks White House aide Dr. Heidi Overton for top FDA job
Trump picks White House aide Dr. Heidi Overton for top FDA job
Health and Human Services Secretary Robert F. Kennedy Jr. and Deputy Assistant to the President for Domestic Policy Dr. Heidi Overton attend an executive order in the Oval Office at the White House, August 10, 2026 in Washington. (Anna Moneymaker/Getty Images)

(WASHINGTON) — President Donald Trump said on Wednesday that he has nominated White House Domestic Policy Council Deputy Director Heidi Overton to be the next commissioner of the Food and Drug Administration.

“Dr. Heidi has been a ROCKSTAR in my Administration, where she has worked directly with Secretary Kennedy, Dr. Oz, and team, to deliver on the MOST TRANSFORMATIVE Health Agenda in History,” Trump said in a social media post, adding that he wants her “leadership at the FDA now to ensure that the U.S. remains the WORLD LEADER for Scientific Discovery and CURES.”

Overton has been Trump’s deputy assistant during his second term, advising him on health policies, including lowering prescription drug prices. Overton has stood alongside Trump for several major health announcements at the White House, including his executive order signing on childhood vaccines earlier this month.

She has espoused anti-abortion views and supported reductions to the childhood immunization schedule, touting the use of “gold-standard science” and restoring vaccination authority to parents while at that executive order signing.

Overton is a physician who holds a doctorate from Johns Hopkins University. Prior to that role, she was vice chair of the America First Policy Institute’s (AFPI) Center for a Healthy America, where Overton was also the chief policy officer, a nonprofit that aims to advance policies that it says put the American people first. AFPI was run by Agriculture Secretary Brooke Rollins before Rollins was tapped to join the president’s Cabinet. Several Trump administration officials held positions there before he was reelected, including Education Secretary Linda McMahon.

The FDA is one of several agencies under the Department of Health and Human Services, led by Secretary Robert F. Kennedy Jr.

The FDA commissioner position requires Senate confirmation. During confirmation hearings, Overton is expected to face questions that will test her loyalty to the president, similar to previous confirmation hearings for Trump administration health leaders.

If confirmed, Overton is expected to continue to support the president’s health agenda.

“She’s gonna stay in line because she’s tested,” a source familiar told ABC News. “She’s a loyalist to the president. That’s kind of his thinking behind all of this — to keep loyalists in these top jobs.”

The job is one of the nation’s top health posts and has remained without permanent leadership amid the foodborne illness outbreaks of cyclospora and salmonella

A senior administration official told ABC News that acting commissioner Kyle Diamantas was offered the full-time job several times and declined. Diamantas, who has been leading the investigation into the health outbreaks, has been touted as the driving force behind the administration’s food policy and stressed that America’s food supply is safe despite consumers’ health concerns.

Overton will ultimately be replacing former FDA Commissioner Marty Makary, who resigned in May amid clashes with the White House over pressure from Trump to authorize fruit-flavored vapes. FDA employees, who previously spoke to ABC News on the condition of anonymity, said that they were concerned about the future of the agency’s leadership after Makary’s exit. They said the angst stems from a rollercoaster-like experience, including witnessing 20% of the FDA’s staff being reduced during the president’s second term.

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Personalized mRNA cancer vaccine shows promise in extending lifespan in melanoma trial

Personalized mRNA cancer vaccine shows promise in extending lifespan in melanoma trial
Personalized mRNA cancer vaccine shows promise in extending lifespan in melanoma trial
Stock photo of a doctor examining a patient’s skin. (Lordhenrivoton/STOCK PHOTO/Getty Images)

(NEW YORK) — Merck and Moderna announced Wednesday that a personalized mRNA-based cancer vaccine succeeded in a large, late-stage trial among high-risk patients with melanoma.

The individualized vaccine, when paired with the existing immunotherapy, Keytruda, is the first and only combination regimen that demonstrated success in potentially extending melanoma patients’ lifespans.

In Phase 3 trials, the regimen significantly reduced the risk of cancer returning or spreading. The trial was conducted among patients whose high-risk melanoma had been surgically removed.

The combination treatment regimen pairs the personalized vaccine with Merck’s Keytruda, which had previously been used to treat the cancer alone.

The treatment showed a 49% reduction of melanoma return after patients underwent surgery and a 59% reduction of metastasization of the cancer to distant organs.

Key questions surrounding regulatory review of the vaccine remain.

The Food and Drug Administration has not yet approved the vaccine. The agency will review the full data once it has been collected and submitted.

While the FDA has already approved other cancer vaccines, this new treatment represents a step forward in the field as it uses mRNA technology and personalized treatment for each patient.

Merck and Moderna plan to present data at an upcoming international medical meeting where they hope to engage regulators on filing submissions for approval of the regimen, the companies said in a joint press release.

Dr. Ahmad Tarhini, an oncologist at the H. Lee Moffitt Cancer Center & Research Institute, told ABC News that he expects the treatment to be approved based on very positive trial results and made available to patients likely by early 2027.

The vaccine uses genetic information from patients’ individual tumors to identify and attack the cancer.

“It’s what we call individualized neoantigen therapy, where we take the cancer itself, we do genetic sequencing and try to define a unique mutational fingerprint of the cancer itself,” Tarhini said.

Melanoma is the deadliest form of skin cancer, with about 112,000 new cases expected in 2026, according to the American Cancer Society.

The treatment is considered relatively safe, according to the companies. The most common side effects include fatigue, sore arm and chills.

Treatments utilizing mRNA technologies are being used in trials for other forms of cancer, including that of the bladder, kidney, lungs, stomach and pancreas, according to Tarhini.

“I think it will certainly improve the outcome of our patients,” Tarhini said. “We are, you know, excited about this development. My expectation is this will eventually change the standard care of our patients.”

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