(SAN ANTONIO) — At least 51 people are dead after dozens were found inside a tractor-trailer in San Antonio on Monday evening in a suspected case of human smuggling, authorities said.

Of the 51 bodies in the custody of the medical examiner’s office, 39 are men and 12 are women, Rebeca Clay-Flores, the Bexar County Precinct 1 commissioner, said at a press conference Tuesday. Some of those found are under the age of 18, likely teenagers, she added.

At least 34 of the victims have been identified as of Tuesday afternoon, officials said.

The U.S. Immigration and Customs Enforcement (ICE) confirmed in a statement to ABC News on Tuesday that the total number of victims was 51 and that those who have been identified so far were from Mexico, Guatemala and Honduras. The criminal investigation remains ongoing, as Homeland Security Investigations (HSI) and partners continue to work to identify all of the victims, according to ICE.

It’s the deadliest incident of human smuggling in U.S. history, an HSI spokesperson told ABC News on Tuesday.

Mexican Foreign Secretary Marcelo Ebrard, citing information provided by U.S. authorities, said the death toll was at least 50, including 22 Mexican citizens, seven Guatemalan citizens and two Honduran citizens. The other victims have yet to be identified and Mexico is working with the U.S. on an investigation, according to Ebrard.

“We are in mourning,” Ebrard said in a statement Tuesday via Twitter. “Huge tragedy.”

The incident unfolded in the south-central Texas city on Monday evening at around 5:50 p.m. local time, when a nearby worker heard a cry for help and found the tractor-trailer with the doors partially opened and the bodies of 46 people inside, according to San Antonio Police Chief Bill McManus and San Antonio Fire Department Chief Charles Hood.

An additional 16 people — 12 adults and four children — were transported to area hospitals in what officials called a “mass casualty event.”

Chris Magnus, the commissioner of U.S. Customs and Border Protection (CBP), told reporters he was “horrified” by the incident.

“Horrified at this tragic loss of life near San Antonio,” Magnus said Monday. “This speaks to the desperation of migrants who would put their lives in the hands of callous human smugglers who show no regard for human life.”

The trailer was refrigerated but did not have a visibly working air-conditioning unit and there were no signs of water inside, according to Hood.

Three people are in custody in connection with the incident, according to McManus, who added that the case is now a federal investigation. One of the suspects was a driver who was spotted fleeing the scene by an eyewitness who called 911, McManus told ABC News.

Hood told ABC News that the the smell of meat tenderizer, which was reportedly put on top of the bodies before the suspects fled, was overwhelming.

The victims taken to hospitals were hot to the touch and all suffering from heat stroke and heat exhaustion, Hood said. There were no child fatalities that authorities know of so far, he added.

“They suffered, horrendously, could have been for hours,” Hood said.

Hood said there were personal items near where the bodies were found, including prayer cards in Spanish and a new pair of Air Jordan’s.

U.S. President Joe Biden issued a statement Tuesday calling the deaths “horrifying and heartbreaking,” blaming the criminal smuggling industry for preying on migrants. Biden also highlighted the anti-smuggling campaign the U.S. has launched with its partners, saying they have made over 2,400 arrests.

“Exploiting vulnerable individuals for profit is shameful, as is political grandstanding around tragedy, and my Administration will continue to do everything possible to stop human smugglers and traffickers from taking advantage of people who are seeking to enter the United States between ports of entry,” Biden said.

ICE said initially that HSI agents found more than 40 deceased individuals upon arrival at the scene on Monday when responding to a call from the San Antonio Police Department regarding “an alleged human smuggling event.”

“HSI continues its enforcement efforts to ensure the safety and well-being of our communities,” ICE said in its statement. “We will continue to address the serious public safety threat posed by human smuggling organizations and their reckless disregard for the health and safety of those smuggled. To report suspicious activity, we encourage people to call the HSI Tip Line at 1-866-DHS-2ICE. All calls are kept confidential.”

The San Antonio Fire Department confirmed to ABC News that HSI and CBP are taking over the investigation from local authorities.

CBP is the umbrella agency of the U.S. Border Patrol, which responded to assist at the scene and is supporting ICE in the federal investigation, according to Magnus, the CBP commissioner.

“We will be working with our federal, state and local partners to assist in every way possible with this investigation,” Magnus told reporters Monday night.

White House press secretary Karine Jean-Pierre said the Biden administration will “continue to take action to disrupt human smuggling networks which have no regard for lives.”

“Our prayers are with those who tragically lost their lives, their loved ones, as well as those still fighting for their lives. We are also grateful for the swift work of federal, state and local first responders,” Jean-Pierre told reporters Tuesday.

When asked about the criticism from Republicans, including Texas Gov. Greg Abbott, who say Biden’s border policies have led to dangerous journeys for immigrants, Jean-Pierre said the White House is focused on the victims and their families.

“But the fact of the matter is, the border is closed, which is in part why you see people trying to make this dangerous journey using smuggling networks,” Jean-Pierre said.

Homeland Security Secretary Alejandro Mayorkas took to Twitter to say that he was “heartbroken by the tragic loss of life today and am praying for those still fighting for their lives.”

“Far too many lives have been lost as individuals — including families, women, and children — take this dangerous journey,” he tweeted Monday night. “Human smugglers are callous individuals who have no regard for the vulnerable people they exploit and endanger in order to make a profit. We will work alongside our partners to hold those responsible for this tragedy accountable and continue to take action to disrupt smuggling networks.”

Earlier this month, the Department of Homeland Security released more details on the Biden administration’s efforts to combat human smuggling and unauthorized migration in conjunction with the Summit of the Americas held in Los Angeles.

The series of operations launched across the Western Hemisphere is part of the largest human smuggling crackdown ever seen in the region, with more than 1,300 deployed personnel and nearly 2,000 smugglers arrested in just two months.

Agencies from across the administration, including the intelligence community and the U.S. Treasury Department, have engaged to disrupt smuggling operations in real-time and strip down the financial backing of the transnational criminal organizations that coordinate these crimes.

“The Biden administration is focused on putting these organizations out of business,” DHS said in a recent statement prior to Monday’s incident. “But human smuggling is, by definition, a transnational problem and we are committed to working with our regional partners in the Americas to commit our collective expertise and resources to put an end to human smuggling.”

ABC News’ Luke Barr, Marilyn Heck, Matt Gutman, Robert Zepeda, Anne Laurent and Josh Margolin contributed to this report.

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(NEW HAVEN, Conn.) — Civil rights attorney Ben Crump has joined the legal team of Richard “Randy” Cox, a 36-year-old Black man who was injured while being transported by New Haven police in the back of a van.

Crump held a news conference with Cox’s family members in Connecticut Tuesday, along with co-counsel Jack O’Donnell and Louis Rubano, as well as local government and civil rights leaders.

New Haven police arrested Cox on June 18 for allegedly unlawfully possessing a firearm, without incident, after a person attending a block party reported that Cox was carrying a gun. Video of the arrest shows the officers then placed Cox in the back of a police van without seatbelts.

During an abrupt stop, Cox was thrown head-first into the back wall of the van, his lawyers said, and the video shows. When the van arrived at the police station, the video shows, he was still lying on the floor of the vehicle. Cox can be heard in the video telling the officers that he couldn’t move.

The surveillance video of the incident indicates that the officer driving the van and other officers present flouted protocol, the police department and Cox’s lawyers said, failing to wait for medical assistance and dismissing Cox’s pleas for help, allegedly assuming he was drunk.

In the video, one of the officers can be heard saying, “He just drank too much” and then later asks Cox, “Did you have any drugs or alcohol?” and “How much did you have to drink?” The footage also shows the officers dragging Cox by his feet and throwing him into a wheelchair, which his lawyers said could have exacerbated his already life-threatening injuries.

The case has prompted a state investigation and resulted in the officers involved being placed on administrative duty.

Crump said Cox’s case reminded him of the death of Freddie Gray, a Black man who was killed in 2015 while also being transported in a police van. Gray’s death was ascribed to injuries to his spinal cord.

“This is the Freddie Gray case on video,” Crump said. “Thank God, we got the video, so they can’t deny what happens. They can’t deny that they had a man handcuffed and put him in the back of this paddy wagon inappropriately and drove.”

Cox’s oldest sister, LaQuavius LeGrant, 39, said although he is in stable condition, Cox is currently paralyzed from the neck down, requiring a ventilator, breathing tube and feeding tube to survive. He is currently unable to talk and is unlikely to walk again, she said.

“It’s absolutely heartbreaking to go to that hospital room, the ICU, to look in his eyes — his eyes are awake — and can’t do anything about it,” she said. “Knowing that he would never walk again possibly, it’s disheartening. What happened is unacceptable and it’s inexcusable.”

Through tears, Doreen Coleman, Cox’s mother, said she and her family are nevertheless praying for Cox’s full recovery.

“I don’t want to see my son in that damn room with that thing on his neck, on his face,” she said. “I want him to keep coming in and out of the house, saying, ‘You alright? You need to go eat,’ or ‘You need something?’ Now I don’t know how long it’s going to be before he gets to go outside.”

LaToya Boomer, another one of Cox’s sisters, said she could barely finish watching the surveillance video of her brother. She demanded that the officers be held accountable for their actions.

“I’m calling for the officers involved to be fired and arrested,” she said. “And I’m calling for any bystanders that was watching but didn’t participate, that didn’t say anything, for them to be suspended and retrained because I always say, if you see something, say something, intervene.”

“Nobody said anything,” she added.

Crump also raised allegations that the officer driving the van could have been speeding or texting while driving. He said Cox’s family and legal team are demanding transparency from the police department about whether this was, in fact, the case.

The New Haven Police Department did not respond to ABC News’ request for comment. ABC News also reached out to the New Haven Police Union.

“We want the cell phone records. We want the transcripts from the inner department communications. We want the policies and procedures,” Crump said. “We’re going to fully explore … every possible legal remedy to give full justice, not just partial justice, but full justice to the family of Randy Cox and Randy Cox himself.”

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(IDAHO FALLS, Idaho) — A 34-year-old man is recovering from injuries sustained at Yellowstone National Park after he was charged at and brutally gored by a bison when he and his family got too close to the animal.

The incident occurred near Giant Geyser at Old Faithful on Monday when the unidentified man from Colorado Springs, Colorado, was walking with his family on a boardwalk at Yellowstone National Park when a bull bison began charging at them, according to a press release issued by the park.

“Family members did not leave the area, and the bull bison continued to charge and gored the male,” the statement from Yellowstone continued. “The male sustained an injury to his arm and was transported by ambulance to the Eastern Idaho Regional Medical Center.”

It is unclear whether the family had gotten too close to the animal or if the attack was unprovoked but Yellowstone officials confirmed that the incident remains under investigation and did not disclose any further information on the man’s condition.

Yellowstone warned that park regulations mandate people stay at least 25 yards away from bison at all times because they are unpredictable animals and can run three times faster than humans can.

“This is the second reported incident in 2022 of a visitor getting too close to the animal and the bison responding to the perceived threat by goring the individual,” said Yellowstone National Park.

That incident occurred just last month on May 30 when a 25-year-old woman from Grove City, Ohio, approached a bison within 10 feet near Black Sand Basin, located just north of Old Faithful at Yellowstone, causing the animal to charge at her. The victim was subsequently gored by the bison and tossed 10 feet into the air before she was immediately taken to the hospital for treatment, according to a statement from Yellowstone National Park released at the time of the incident.

“Yellowstone’s scenic wonders are sure to take your breath away: don’t let them take your life,” warns Yellowstone National Park on its page online for park safety. Some of the rules highlighted by the park include never approach wildlife, stay on boardwalks and trails in thermal areas, and never feed wildlife.

“Bison have injured more people in Yellowstone than any other animal,” says the park. “Always stay at least 25 yards (23 m) away from bison.”

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(NEW YORK) — Singer and convicted sexual predator R. Kelly will appear before a judge today for sentencing in a Brooklyn federal court for racketeering that involved a dozen separate criminal acts, including sex with underage girls.

The former R&B crooner, whose real name is Robert Kelly, could spend the rest of his life in prison. Federal prosecutors say he deserves to be sentenced in “excess of 25 years” due to the severe nature of his offenses.

In September, during his sex-trafficking trial, a jury found Kelly, 55, guilty on nine counts, including leading a criminal enterprise that recruited women and children for sex, which prosecutors called “calculated” and “methodical.”

During his trial, nearly four dozen witnesses testified for the prosecution, alleging that he preyed upon children and women for his sexual gratification.

He was also convicted in a bribery scheme involving a public official to get a fake ID for the late singer Aaliyah, so the two could marry when she was 15 and he was 27. Kelly believed Aaliyah was pregnant at the time, prosecutors wrote in a sentencing memo.

Kelly produced Aaliyah’s debut album, titled “Age Ain’t Nothing but a Number.” She died in a plane crash in 2001 at 22 years old.

“Kelly relied upon his fame, money and popularity as an R&B recording star and used the large network of people his status afforded him — including his business managers, security guards and bouncers, runners, lawyers, accountants and assistants to both carry out and conceal his crimes,” prosecutors said. “He continued his crimes and avoided punishment for them for almost 30 years and must now be held to account.”

The singer declined to testify at the six-week trial but could speak during Wednesday’s sentencing hearing. His defense team is asking for less than 14 years in prison, citing Kelly’s traumatic childhood.

In 2016, he revealed in a GQ interview that a female family member sexually abused him.

The defense also cast his accusers as motivated by money.

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