Tylenol caplets are displayed on September 22, 2025 in San Anselmo, California. The Trump administration will reportedly link use of the painkiller acetaminophen during pregnancy to autism during a White House press conference today. (Photo Illustration by Justin Sullivan/Getty Images)
(NEW YORK) — Texas Attorney General Ken Paxton sued the makers of Tylenol, Johnson & Johnson and Kenvue, claiming that they deceptively marketed the over-the-counter medication to pregnant women despite alleged links to autism and other disorders.
“Big Pharma betrayed America by profiting off of pain and pushing pills regardless of the risks,” Paxton said in a statement on Tuesday. “These corporations lied for decades, knowingly endangering millions to line their pockets. … By holding Big Pharma accountable for poisoning our people, we will help Make America Healthy Again.”
This is the first lawsuit from a state government since President Donald Trump claimed last month that Tylenol use during pregnancy is linked to an increased risk of autism, despite limited evidence to suggest an association.
Johnson & Johnson sold the drug for decades and its consumer health division spinoff, Kenvue Inc., has been selling the drug since 2023.
In a statement, Kenvue pushed back on the attorney general’s claims, saying it is “deeply concerned by the perpetuation of misinformation on the safety of acetaminophen and the potential impact that could have on the health of American women and children.”
“Acetaminophen is the safest pain reliever option for pregnant women as needed throughout their entire pregnancy. Without it, women face dangerous choices: suffer through conditions like fever that are potentially harmful to both mom and baby or use riskier alternatives. High fevers and pain are widely recognized as potential risks to a pregnancy if left untreated,” the statement read. “We will defend ourselves against these baseless claims and respond per the legal process. We stand firmly with the global medical community that acknowledges the safety of acetaminophen and believe we will continue to be successful in litigation as these claims lack legal merit and scientific support.”
This is a developing story. Please check back for updates.
A woman runs along a palm tree-lined street in La Jolla as the sun sets on the horizon of the Pacific Ocean on October 23, 2025 in San Diego, California. Kevin Carter/Getty Images
(NEW YORK) — Women may need less exercise than men to gain similar protection against coronary heart disease, according to a new study published in Nature Cardiovascular Research.
The findings come from an observational study of more than 85,000 adults in the United Kingdom who were followed for about seven years. Researchers used data from a one-time “snapshot” — a weeklong period of wrist-worn fitness tracker measurements — to examine how physical activity relates to heart disease risk and death rates.
The study found that women who got around four hours of moderate exercise each week lowered their risk of coronary heart disease by about 30%. However, men needed nearly twice as much — about eight hours of similar activity — to achieve the same level of heart protection. Additionally, women who already had heart disease experienced a threefold decrease in the risk of death compared with men with similar medical histories, who needed nearly twice as much weekly exercise to achieve a similar reduction in the risk of dying from any cause.
Moderate-intensity exercise includes activities like brisk walking or gardening — enough to get the heart pumping but not to the point of exhaustion, according to Dr. Jennifer Miao, a board-certified cardiologist and fellow of the ABC News Medical Unit. More vigorous workouts such as running, swimming laps or hiking uphill push the body harder and lead to a greater rise in heart rate, she explained.
The American Heart Association recommends that adults get at least two-and-a-half hours per week of moderate-intensity physical activity, or one-and-a-half hours per week of vigorous activity, or a combination of both. But even when following those exercise recommendations, the study found that differences between the sexes emerged.
Across all groups, the study confirmed that being active at any level was associated with a lower risk of heart disease compared with leading a sedentary lifestyle, with active women experiencing a 5% greater reduction in risk than active men.
And the more exercise someone got, the lower their risk of heart disease and death, highlighting what experts refer to as a clear dose-response relationship between physical activity and heart health.
There are two possible reasons women may benefit more from physical activity than men, according to the study authors. One explanation could be hormones.
“Physiologically, circulating estrogen levels are much higher in females than in males, and estrogen can promote body fat loss during exercise,” Dr. Jiajin Chen, one of the study’s authors and a researcher at the Institute of Cardiovascular Diseases in China, told ABC News.
Another possible reason has to do with muscle type. Men tend to have more “fast-twitch” muscles, which are great for quick, powerful movements. Women, on the other hand, usually have more “slow-twitch” muscles, which may help their bodies work a bit more efficiently during workouts.
“These physiological differences may partly explain the increased sensitivity to physical activity and greater cardiovascular benefit observed in females,” Chen said.
It’s also important to recognize how men and women can experience and be treated for coronary artery disease differently, Miao noted.
Women often develop the condition later in life, face a higher risk of death following a heart attack, and are less likely than men to undergo diagnostic procedures such as coronary angiography or receive standard medical care for coronary artery disease, she said.
Public health guidelines will benefit from acknowledging these sex-based differences to more effectively prevent cardiovascular disease, which is the world’s leading cause of death, the study authors suggest.
Miao agreed. She advised talking with your doctor before starting a new exercise routine, since physical activity recommendations depend on your fitness level, medical conditions, recent events like a stroke or heart attack, and overall mobility.
“Exercise routines should be personalized; it’s not a one-size-fits-all plan,” Miao said.
Dr. Cyrus Mowdawalla, MD, is a resident physician in internal medicine from Montefiore Medical Center and a contributing correspondent of the ABC News Medical Unit.
House Speaker Mike Johnson (R-LA) speaks at a press conference with other House Republicans on the 15th day of the government shutdown in Washington, DC on October 15, 2025. Nathan Posner/Anadolu via Getty Images
(NEW YORK) — As the federal government shutdown enters its third week, some Americans are worried about the future of the Affordable Care Act (ACA) subsidies.
The subsidies, or premium tax credits, help lower or eliminate the out-of-pocket cost of monthly premiums for those who purchase insurance through the health insurance marketplace.
They were enhanced during the COVID-19 pandemic and are currently set to expire at the end of 2025.
Democrats have been demanding that Republicans pass extensions of the subsidies before the government is reopened, while the GOP says it won’t negotiate until a clean funding bill passes and the government reopens.
A recent analysis from KFF found that premium payments could more than double in 2026 if the ACA enhanced premium tax credits expire.
Some Americans who rely on the tax credits to help pay for some or all of their or their family’s premiums told ABC News they’re worried that if the subsidies expire, they may be forced to choose a less comprehensive insurance plan or they may not be able to cover the cost of their premiums.
We ‘can’t afford to not have insurance’
Doug Butchart, 67, from Eglin, Illinois, told ABC News that his wife, Shadene, has amyotrophic lateral sclerosis (ALS), and currently receives her insurance through the health insurance marketplace.
Shadene Butchart, 58, started off on a Blue Cross bronze plan — or the lowest tier — but, as her disease progressed, the couple decided to upgrade to a gold plan, the highest tier, which covers a higher percentage of her health care costs.
The premium under this plan is $1,273.82 per month. The Butcharts receive enhanced premium tax credits that cover $670 of the monthly premium, leaving them to pay $603.82 per month themselves.
Without the premium tax credits, Doug Butchart said they cannot afford to pay the entire premium out of pocket each month.
“I’ve heard [premiums could rise] anywhere from 25 to 50%,” he said. “And that’s not sustainable because we can’t afford that but can’t afford to not have insurance.”
Doug Butchart said his wife doesn’t quality for Medicare and they don’t meet the income threshold to qualify for Medicaid.
“We’re stuck like in the middle because, normally with an ALS diagnosis, you’re automatically eligible for [Social Security Disability Insurance] and Medicare, but she doesn’t have any work credits, so she doesn’t qualify for Social Security Disability,” he explained. “So right now, we’re doing everything off of my Social Security, and it’s very hard to try and pay all the bills and keep insurance and, if they mess around with the marketplace insurance, it’s going to make it impossible for us to afford insurance.”
Now that the Butcharts have met the deductible for the year, combined with the anticipation of possibly losing tax credits and going to a lower tier insurance plan, the couple is trying to use insurance to get as much equipment as Shadene Butchart needs to manage her ALS before the end of the year.
This includes an order for a new wheelchair that Shadene Butchart could drive with her eyes, and that could cost anywhere from $65,000 to $95,000, Doug Butchart said.
Doug Butchart said they may have to downgrade to a lower-tier plan next year, but he’s not sure if the medications his wife currently takes will be covered by a “lesser plan.”
Doug Butchart, who is a retired mechanic, said he feels lucky that he does not need to worry about house or car payments — both of which are paid off — but there are other bills to pay and he did not expect to have to struggle to meet insurance costs every month.
“You work your entire life to make yourself comfortable and I’m sure there are things that we could do without but there’s not that much crazy spending to possibly have to cover $1,500 a month for insurance,” he said. “That’s a lot of money. … You don’t realize how important insurance is until you need it.”
‘It’s very much a worry’
Nancy Murphy, a retired registered nurse and insurance industry employee, was able to receive insurance through the ACA for the first time this year with Florida Blue.
Every month, her premium is $1,019 and the enhanced premium tax credits cover the total cost, she told ABC News. If there is no deal made before the Nov. 1 open enrollment deadline or the tax credits expire at the end of the year, she’s concerned about being able to cover the cost.
“It’s very much a worry. I definitely could not afford that if the tax credits expire,” said Murphy, 60, who lives in Fort Lauderdale. “It’s a scary thought as a type 1 diabetic.”
Murphy said she uses an insulin pump to manage her diabetes, which is covered by her insurance without a co-pay. However, she said she sometimes uses other medications that have a $30 a month co-pay.
She added that losing the tax credits is a concern because she has other costs she wants to make sure she can manage including property taxes and her daughter’s tuition for college in Boston.
Without knowing exactly how much premiums are going to increase by, she said she’s very anxious about what her budget will look like.
“I’m like in limbo and it’s a really uncomfortable feeling,” Murphy said. “I like to budget and plan out my budget. With tuition, property taxes and repairs that need to be done around the house, I need to map these out.”
She continued, “These things to me are so upsetting. We are American citizens. We should be able to access our tax dollars for our heath care needs.”
NIH-NIAID/Image Point FR/BSIP/Universal Images Group via Getty Images
(NEW YORK) — Health officials in Los Angeles County said on Friday they are investigating a possible local spread of a more severe strain of mpox.
Two cases of the strain were identified among Los Angeles County residents with no recent travel history.
It comes after the first U.S. case of the more severe strain of mpox without known travel was identified in a patient from Long Beach, California, bringing the total number of cases in the state to three.
No clear link has been identified between the Los Angeles cases and the Long Beach case, according to Los Angeles County health officials.
“The confirmation of a third case with no travel history raises concerns about possible local spread in Los Angeles County,” Dr. Muntu Davis, Los Angeles County health officer, said in a press release. “We’re working closely with our partners to identify potential sources and understand how this potentially more serious type of the mpox virus may be spreading.”
There are two types of the virus that cause mpox: clade I and clade II, with clade roughly meaning they are descended from a common ancestor organism. Clade I has historically been associated with severe illness and death, and is endemic to parts of central and western Africa, according to the Centers for Disease Control and Prevention (CDC).
Clade II was responsible for a large outbreak that peaked in summer 2022, leading to more than 100,000 cases in 122 countries, including more than 30,000 cases in the U.S.
The less severe strain in the U.S. has continued circulating at low levels and has remained relatively stable.
Parts of Africa have been dealing with sustained person-to-person spread of the more severe strain of mpox. All six previously confirmed cases of the more severe strain in the U.S. have been among people who had recently traveled to areas associated with the outbreak in central and eastern Africa, according to the CDC.
In November 2024, California reported the first domestic case of the more severe strain in a traveler from Africa who experienced mild illness.
People with mpox, which was formerly known as monkeypox, often get a rash that can be located on hands, feet, chest, face, mouth or near the genitals, the CDC said.
Most people with mpox typically recover within two to four weeks without specific treatments.
Currently, the JYNNEOS vaccine, a two-dose vaccine approved by the Food and Drug Administration to prevent smallpox and mpox, is the only vaccine being used in the U.S.
The JYNNEOS vaccine is recommended for adults at high risk for mpox, which includes people who are gay, bisexual or other men who have sex with men and have recent or upcoming risk factors like multiple sexual partners, intimate contact with someone who may have mpox, or sex at commercial venues.
ABC News’ Mary Kekatos contributed to this report.
NIH-NIAID/Image Point FR/BSIP/Universal Images Group via Getty Images
(NEW YORK) — The first U.S. case of a more severe strain of mpox without any recent travel history has been identified in California.
Health officials said this week that the case was confirmed in a Long Beach resident. The patient required hospitalization and is now isolating and recovering at home.
No other identifying details were provided about the patient, including name, age or sex.
While this is the seventh case of the more severe strain confirmed in the U.S this year, it is the first without known travel, according to local officials.
Officials say the risk to the general public is low and the health department is conducting an investigation, including working to identify the patient’s potential sources of exposure.
“We are taking this very seriously and ensuring our community and health care partners remain vigilant so we can prevent any more cases,” Long Beach Mayor Rex Richardson said in a press release. “This underscores the importance of continued surveillance, early response and vaccination.”
There are two types of the virus that cause mpox: clade I and clade II, with clade roughly meaning they are descended from a common ancestor organism. Clade I has historically been associated with severe illness and death, and is endemic to parts of central and western Africa, according to the Centers for Disease Control and Prevention (CDC).
Clade II was responsible for a large outbreak that peaked in summer 2022, leading to more than 100,000 cases in 122 countries, including more than 30,000 cases in the U.S.
The less severe strain in the U.S. has continued circulating at low levels and has remained relatively stable.
Parts of Africa have been dealing with sustained person-to-person spread of the more severe strain of mpox. All six previously confirmed cases of the more severe strain in the U.S. have been among people who had recently traveled to areas associated with the outbreak in central and eastern Africa, according to the CDC.
In November 2024, California reported the first domestic case of the more severe strain in a traveler from Africa who experienced mild illness.
People with mpox, which was formerly known as monkeypox, often get a rash that can be located on hands, feet, chest, face, mouth or near the genitals, the CDC said.
Most people with mpox typically recover within two to four weeks without specific treatments.
Currently, the JYNNEOS vaccine, a two-dose vaccine approved by the Food and Drug Administration to prevent smallpox and mpox, is the only vaccine being used in the U.S.
The JYNNEOS vaccine is recommended for adults at high risk for mpox, which includes people who are gay, bisexual or other men who have sex with men and have recent or upcoming risk factors like multiple sexual partners, intimate contact with someone who may have mpox, or sex at commercial venues.
ABC News’ Mary Kekatos contributed to this report.
(NASSUA COUNTY, N.Y.) — The New York State Department of Health has confirmed a case of locally acquired chikungunya on Long Island, marking the first case of the virus reported to be locally acquired in New York and the first locally acquired case to be reported in the United States since 2019.
Laboratory testing at the department’s Wadsworth Center confirmed the case in Nassau County on Long Island, according to health officials.
“An investigation suggests that the individual likely contracted the virus following a bite from an infected mosquito,” officials said. “While the case is classified as locally acquired based on current information, the precise source of exposure is not known.”
Chikungunya is a mosquito-borne disease most common in tropical and subtropical regions and symptoms include fever and joint pain, headache, muscle pain, joint swelling, or rash, officials said.
The disease cannot be spread directly from one person to another, authorities said, and the risk to the public is low.
The illness is rarely fatal, and most patients recover within a week, though some may experience persistent joint pain, authorities continued.
“People at higher risk for severe disease include newborns infected around the time of birth, adults aged 65 and older, and individuals with chronic conditions such as high blood pressure, diabetes or heart disease,” according to the New York State Department of Health.
The Aedes albopictus mosquito, which is known to transmit chikungunya, is present in parts of downstate New York and local transmission can occur when an A. albopictus mosquito bites an infected traveler, becomes infected and bites another person.
“Our Wadsworth Center has confirmed this test result, which is the first known case of locally acquired Chikungunya in New York State. Given the much colder nighttime temperatures, the current risk in New York is very low.” State Health Commissioner Dr. James McDonald said. “We urge everyone to take simple precautions to protect themselves and their families from mosquito bites.”
In 2025, there have been three additional chikungunya cases outside New York City that were all linked to international travel to regions with active chikungunya infections, according to health officials.
“Routine mosquito testing conducted by the Department’s Wadsworth Center and the New York City Department of Health and Mental Hygiene (DOHMH) has not detected chikungunya virus in any New York mosquito samples to date,” said the New York State Department of Health.
Health officials said that all New Yorkers should take precautions to reduce the risk of mosquito bites by using EPA-registered insect repellents, wearing long sleeves, long pants and socks outdoors when possible, removing standing water around homes, such as in flowerpots, buckets and gutters, and by repairing or patching holes in window and door screens to keep mosquitoes out.
(WASHINGTON) — As the federal government shutdown enters its tenth day, one major health care issue has continued to be a sticking point: insurance subsidies.
The Affordable Care Act (ACA) subsidies, or premium tax credits, help lower or eliminate the out-of-pocket cost of monthly premiums for those who purchase insurance through the health insurance marketplace.
Eligibility for the subsidies can include factors such as household income and geographic location.
The subsidies were part of the original Affordable Care Act passed during the Obama administration and were enhanced during the COVID-19 pandemic to increase the amount of financial assistance to those who were already eligible and to expand eligibility to more people. They are set to expire at the end of the year.
Republicans have said the expansions from the pandemic era went too far and have tried to persuade Democrats to fund a temporary spending bill that doesn’t address the expiring ACA subsidies, with promises of discussing ways to continue the subsidies later.
House Speaker Mike Johnson, R-La., referred to the Dec. 31 deadline to extend subsidies as being far away.
“That’s a Dec. 31 issue,” he said during a news conference earlier this week. “There are lots of conversations and deliberations and discussions right now, even bipartisan amongst members about necessary changes that would have to be made, pretty dramatic changes to even have that considered on the floor. But look, I’m not going to forecast the outcome of that.”
However, Democrats say that with open enrollment for ACA plans beginning Nov. 1, the subsidies not being approved could be detrimental for millions of American families.
“The Democrats have said that their position on getting out of the shutdown period is that they would want to both extend and make permanent these enhanced marketplace premium tax credits,” Melinda Buntin, a professor at Johns Hopkins Bloomberg School of Public Health and Johns Hopkins Carey Business School, told ABC News.
“The thing at the very top of the list is these subsidies because they are so salient and they will directly affect the pocketbooks of so many millions of Americans,” Buntin said.
Buntin said that if open enrollment begins and these subsidies are not approved and loaded into the enrollment systems, people are likely to see their premiums go up.
Estimates from the Congressional Budget Office suggest that, without an extension, gross benchmark premiums could increase by 4.3% in 2026 and by 7.7% in 2027 for those on marketplace plans.
A KFF analysis last month found that people who buy insurance from the marketplace, and receive financial assistance, would see their premiums rise by about 114% on average, from $888 in 2025 to $1,904 in 2026.
There is broad support for the tax credits. A recent KFF poll, which was fielded just before the government shut down on Oct. 1, found that 78% of Americans support extending the enhanced tax credits, including more than half of Republicans and of “Make America Great Again” supporters.
House Minority Leader Hakeem Jeffries expressed on Thursday the need to extend tax credits, stating, “[U]nless we extend the Affordable Care Act tax credits, tens of millions of Americans are about to experience dramatically increased premiums, co-pays and deductibles by thousands of dollars per year.”
Buntin says this could affect many Americans, but particularly those who live in states where Medicaid was not expanded and buying insurance on the marketplace is their only option.
Naomi Zewde, a fellow at the UCLA Center for Health Policy Research and assistant professor of health policy and management at the UCLA Fielding School of Public Health, told ABC News that working low-income families and adults will be affected if the ACA subsidies are not approved.
“Mainly those who don’t get insurance through their job, who make too much for Medicaid but not enough to pay [about] $600-plus per month for a plan with a two-to-three-thousand-dollar deductible,” she said.
However, James Blumstein, university distinguished professor of constitutional law and health law and policy at Vanderbilt University School of Law, told ABC News that even if the subsidies lapse and the Nov. 1 deadline arrives, a deal could be worked out to retroactively fix the issue.
He added that he believes congressional Democrats and Republicans could also come up with a deal that saves the ACA subsidies but doesn’t keep the full expansions that were offered during the pandemic.
“I think the leverage for the Democrats will diminish,” he said. “Republicans have passed a continuing resolution so that this issue is going to come back up five or six weeks again.”
Blumstein continued, “Democrats will have leverage again in five or six weeks and I think that whether this goes into the period of new enrollment or not, that can all be fixed in the deal. In other words, if the time lapses that can be overcome by the subsidies coming a little bit later.”
Earlier this week, President Donald Trump indicated that he was negotiating with Democrats on health care policy and that he was open to making a deal on health care subsidies in an attempt to reopen the government.
“We have a negotiation going on with the Democrats that could lead to good things, and I’m talking about good things with regard to health care,” Trump told reporters in the Oval Office.
“If we made the right deal, I’d make a deal. Sure,” Trump said in reference to making a deal to approve ACA subsidies.
In a statement, Senate Minority Leader Chuck Schumer denied that the White House was negotiating with Democrats.
Trump later walked back his willingness to make a deal, writing on social media that he would work with Democrats as long as the government is reopened first.
Democratic leaders have said they are not willing to vote to reopen the government unless Republicans negotiate on health care demands, while Republicans have signaled unwillingness to negotiate on health care policy unless the government is reopened — an effective stalemate.
“Republicans are saying that we should have what is referred to as a clean bill, just continue the government operations as they were, without extending these subsidies, and then once we’ve got that, then we can come back and we can talk about things like extending the subsidies,” Buntin said. “Democrats are seen so far unwilling to agree to that, which I think represents a sort of breakdown in normal process.”
She continued, “Democrats are seeing a political opening, because there are so many millions of people who depend on these subsidies to be able to afford health insurance, and there’s nothing like a deadline to use to get something you want.”
A spokesperson for the Department of Health and Human Services told ABC News in a statement earlier this week that Democrats are to blame for the shutdown.
“Senate Democrats are choosing to keep the government shut down, putting major health programs at risk. They should do the right thing and vote to reopen the government,” the statement read.
Health and Human Services Secretary Robert Kennedy Jr. appears before the Senate Finance Committee at the Dirksen Senate Office Building on September 04, 2025 in Washington, DC. The committee met to hear testimony on President Trump’s 2026 health care agenda. (Photo by Andrew Harnik/Getty Images)
(WASHINGTON) — The Department of Health and Human Services (HHS) hit back at an op-ed written by the most recent six surgeons general, who said they wanted to warn the U.S. about the dangers of Secretary Robert F. Kennedy Jr.
The op-ed, published in The Washington Post on Tuesday, called the health secretary’s policies and positions an “immediate and unprecedented” threat to the nation’s health.
In a statement to ABC News, HHS spokesperson Andrew Nixon said the doctors are the same officials “who presided over the decline in America’s public health.”
They “are now criticizing the first Secretary to confront it head-on,” the statement continued. “We remain committed to restoring trust, reforming broken health systems, and ensuring that every American has access to real choice in their health care.”
In the op-ed, the surgeons general referenced views held by Kennedy, including repeating the false claim that childhood vaccines cause autism and misrepresenting risks of COVID-19 vaccines, despite studies that found the shots prevented millions of hospitalizations and deaths.
The “nation’s doctors” as surgeon generals are commonly described because they give public health guidance and warnings to the country, also pointed to decisions made by Kennedy — including touting unproven treatments as measles spread in the U.S.
Among the authors was Dr. Jerome Adams, who served as surgeon general for most of President Donald Trump’s first term, including the early days of the COVID-19 pandemic.
In a post on X sharing a link to the op-ed, Adams referred to disinformation, the loss of trust in doctors and the destruction of public health as deadlier than cigarettes.
“Neither I nor the other five living Surgeons General wanted to call for this unprecedented warning- but all felt compelled by duty to do so,” he wrote.
Dr. Richard Carmona, who served as surgeon general under President George W. Bush from 2002 to 2006 and another author of the op-ed, told ABC News he is urging Americans to “disregard” Kennedy’s vaccine rhetoric.
“On behalf of the people, vaccines are safe, you should consult with your health provider, get the best information, get your child vaccinated, and unfortunately, disregard what you’re hearing from Secretary Kennedy and many of his political appointees who continue to provide mis and disinformation to confuse the public,” he said.
The op-ed comes about a month after seven former directors and two former acting directors of the CDC wrote an op-ed for The New York Times, accusing Kennedy of endangering the health of Americans.
ABC News’ Meghan Mistry and Cheyenne Haslett contributed to this report.
Stock image of stethoscope. ATU Images/Getty Images
(NEW YORK) — A fast-rising form of breast cancer that’s harder to detect on mammograms now makes up more than one in ten cases in the United States, according to a new report from the American Cancer Society (ACS).
Invasive lobular carcinoma, the second most common breast cancer type, is increasing about 3% each year, more than triple the rate of other breast cancers, the report, published on Tuesday morning, found.
About 80% of breast cancers are the invasive ductal type, which occurs when cancer cells grow in the milk ducts and invade the surrounding breast tissue.
However, incidence of invasive lobular carcinoma, a cancer than develops in the milk-producing glands of the breast — once rare — has doubled since the 1970s.
Lobular breast cancer hasn’t drawn much attention partly because many people view the five-year survival rate, which is over 90%, as a “cure rate,” but survival often drops after that point, Rebecca Siegel, an author of the report and senior scientific director of surveillance research at the ACS, told ABC News.
“And so, if you look at five-year survival, actually women with lobular breast cancer do better than ductal breast cancer,” she said. “I think that’s probably why it hasn’t gotten a lot of attention.”
However, Siegel added that the long-term outlook is poorer than for other breast cancer subtypes.
“For metastatic disease, women with lobular breast cancer are about half as likely to be alive at 10 years,” she said.
Lobular cancers are rising even faster for women under 50, at more than twice the rate of other breast cancers, the report found.
The cancer is most common in white women, with about 14 cases per 100,000 — 33% to 55% higher than in other racial and ethnic groups — but the fastest rise, at nearly 4.5% a year, has been seen among Asian American and Pacific Islander women.
Diagnosing and treating lobular breast cancer differs from other types in several ways, Dr. Anita Mamtani, a surgical oncologist specializing in breast cancer at Memorial Sloan Kettering Cancer Center, told ABC News.
Mamtani explained that instead of forming a lump, “lobular cancers tend to grow in a straight line or sheet-like patterns.”
This growth pattern can make lobular tumors harder to spot on mammograms, Mamtani said. Patients tend to notice subtle changes such as breast fullness, firmness, swelling, skin redness, nipple changes or discharge.
Compared with other types of breast cancer, lobular cancers are also less responsive to some treatments and more likely to occur in both breasts, which may contribute to poorer long-term outcomes, according to the report.
However, lobular breast cancer still has a strong outlook when found early. The five-year survival rate for early-stage disease is about 99%, and overall survival across all stages is roughly 91%. Outcomes are even better for women who keep up with regular breast cancer screening.
“We will use a variety of diagnostic tools for most patients but, for lobular cancer, that arsenal will include not only mammograms but also ultrasound, contrast-enhanced mammograms, and MRIs,” Mamtani said.
With proper screening, lobular cancer can often be caught in its early stages, she added.
Overall, breast cancer deaths have dropped 44% since 1989, but the disease still affects one in eight women and remains a leading cause of cancer death, according to the ACS.
For all types of breast cancer, regular mammograms remain the best way to catch disease early. For women at average risk, the U.S. Preventive Services Task Force recommends screening every two years from ages 40 to 74.
Women who are at higher risk with a family history of breast cancer or other risk factors should discuss timing of screening with their health care provider.
Nearly half of uninsured women skip breast cancer screening because of cost concerns, the report noted. Free or low-cost options are available through the Centers for Disease Control and Prevention, the National Breast Cancer Foundation, the American Breast Cancer Foundation and local programs.
Experts also recommend maintaining a healthy weight, staying active, limiting alcohol and speaking with your doctor about personal risk factors.
Jamie Parkerson, MD, MS, is a fourth-year psychiatry resident and a member of the ABC News Medical Unit.
Detail of vials and syringe containing a COVID-19 vaccination by Pfizer at Kaiser Permanente Venice Medical Office Building in Culver City Tuesday, Sept. 23, 2025. (Allen J. Schaben / Los Angeles Times via Getty Images)
(NEW YORK) — The Centers for Disease Control and Prevention (CDC) updated its immunization schedule on Monday, dropping the universal COVID-19 vaccine recommendation and recommending that toddlers receive the chickenpox shot separately from the measles, mumps and rubella (MMR) shot.
Acting Director and Deputy Secretary of Health and Human Services Jim O’Neill signed off on the recommendations, which were made by the CDC’s Advisory Committee on Immunization Practices (ACIP) last month.
“Informed consent is back,” O’Neill said in a statement. “CDC’s 2022 blanket recommendation for perpetual COVID-19 boosters deterred health care providers from talking about the risks and benefits of vaccination for the individual patient or parent. That changes today.”
Last month, the ACIP voted to abandon its previous universal recommendation for annual COVID-19 vaccine shots for anyone aged 6 months and older, instead suggesting that Americans can get the vaccine “based on individual-based decision-making,” or a personal choice.
The panel also voted to no longer recommended children around 12 months old receive the first dose of the combined measles, mumps, rubella and varicella (MMRV) vaccine.
Instead, the committee recommended that children receive two separate shots, one for the combined MMR shot and a second shot for chickenpox. The MMRV shot will be recommended as an option for a child’s second dose, typically given at around 4 to 6 years old.
This is a developing story. Please check back for updates.
