As COVID-19 surges again, what experts say about the millions of unvaccinated

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(NEW YORK) — As Americans start packing bars and live venues once again in the age of mass COVID-19 vaccination — with many abandoning masks and social distancing measures — a concerning reality check is taking place.

Health officials and front-line workers, particularly in pockets of the country with relatively low vaccination rates, are again warning the public that they are seeing an influx of unvaccinated patients who are becoming severely ill.

“This is the absolute worst that I’ve ever seen it,” Emily McMichael, a nurse at Mercy Hospital in Springfield, Missouri, told ABC News.

Nationally, more than 17,000 patients are currently receiving care around the country, the highest number in over a month, according to data from the Centers for Disease Control and Prevention.

The average number of new COVID-19 hospital admissions has also increased dramatically — to nearly 2,800 admissions a day — up by 35.8% in the last week.

And the distribution is fairly widespread: over a dozen states have seen significant increases in the number of patients coming into their hospitals in need of care, including Arkansas, which has seen a 76.4% increase in hospital admissions over the last two weeks, and Florida, with a nearly 90% increase.

Experts say the outlook for the country is mixed — while there won’t likely be a nationwide wave like spring 2020 or last winter, there is the possibility of regional surges in unvaccinated areas. And that spread can pose some dangers to the vaccinated population, specifically those who are vulnerable and in the possible creation of new variants that can mitigate or evade vaccines.

‘Nasty’ delta variant

Although there are still significantly fewer patients receiving care than the peak in January, when 125,000 patients were hospitalized, experts warn the uptick is concerning, particularly as the delta variant continues to spread rapidly across the U.S.

The highly infectious COVID-19 strain, which the nation’s top infectious disease expert, Dr. Anthony Fauci called “nasty,” is now estimated to account for more than 57% of new cases nationwide. At the end of May, the variant was estimated to account for just over 3% of new cases.

Although it is still unknown whether the delta variant is more deadly than other variants, experts say it is more dangerous, given how quickly it spreads between people, thus, causing a greater number of infections, and therefore more illnesses and deaths overall.

This rapid spread has caused cases to increase in nearly every state in the country, according to data from Johns Hopkins University, with the national case average doubling in the last three weeks.

However, given the variation in vaccination levels from state to state and even community to community, its effects have varied widely.

“The impact of the more transmissible delta variant will not be felt in a uniform way across the country. Major pockets of unvaccinated people will continue to be the main hosts that will allow this virus to circulate,” said John Brownstein, Ph.D., the chief innovation officer at Boston Children’s Hospital and an ABC News contributor.

“While vaccines will likely prevent a major national wave, tens of millions of Americans with no prior immunity still remain susceptible to the delta variant,” he added.

Communities with fewer vaccinations see significantly higher case rates

A new ABC analysis has found that over the past week, states that have fully vaccinated less than 50% of their total population have reported a weekly average coronavirus case rate that is three times higher than in states that have fully vaccinated more than half of their residents.

States that have fully vaccinated more than half of their residents reported an average of 15.1 new COVID-19 cases per 100,000 people over the last week, compared to an average of 45.1 cases per 100,000 people in states that have vaccinated less than half of their residents.

The 14 states with the highest case rates all have fully vaccinated less than half their total population, and 10 out of the 11 states with the lowest case rates have fully vaccinated more than half of their total population, with the exception being South Dakota.

“In unvaccinated communities where you have increased mobility and reduced mask use and social distancing, we will continue to witness surges and unfortunately unnecessary hospitalizations and deaths,” Brownstein said.

With nearly 90% of Americans 65 years and older vaccinated with at least one dose, young Americans appear to be driving this recent increase. According to CDC data, 18- to 24-year-olds currently have the nation’s highest new case rate, with only 41.6% of the age group fully vaccinated.

The widespread national impact

For now, experts say they do not foresee a nationwide surge.

“It’s likely that COVID-19 is now moving into a phase where it’s a regional problem and not a systemic problem for the country, because of the differential in vaccinations. Fully vaccinated areas are going to see a very blunted impact of delta,” said Dr. Amesh Adalja, senior scholar at Johns Hopkins Center for Health Security.

Dr. Angela Rasmussen, a virologist at the Georgetown Center for Global Health Science and Security, concurred, telling ABC News that “a surge in Missouri probably doesn’t mean much for states with high vaccination rates in terms of hospitalizations.”

However, large regional surges in areas of low vaccination could spark major problems for states with fewer health care resources, making the focus on hospital capacity urgent, the experts said.

But surges in under-vaccinated areas can pose a broader nationwide risk for those who are fully vaccinated but remain vulnerable.

“Uncontrolled transmission and population mobility means additional breakthrough infections in vulnerable populations, regardless of whether they happen to be in a state that has good vaccination coverage,” Brownstein said.

This is why some local health departments are again considering reinstating restrictions, in the hope of containing infections. On Tuesday, the Chicago Department of Public Health announced that unvaccinated travelers from Arkansas and Missouri, which have both recently experienced significant COVID-19 resurgences, will have to either quarantine for 10 days or present a negative COVID-19 test result.

In Los Angeles County, the nation’s largest, officials on Thursday reinstated a mandatory indoor mask mandate — regardless of vaccination status.

Brownstein also stressed the critical importance of containing the virus, because “unmitigated transmission further increases the probability that a variant with vaccine-evading properties might emerge.”

Although Rasmussen believes that it is unlikely that we will see the emergence of a variant that will fully evade vaccines, it is possible a new variant could reduce effectiveness enough to be problematic. In such a case, she said, boosters would become necessary.

Ultimately, said Adalja, “I think it has to be made very clear to people that the delta variant is a disease of the unvaccinated. The breakthrough infections that are occurring in vaccinated people are very, very rare, and not usually clinically significant.”

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Why young adults remain hesitant about the COVID-19 vaccine

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(NEW YORK) — Starting next week, 150 Connecticut college students will begin training to go out into communities in their state that are lagging in vaccination rates and try to combat COVID-19 vaccine hesitancy among young adults.

The program comes as the nation enters a period where the delta variant is surging in some locations and officials are having difficulty convincing millions of Americans to get vaccinated — currently the best hope of averting yet another wave of COVID-19.

Officials nationwide are trying to reach unvaccinated people — in particular those between the ages of 18 and 24, who have lower rates of getting the shot when compared to older age groups and the highest rates of COVID-19 cases.

“It really is meeting people where they are, giving them the important information for them to be able to make the decision for themselves,” Janelle Chiasera, dean of the School of Health Sciences at Quinnipiac University, which is working with the state health department on the Connecticut Public Health College Corps program, told ABC News. “What we’re trying to do is to get those people who are on the fence, over that fence to get the vaccine.”

Unvaccinated adults are “significantly younger,” according to the Kaiser Family Foundation’s latest vaccine monitor report; 29% of the unvaccinated are 18- to 29-year-olds, compared to 17% of those vaccinated, for the smallest percentage of adults vaccinated.

According to the Centers for Disease Control and Prevention, 41.8% of Americans ages 18 to 24 are fully vaccinated, compared to 66% of those ages 50 to 64 and 80.9% of those ages 65 to 74.

The reasons are myriad, including fear of side effects, but experts stress the need to overcome that hurdle through targeted and trusted messaging.

“The more unvaccinated people you have, the more the chances that we’re setting up this virus to be able to create another variant,” Chiasera said. “We are allowing that virus to get smarter.”

Concerns about side effects

The reasons behind the reluctance are varied and not fully known. One may be the “lingering effects” of not prioritizing younger populations during the initial vaccine rollout, Dr. Monica Schoch-Spana, a senior scholar at the Johns Hopkins Center for Health Security and co-leader of CommuniVax, a national rapid research coalition focused on improving vaccine equity in Black, Hispanic/Latino and Indigenous communities, told ABC News.

A new study by University of California San Francisco researchers published in the Journal of Adolescent Health this week found that about 1 in 4 unvaccinated people between the ages of 18 and 25 said that they “probably will not” or “definitely will not” get the COVID-19 vaccine.

“There’s still that lingering perception that ‘I am young, I am strong, I can fight this thing off,'” Schoch-Spana said. “So there’s that youthful sense of invincibility that was reinforced early on when we had less vaccine available.”

Older adults and those with underlying conditions diagnosed with COVID-19 generally fared dramatically worse than those who were younger — more than 95% of deaths were in those 50 and older, according to CDC data.

Others are worried about potential side effects of the vaccine. A CDC report published last month found that one of the main reasons U.S. adults between the ages of 18 and 39 were not vaccinated were due to concerns about possible side effects. The UC San Francisco study found that was a concern for more than half of respondents. Neither study specified what those concerns were.

In a survey of patients at its California sites last month, COVID-19 testing and vaccination startup Curative also found that the number one reason people hadn’t gotten vaccinated until that point was due to concerns about side effects, according to Alexandra Simon, director of vaccines for the state.

“It could mean that they’re worried that they’re gonna have to miss work, they’re worried about cab fare, or they’re just kind of worried about getting sick,” Simon told ABC News. “I think there’s a ton of misinformation floating around about side effects.”

Chiasera said she has also heard concerns about blood clots and “fertility issues in women.”

The single-dose Johnson & Johnson vaccine has been associated with an extremely rare but severe blood clot disorder and, more recently, a rare neurological disorder called Guillain-Barre.

Experts and public health officials maintain that any risks from the vaccine are outweighed by the benefits. The vast majority of side effects are mild, and long-term side effects are “unlikely,” according to the CDC. Additionally, researchers have found that there’s a greater risk of developing clots from COVID-19 than from the vaccines.

Meanwhile, there is no evidence that any vaccines, including the COVID-19 vaccines, affect fertility in women or men, according to the CDC.

‘No sole, single identity’

More education could help with vaccination efforts. The CDC report on vaccination in young adults found that about two-thirds of respondents who were not sure about getting vaccinated reported they didn’t have adequate information about vaccine safety or effectiveness.

“There’s a lot that we see on social media about vaccines, but not a lot that people really truly understand about them,” Chiasera said.

Through Connecticut Public Health College Corps, the trained students will attend vaccine clinics, community efforts and do other outreach over the course of four weeks and be there to answer people’s questions on topics like the availability, safety and efficacy of the vaccines and side effects, Chiasera said.

“We’re realists in knowing that there are people — it doesn’t matter what you say, it doesn’t matter what you do — they’re not going to get their vaccine, but that is a small percent,” she said. “There’s a lot more people that are on the fence, and I think our best efforts are really on those people that are on the fence — that really truly have questions that they need answered to help make that decision.”

As much attention is being paid to reaching unvaccinated young adults, vaccination is a hyperlocal effort that can’t be generalized, Schoch-Spana said.

“One can’t expect some magic bullet to get everybody between the ages of 18 and 28 showing up in large numbers,” she said. “You really do have to think about, OK, if I want to target college-aged kids, what should I be doing? If I wanted to target Spanish-speaking youth, where do I need to go?”

“There’s no sole, single identity, so a youth-oriented vaccination campaign has to think about the different kinds of youths that are out there and to develop very specific communication approaches, outreach approaches and delivery locations to meet youth where they are,” she added.

‘Trusted influencers’ needed

It largely boils down to trust, and who the “trusted influencers” are, Schoch-Spana said.

Through its research, she said, CommuniVax has seen that in Black communities in rural Alabama, grandparents are the ones advocating for their grandchildren to get vaccinated; meanwhile, in Hispanic/Latino communities in rural Idaho, the younger generation is helping grandparents get shots.

“Different age groups have different levels of influence, according to where they are in their family and also the larger community,” she said.

In its survey of its California vaccination sites, Curative found that one reason why someone who was previously hesitant to get vaccinated ultimately did was because “someone I trust convinced me.”

A majority of patients at its California vaccination sites came based on referrals, most of which were from people who had been vaccinated at the site, Curative learned. After realizing that, they started a program dubbed “Vax Tripling,” based on the political organizing concept of vote tripling.

“It’s the idea that every person who commits to vote, you also ask them which three people they can talk to about voting,” Simon said. “So it’s kind of leveraging that trusted messenger network that happens organically.”

To further spur referrals, Curative created business cards with information about the site for patients to give to those in their community to turn “every person who chooses to get vaccinated into an ambassador for vaccination in general, in a way that is authentic to the community and real to their relationships,” Simon said.

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COVID-19 complications could strain health system for years

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(NEW YORK) — Half of patients hospitalized with COVID-19 developed complications associated with the virus, prompting experts to warn that long-term problems from COVID could strain the health system for years, according to new research out of the United Kingdom.

The study, published Thursday in the Lancet, analyzed hospital records from 73,197 adults in the U.K. who were hospitalized with severe COVID-19. Of those patients, 36,367 developed one or more complications during their hospitalization, including kidney problems, complex respiratory disease (such as bacterial pneumonia), acute respiratory distress syndrome, neurological problems (like seizures or stroke) and heart problems.

Overall, men and patients older than 60 were most likely to have complications, and the incidence of complications rose with age. Still, even young and previously healthy people had relatively high levels of complications. Among 19- to 29-year-olds, 27% developed complications, compared with 37% of 30- to 39-year-olds and 43% of 40- to 49-year-olds.

“This work contradicts current narratives that COVID-19 is only dangerous in people with existing comorbidities and the elderly,” Calum Semple, a professor at the University of Liverpool and coauthor of the paper, said in a statement. “Disease severity at admission is a predictor of complications even in younger adults, so prevention of complications requires a primary prevention strategy, meaning vaccination.”

The study also pointed to racial disparities in patient outcomes. White, South Asian and East Asian patients had similar rates of complications, but Black patients (58%) were more likely to develop complications than white patients (49%).

Following hospitalization, roughly a third of patients were less able to look after themselves than prior to contracting the virus, an effect that was most pronounced among men, older patients and those who’d been in critical care. Neurological complications had the biggest impact on patients’ ability to care for themselves.

“Policy makers and health-care planners should anticipate that large amounts of health and social care resources will be required to support those who survive COVID-19,” the study authors noted. “Data on long-term health difficulties posed by COVID-19 will be of great importance, particularly as a large proportion of COVID-19 survivors come from economically active age groups.”

The study had a few limitations. Since the research was conducted in the U.K., which has a different population and medical system than the United States does, the results can’t necessarily be extrapolated to the U.S. population. The study period (Jan. 17 to Aug. 4, 2020) took place toward the beginning of the pandemic and before vaccines were widely available, meaning the population skewed older. More research needs to be done to determine whether COVID-related health complications are temporary or enduring.

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Mom shares warning about extreme thirst, wet diaper after son diagnosed with Type 1 diabetes

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(NEW YORK) — A California mom is sharing a warning for other parents after her 16-month-old son’s wet diapers ended in a diagnosis of Type 1 diabetes, a chronic disease.

Courtney Moore, of Sacramento, said she began to notice in early July that her son, Maddox, was waking up with soaking wet diapers each morning.

She also noticed the toddler was waking up each morning extremely thirsty.

“When he woke up he would be so ferociously thirsty and reaching for my water bottle and chugging it,” Moore told ABC News’ Good Morning America. “I knew that wasn’t normal.”

Moore said she reached out to fellow moms on Facebook for ideas and searched the internet on her own, but did not believe Maddox’s symptoms were signs of Type 1 diabetes, an autoimmune disease in which the pancreas makes little to no insulin, according to the Centers for Disease Control and Prevention.

“When you do a Google search, what pops up is Type 1 diabetes, but we don’t have a family history of that,” she said. “Since we had no knowledge of Type 1 diabetes, I could justify all the different signs we were seeing.”

Moore said that, for example, she and her husband, Jason, attributed Maddox’s thirst to the hot weather of summer and the slight weight loss they noticed to the fact that he was an active toddler who was now walking.

After noticing that Maddox seemed more and more “off,” according to Moore, they took him to the doctor for bloodwork.

One hour later, Moore said she received multiple calls from the doctor’s office telling her to take Maddox to the emergency room because his blood glucose, or blood sugar, level was nearly 700. A normal blood glucose reading for a toddler Maddox’s age is 100 to 180.

“They said I needed to take him to the emergency room right away and my world just stopped,” said Moore. “I can’t imagine had we waited any longer.”

Maddox was diagnosed with Type 1 diabetes and was immediately treated for diabetic ketoacidosis, a potentially life-threatening complication of diabetes that happens when the body doesn’t have enough insulin to allow blood sugar to be used as energy, according to the CDC.

He spent two nights in the hospital and then was sent home, where Moore and her husband are now overseeing Maddox’s regimen of insulin shots and blood glucose monitoring.

“I’m very blessed that he’s as young as he is in a sense because he doesn’t understand and he’s so resilient,” said Moore. “Yes, our lives got turned upside down but he’s happy and he’s doing really well.”

Moore took to Facebook to share what happened to Maddox in hopes of warning other parents to not ignore symptoms their children may be experiencing, like thirst.

“I’m sharing this because what we could’ve written off as being due to warmer weather and being an active toddler literally could’ve killed our son,” she wrote. “Moral of the story, parents, pay attention to your kids and trust your gut. We got very lucky.”

Describing why she spoke out about her family’s experience, Moore told GMA, “My point is not to scare people but just [remind them] to be very aware and keep tracking those things.”

What parents should know

Moore’s Facebook post highlighted how symptoms of Type 1 diabetes can be mistaken for other conditions or overlooked, especially in young children.

“It’s really hard at [Maddox’s] age when he can’t talk,” said Moore. “I fear for the parents who may not be adding things up and having something detrimental happen to their child.”

In addition to excessive thirst, frequent urination and unexplained weight loss, symptoms of Type 1 diabetes can include dry mouth, fatigue and weakness, increased appetite and slow-healing cuts, according to the Juvenile Diabetes Research Foundation, a nonprofit organization focused on research and advocacy for Type 1 diabetes.

Type 1 diabetes, previously called insulin-dependent or juvenile diabetes, is a chronic disease for which there is currently no cure.

It is usually diagnosed in children, teens and young adults, but can develop at any age. Approximately 1.6 million Americans are living with Type 1 diabetes, including about 200,000 people under the age of 20, according to JDRF.

The disease is thought to be caused by an autoimmune reaction that destroys the insulin-making cells in the pancreas, according to the CDC. As a result, people with Type 1 diabetes must remain dependent on insulin, delivered via shots or an insulin pump, to stay alive.

In addition to taking insulin, people with Type 1 diabetes, like Maddox, must measure their blood glucose levels multiple times a day, by either finger pricks or wearing a continuous glucose monitor.

Unlike Type 2 diabetes, which is brought on by lifestyle factors, there is no known way to prevent Type 1 diabetes, according to the CDC. Family history of type 1 diabetes or any other autoimmune disease is commonly seen.

Common complications of Type 1 diabetes include hypoglycemia, or low blood sugar, and diabetic ketoacidosis. Long-term complications from the disease can include increased risk of nerve damage, kidney disease, cardiovascular disease and stroke.

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WHO warns of ‘strong likelihood’ of new, possibly more dangerous variants

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(NEW YORK) — The World Health Organization warned Thursday that the surging COVID-19 pandemic in many parts of the world increases the likelihood that new, potentially dangerous variants may emerge in the future.

“The pandemic is nowhere near finished,” said Professor Didier Houssin, chair of the WHO Emergency COVID-19 Committee.

The global surge in new cases has highlighted the ongoing challenges posed by the pandemic. In Africa, cases surpassed their second wave peak during the seven days ending on July 4 and the death toll this week climbed by 40%, according to WHO.

At the start of the pandemic, there was only one variant of the SARS-CoV-2 virus. As the virus spread across the globe, it mutated, sprouting thousands of new versions of itself — some of which were more contagious than the original.

Currently, there are four variants of concern, labeled by the WHO using the Greek alphabet. The most recent, the delta variant, which was first detected in India, has been identified in more than 111 countries and is now responsible for nearly 60% of all cases in the U.S.

“We expect it to be the dominant strain circulating worldwide, if it isn’t already,” said WHO Director-General Dr. Tedros Adhanom Ghebreyesus.

As the virus continues to spread, new variants might emerge in the future that may be even more challenging to control, the WHO warned.

Vaccines are one of the world’s most important tools to prevent the spread of current SARS-CoV-2 variants, giving the virus less of an opportunity to evolve into new variants. But many countries don’t have enough vaccine supply. Globally, only 25.8% of the world’s population has received at least one dose of a COVID-19 vaccine, according to the University of Oxford’s Global Change Data Lab.

The WHO continued to stress Thursday the importance of leveraging all vaccines currently approved for emergency use and issued a call to action to have at least 10% of every country’s population vaccinated by September 2021.

The WHO encouraged wealthier countries to share vaccine supplies with the rest of the world. Combined with vaccinations, use of evidence-informed public health and social measures, including masks, physical distancing and hand hygiene, remains the most effective strategy for combatting the spread of all SARS-CoV2 variants.

“The virus continues to evolve, resulting in more transmissible variants,” Ghebreyesus said last week, as the world marked four consecutive weeks of rising cases.

Chidimma J. Acholonu, M.D., M.P.H.. is a pediatric resident physician at the University of Chicago and a contributor to the ABC News Medical Unit.

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Surgeon general warns misinformation an ‘urgent threat’ to public health

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(WASHINGTON) — The surgeon general is warning Americans about the “urgent threat of health misinformation” amid the government’s current push to boost stalling vaccination rates.

Dr. Vivek Murthy’s advisory — the first under the Biden administration — addresses an epidemic of misinformation and disinformation, and its pernicious impact on public health — specifically threatening the U.S. response to COVID-19. It frames misinformation as having hindered vaccination efforts, sown mistrust, caused people to reject public health measures, use unproven treatments, prolonged the pandemic and put lives at risk.

The advisory says combatting misinformation is a “moral and civic responsibility” on an individual and institutional level.

The decision to elevate this issue in his first official advisory comes as some Republicans have used the government’s coronavirus response and vaccine messaging as a political wedge.

While Murthy doesn’t call out by name any of the Republican elected officials who have criticized a distorted interpretation of the Biden administration’s vaccine push, he does suggest accountable “stakeholders” in the fight against misinformation include public officeholders as important public messengers.

“Misinformation tends to flourish in environments of significant societal division, animosity, and distrust,” the advisory says. “Distrust of the health care system due to experiences with racism and other inequities may make it easier for misinformation to spread in some communities. Growing polarization, including in the political sphere, may also contribute to the spread of misinformation.”

The advisory also digs into social media platforms as having greatly contributed to the “unprecedented speed and scale” of misinformation’s spread and Murthy calls on technology and social media companies to “take more responsibility to stop online spread of health misinformation.”

“Health misinformation is an urgent threat to public health. It can cause confusion, sow mistrust, and undermine public health efforts, including our ongoing work to end the COVID-19 pandemic,” Murthy said in a statement. “As Surgeon General, my job is to help people stay safe and healthy, and without limiting the spread of health misinformation, American lives are at risk … tackling this challenge will require an all-of-society approach, but it is critical for the long-term health of our nation.”

The advisory lays out how to better identify and avoid sharing health misinformation, engage with the community on the issue and develop local strategies against misinformation:

  • Health professionals and health organizations can proactively engage with patients and the public by listening with empathy and correcting misinformation in personalized ways. The advisory suggests using social media and partnering with community groups to get out accurate information.
  • Governments can prevent and address misinformation by finding “common ground on difficult questions,” increasing investment in research, fact checking and engaging in rumor control. Murthy advised partnering with trusted messengers, using proactive messaging and community engagement strategies. Health teams should identify local misinformation patterns and train public health misinformation researchers.
  • Technology platforms can assess benefits and harms of how their products are built and “take responsibility for addressing the harms;” strengthen their monitoring of misinformation and improve transparency; and proactively address information deficits. The companies could also prioritize early detection of misinformation “super-spreaders” or repeat offenders, and amplify trusted messenger, prioritizing protecting health professionals, journalists and others from online harassment.
  • Journalists and media organizations can make sure their teams are trained in recognizing, debunking and avoiding amplification of misinformation by carefully reviewing materials that have not been peer reviewed.
  • Educators and schools can shore up evidence-based programs that build a “resilience” to misinformation by teaching people how to be more discerning about it and talk to friends and family who are sharing misinformation.
  • Foundations can provide training and resources for grantees working in communities that are disproportionately affected by misinformation, including areas with lower vaccine confidence, and monitoring health misinformation across multiple languages.
  • Researchers and research institutions can strengthen their monitoring of health questions and concerns, assess the impact that misinformation might be having and tailor interventions to the needs of specific populations, with an understanding of how people are exposed to and affected by misinformation.

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Why vaccine incentives may not have been the best answer to hesitancy: Experts

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(NEW YORK) — After more than two months of trying to woo hesitant Americans to get COVID-19 vaccines with cash, free beer and other prizes, health data and experts suggest those incentives failed to move the needle forward appreciably in many cases, and in some had no impact at all.

“A small proportion responds to the incentives, but they are definitely not a panacea,” Dr. Kevin Schulman, a professor of medicine and economics at Stanford University’s School of Medicine and Graduate School of Business, told ABC News of the national vaccine situation.

There was some initial thought that lotteries, in particular, would be effective given their appeal to some people who were also hesitant to get vaccines, experts told ABC News. But since incentives started widely being offered beginning on May 12, the number of first does given in the U.S. briefly increased but then tailed off.

The country did not meet President Joe Biden’s goal of 70% of Americans getting one dose by July 4 and only 48% of the entire population has been fully vaccinated as of July 13, according to data from the U.S. Centers for Disease Control and Prevention (CDC). The situation is more urgent in some states, like Arkansas and Louisiana, where vaccinations levels are below 50% despite well-funded incentive programs.

Schulman and health experts are recommending governors and health officials refocus their efforts on outreach rather than incentivizing if they want to avoid another wave of cases, hospitalization and deaths brought upon by low vaccination numbers.

Ohio’s ‘Vax-a-Million’ — an outlier?

Ohio, the first state to offer a lottery to vaccinated residents, was seen as an early test case. Gov. Mike DeWine used federal stimulus money to offer a $1 million prize and one full college scholarship to teen entrants once a week for five weeks.

One week after the “Vax-a-Million” sweepstakes was announced, an additional 113,000 Ohio residents had received their first dose, according to the state’s health department. That increase represented a week to week 53% jump, the state’s health officials said.

“This exceeded the governor’s expectations,” Dan Tierney, a spokesman for DeWine, told ABC News.

While the state credited the lottery for the jump, there has been no direct study or data to show it was the impetus, aside from some anecdotal evidence, according to the state’s health officials. The data did show that the increase was short-lived.

Since May 12, the number of residents who received their first shot increased by 770,000, according to the Ohio Health Department.

While this represents 13.5% of the 5.7 million Ohio residents who have received their first shot as of July 13, the state only has 48.8% of its population with one dose.

Roughly 55.6% of the total U.S. population has received one dose as of July 13, according to the CDC.

John Brownstein, Ph.D., an epidemiologist at Boston Children’s Hospital and an ABC News contributor, said Ohio’s case demonstrated that vaccine health incentives are really just a stop-gap and true solutions lie in increasing access to a vaccine center and education about efficacy.

“The incentives only really worked for people who were on the fence,” Brownstein said of the Ohio lottery program. “You saw that slight bump, but there are still thousands of people who aren’t signing up and the incentives didn’t work on them.”

Tierney said the Ohio lottery campaign organizers acknowledged that the campaign was most effective at convincing residents who were planning on getting vaccinated but held out due to scheduling time around school, work or vacations.

But Tierney also maintained that those hundreds of thousands of newly vaccinated residents still make a difference in the state’s goal.

“I think Vax-a-Million forced a lot of people to think about their calculations about when they wanted to get the vaccine,” he said.

Others lagging behind

Brownstein and health experts warned that Ohio’s increase following its lottery was an outlier.

Eighteen other states, including Maryland and New York, came up with their own vaccine lotteries or cash giveaways following Ohio, according to the National Governor’s Association. Their combined efforts appeared to only make a small and short-lived dent in vaccination numbers.

The seven-day average of new first doses given initially climbed from 1.79 million on May 12 after the states offered their programs to 1.88 million a week later but has steadily declined to 421,000 on July 7, according to the data. The average peaked at 3.4 million doses on April 11, according to the CDC.

Several states with already lagging vaccine numbers saw no jump after their programs were announced, according to health data.

In Louisiana, where only 39% of the entire population has one dose of the vaccine, the seven-day average of new daily doses administered has remained level at around 10,000 for the last month, according to Louisiana Health Department. A lottery for vaccinated residents was announced on June 17.

In Arkansas, the seven-day average of new vaccine shots administered declined by over 3,500 after the state announced its scratch-off game incentive for vaccinated residents on May 25, according to the Arkansas Health Department.

“I don’t know if we’re going to be able to buy our way out of this,” Col. Robert Ator, the program director of the Arkansas vaccine incentive program, told ABC affiliate KATV on June 28.

A representative for the Arkansas Health Department told ABC News the state is looking at other options including a request to businesses to offer incentives to people.

Don’t focus on incentives: Experts

Schulman co-authored a report in the New England Journal of Medicine in January arguing that the best ways to promote the COVID-19 vaccination among the populace is for state leaders to rethink their approaches and focus on marketing rather than rewards

Specifically, Schulman said states should prepare and launch marketing and advertising campaigns aimed at Americans who think it’s OK not to get a shot because hospitalizations and deaths are down from the winter and they’ll be fine.

“They are a really important group to address now. They’re more likely to respond to a good marketing campaign,” he said.

Informing those unvaccinated members about the dangers of the virus, particularly the growing threat of variants, and the effects on their families and businesses will go a longer way than a cash prize, Schulman argued.

“I would go back to those lottery states and ask how much did you spend on the lottery and how much could you have spent on Facebook ads that could appeal to those populations,” he said.

Tierney noted that the Vax-a-Million sweepstakes generated a form of publicity for the vaccine because of news articles, social media posts and word of mouth. His office has estimated that the coverage was the equivalent of $50 million in advertising.

“We could not have bought this word of mouth,” he said.

Schulman said it is promising that state leaders are working to close the vaccination gap, but reiterated that they’ll need more precise targeting to pick up the pace.

“The fact that these governors sounded the alarm early and said, ‘We have a problem,’ is encouraging,” he said. “They must not give up.”

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Mississippi health officials warn about delta ‘surge’ as 7 children in ICU due to COVID-19

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(JACKSON, Miss.) — As the delta variant spreads rapidly across the U.S., Mississippi officials are warning about hospitalizations of children with severe cases of COVID-19.

Of the seven children currently in the intensive care unit due to COVID-19, two are on ventilators, according to State Health Officer Dr. Thomas Dobbs.

“Delta Surge – be careful,” Dobbs said in a terse tweet Tuesday, while sharing the updates on the latest hospitalizations.

Dobbs initially said 12 children statewide were in the ICU due to COVID-19, though later revised that to a smaller number after a hospital corrected its report.

“Please be safe and if you are 12 or older – please protect yourself,” he said.

The ages ranged from under 1 to 17, Dobbs said in a statement to ABC News Wednesday.

Children are less likely than adults to have serious COVID-19 infections. Most have mild symptoms, if any, according to the Centers for Disease Control and Prevention, though in rare instances, they have developed severe cases that led to hospitalization or death.

It is not clear if any of the seven chilidren have underlying health conditions that would put them at greater risk for severe illness from COVID-19.

Dr. Alan Jones, associate vice chancellor for clinical affairs at the University of Mississippi Medical Center in Jackson, told ABC News Wednesday that his facility was seeing a “significant increase” in pediatric patients over the last several weeks.

The medical center is currently treating five children with confirmed COVID-19 cases, two of whom are in the ICU. Two other children at the hospital are being investigated for potential COVID-19 infections, he said.

The children, who are in stable condition, range from infants to teenagers, Jones said. He could not share any further details about the cases but said that many patients within his hospital who are currently in the ICU do have some chronic, underlying comorbidity diseases that would put them at a higher risk of having a more severe illness associated with COVID-19.

The state has been seeing a “pretty alarming” increase in the number of COVID-19 cases and hospitalizations, Dobbs said during a press briefing last Friday, as the highly contagious delta variant, which was initially identified in India, has quickly become the dominant variant in the state.

“We have seen pretty much an entire takeover of the delta variant for our transmission,” Dobbs said during the briefing, noting that the current cases in the state are “pretty much all delta.”

Between June 15 and July 9, the delta variant accounted for 80% of all specimens sequenced in the state, according to Dobbs.

Hospital systems are not currently overwhelmed, but Dobbs said there are “concerns about it going forward, as has been seen in other states” due to delta, which has become the dominant variant nationwide.

Mississippi’s daily COVID-19 case average has more than doubled in the last three weeks. Less than three weeks ago, there were under 100 patients receiving care for COVID-19 in Mississippi. As of July 11, there were nearly 200. Hospital admissions have also increased by 26.7% in the last week.

The state has seen an increase in COVID-19 outbreaks as well, particularly among youth, in summer activities and nursing homes, Dobbs said.

Jones said his hospital’s pediatric patients seem to be more symptomatic than the children who became ill earlier in the pandemic, which he attributed to the delta variant.

“These seem to be more classic COVID symptoms — fever, cough, respiratory illness,” he said. “I suspect that’s probably because this delta variant is importing a little more severe illness in the pediatric population than those earlier strains that were circulating.”

The delta variant is surging as Mississippi has the second-lowest vaccination rate in the country, with approximately one-third of the state’s total population fully vaccinated, according to the CDC. The “vast majority” of cases, hospitalizations and deaths in the state now are in unvaccinated people, Dobbs said.

Due to the low vaccination rate, the state health department advised Friday that those who are ages 65 and older or have chronic medical conditions avoid mass indoor gatherings for several weeks.

“Our collective under-vaccination in the state has put us all at risk, especially the most vulnerable,” Dobbs said.

Editor’s Note: A state health officer has issued a correction revising the number of children hospitalized with severe COVID-19 cases from 12 to seven.

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Delta variant now accounts for about 58% of COVID-19 cases in US, CDC says

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(NEW YORK) — A highly contagious variant of the novel coronavirus that was initially identified in India now accounts for about 58% of all COVID-19 cases in the United States, according to the Centers for Disease Control and Prevention.

Data updated by the CDC on Tuesday evening shows the so-called delta variant, also known as B.1.617.2, was estimated to be responsible for 57.6% of newly confirmed cases nationwide from June 20 through July 3. The proportion was estimated at just 31.1% for the two weeks prior.

In late May, the delta variant was estimated to account for approximately 3% of new cases in the U.S, according to CDC data.

After being initially identified in India in October, the delta variant has since been reported in at least 104 countries around the globe and is expected to soon be the dominant coronavirus variant circulating worldwide, according to the World Health Organization. The variant was first detected in the U.S. in March and is now present in all 50 states.

“The delta variant is ripping around the world at a scorching pace, driving a new spike in cases and death,” WHO Director-General Tedros Adhanom Gebreyesus said during a COVID-19 press briefing on Monday.

Last week marked the fourth consecutive week that the number of newly confirmed COVID-19 cases has increased globally. Deaths are also on the rise again after 10 weeks of decline, according to Tedros, who noted that the WHO has received reports from all regions of the world about hospitals reaching capacity.

“In places with high vaccination coverage, Delta is spreading quickly; especially infecting unprotected and vulnerable people and steadily putting pressure back on health systems,” he said. “In countries with low vaccine coverage, the situation is particularly bad.”

The WHO declared delta a “variant of concern” in May, and the CDC upgraded its classification of the strain in June from “variant of interest” to a “variant of concern.” Both the WHO and the CDC say that variants of concern have shown to be both more infectious and more virulent than other strains.

The delta variant has shown to be particularly dangerous to those who are unvaccinated or partially vaccinated against COVID-19, and preliminary data indicates it may increase the risk of hospitalization.

However, current evidence suggests that the full dosage of a COVID-19 vaccine is highly effective in preventing hospitalizations and serious illness. Instances where a fully vaccinated individual becomes infected with COVID-19, known as breakthrough cases, are exceedingly rare. And while early laboratory studies indicated the vaccines seem to produce far fewer virus-fighting antibodies against some of the newer variants, real-world experience tells a different story as researchers across the globe learn that the vaccines still mostly work — even when those antibodies fail to show up in great numbers — thanks to other crucial parts of the body’s immune system.

Still, there is very little known about the mutating virus and it remains unclear exactly how long immunity from the vaccines will last and whether booster shots will be needed to maintain protection.

As delta and other highly transmissible variants spur “catastrophic waves” of COVID-19 infections, the WHO director-general is urging vaccine manufacturers to prioritize supplying doses to poorer countries with low vaccination rates rather than giving booster shots to wealthier nations with relatively high coverage.

“The global gap in vaccine supply is hugely uneven and inequitable,” Tedros said Monday. “Some countries and regions are actually ordering millions of booster doses, before other countries have had supplies to vaccinate their health workers and most vulnerable.”

Since the start of the pandemic, the U.S. has reported more than 33.9 million confirmed cases of COVID-19 and over 607,000 deaths from the disease, according to data collected by Johns Hopkins University. The U.S. has recorded the highest death toll, while India has the highest total case count.

More than 184 million people in the U.S. have received at least one dose of a COVID-19 vaccine, including over 159 million — 48.1% of the population — who are fully vaccinated, according to CDC data.

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Mississippi health officials warn about delta ‘surge’ as 12 children in ICU due to COVID-19

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(JACKSON, Miss.) — As the delta variant spreads rapidly across the country, Mississippi officials are warning that a dozen children are hospitalized throughout the state with severe cases of COVID-19.

Of the 12 children currently in the intensive care unit due to COVID-19, 10 are on ventilators, according to State Health Officer Dr. Thomas Dobbs.

“Delta Surge – be careful,” Dobbs said in a terse tweet Tuesday, while sharing the updates on the latest hospitalizations.

Children are less likely than adults to have serious COVID-19 infections. Most have mild symptoms, if any, according to the Centers for Disease Control and Prevention, though in rare instances, they have developed severe cases that led to hospitalization or death.

It is not clear what the ages of the 12 children are, if they were eligible for the COVID-19 vaccine or if any have underlying health conditions that would put them at greater risk for severe illness from COVID-19. ABC News has reached out to the Mississippi Department of Health for more information on the cases.

Dr. Alan Jones, associate vice chancellor for clinical affairs at the University of Mississippi Medical Center, told ABC affiliate WAPT in Jackson, Mississippi, that his facility is currently treating four pediatric COVID-19 patients, two of whom are on ventilators.

“We have had more pediatric admissions than we had early in the pandemic,” Jones told the station.

The state has been seeing a “pretty alarming” increase in the number of COVID-19 cases and hospitalizations, Dobbs said during a press briefing last Friday, as the highly contagious delta variant, which was initially identified in India, has quickly become the dominant variant in the state.

“We have seen pretty much an entire takeover of the delta variant for our transmission,” Dobbs said during the briefing, noting that the current cases in the state are “pretty much all delta.”

Hospital systems are not currently overwhelmed, but Dobbs said there are “concerns about it going forward, as has been seen in other states” due to delta, which has become the dominant variant nationwide.

Mississippi’s daily COVID-19 case average has more than doubled in the last three weeks. Less than three weeks ago, there were under 100 patients receiving care for COVID-19 in Mississippi. As of July 11, there were nearly 200. Hospital admissions have also increased by 26.7% in the last week.

The state has seen an increase in COVID-19 outbreaks as well, particularly among youth, in summer activities and nursing homes, Dobbs said.

The delta variant is surging as Mississippi has the second-lowest vaccination rate in the country, with approximately one-third of the state’s total population fully vaccinated, according to the CDC. The “vast majority” of cases, hospitalizations and deaths in the state now are in unvaccinated people, Dobbs said.

Due to the low vaccination rate, the state health department advised Friday that those who are ages 65 and older or have chronic medical conditions avoid mass indoor gatherings for several weeks.

“Our collective under-vaccination in the state has put us all at risk, especially the most vulnerable,” Dobbs said.

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