Health

(NEW YORK) — More measles cases are being confirmed across the United States as health officials work to treat patients in an ongoing outbreak in Texas.

The Kentucky Department for Public Health (KDPH) and the Franklin County Health Department announced on Wednesday a confirmed case of measles in an adult resident, the first in the state in two years.

The departments said the resident recently traveled internationally to an area where measles is spreading.

Meanwhile, in New Jersey, health officials confirmed two new measles cases in Bergen County linked to a patient whose case was confirmed earlier this month.

Officials haven’t found any links between the cases in Kentucky and New Jersey, and there’s no evidence the cases in Kentucky or New Jersey are connected to the outbreak in Texas, which has so far sickened 124 people and led to one death in an unvaccinated school-aged child.

Kentucky health officials are now attempting to contact anyone the infected resident may have come into contact with. The resident attended a Planet Fitness in Frankfort on Feb. 17 while contagious, officials said.

“Measles is one of the most contagious viruses in the world,” KDPH Commissioner Dr. Steven Stack said in a statement. “Fortunately, measles can be prevented with the measles, mumps and rubella (MMR) vaccine, which is safe and effective. Vaccines are an essential tool to keep children and adults safe and healthy.”

An official briefed on the situation told ABC News on Thursday that the new cases in New Jersey are members of the same family and were not vaccinated. Because they are in the same family, public health officials are hopeful public spread will have been limited.

The original case tested positive after traveling internationally. The New Jersey Department of Health said people may have been exposed to measles if they visited Englewood Hospital’s Emergency Department on Feb. 5.

Health officials said people who were exposed could develop symptoms until as late as March 6.

Measles is one of the most contagious diseases known to humans. Just one infected patient can spread measles to up to nine out of 10 susceptible close contacts, according to the Centers for Disease Control and Prevention.

Health officials have been urging anyone who isn’t vaccinated to receive the measles, mumps, rubella (MMR) vaccine.

The CDC currently recommends that people receive two vaccine doses, the first at ages 12 to 15 months and the second between 4 and 6 years old. One dose is 93% effective, and two doses are 97% effective. Most vaccinated adults don’t need a booster.

Measles was declared eliminated from the U.S. in 2000 due to the highly effective vaccination program, according to the CDC. However, CDC data shows vaccination rates have been lagging in recent years.

ABC News’ Matt Foster contributed to this report.

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(NEW YORK) — Longer periods of extreme heat has been found to accelerate biological age in older adults by up to two years, according to new research.

More heat days over time correlated with deterioration at the molecular and cellular level in adults 56 years or older, likely because the biological deterioration accumulates over time and eventually leads to disease and disability, Eunyoung Choi, a postdoctoral associate at the University of California’s Leonard Davis School of Gerontology, told ABC News.

Researchers at the University of Southern California studied blood samples from 3,686 adults starting at an average chronological age of 68 years with varying socioeconomic backgrounds across the U.S. and compared epigenetic aging trends to the number of extreme heat days in the participants’ places of residence, according to a study published Wednesday in Science Advances.

“Epigenetic age is one way we measure biological aging, which tells us how well our body is functioning at the physical, molecular and the cellular levels,” Choi said. “…We know that some people seem to age faster than others, and that’s because biological aging doesn’t always match chronological age.”

Regression modeling showed that more heat days, or longer-term heat, over one and six years increased biological age by 2.48 years. Short and mid-term heat also increased biological age by 1.07 years, according to the paper.

Extreme heat was defined as the daily maximum heat index — derived from both temperature and humidity — with a “caution” range of between 80 degrees to 90 degrees Fahrenheit and an “extreme caution” range of between 90 degrees and 103 degrees Fahrenheit, in accordance with the National Weather Service, according to the paper. “Extreme danger” was defined as any heat index level over 124 degrees Fahrenheit.

The researchers compared the epigenetic age of participants from regions with long periods of extreme heat to those living in cooler climates. There was a 14-month difference in epigenetic age between residents living in places like Phoenix, Arizona, than milder places like Seattle, even after accounting other individual and community-level differences, like income, education, physical activity and smoking, Choi said.

“Two people that had identical sociodemographic characteristics and similar lifestyles, just because one is living in a hotter environment, they experience additional biological aging,” she said.

The 14-month differences is comparable to effects seen with smoking and heavy alcohol consumption — two well-established risk factors of accelerated biological aging, the researchers found.

DNA methylation — the process of chemical modification to DNA that tends to change as people age — is “highly responsive” to environmental exposures like social stress, pollution and, in this case, extreme heat, Choi said.

Previous research has linked extreme heat to serious health risks like cardiovascular disease, kidney dysfunction, hospitalization and even death, Choi said. But prior to this research, scientists did not fully understand what is occurring at the biological level before those health issues appear, Choi added.

“The physical toll of the heat might not show up right away as a diagnosable health condition, but it could be taking a silent toll at the cellular and the molecular level,” Choi said.

It’s important to uncover potential hidden effects of heat on the body because it can serve as an “important precursor” before they turn into more serious health conditions, Choi said.

“We can intervene at the earlier stage,” she added.

Humidity also plays a big role in how the body responds to heat, especially for older adults, Choi said.

“As we age, our bodies don’t cool down as rapidly,” she said.

The new research provides a foundation for the development of targeted public health interventions, the researchers said.

“This provides strong evidence critical for guiding public policy and advocacy initiatives aimed at developing mitigation strategies against climate change,” Choi said.

ABC News Medical Unit’s Dr. Jessica Yang contributed to this report.

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(LUBBOCK, Texas) — An unvaccinated school-aged child in Texas has died of measles, the first associated with an outbreak in the western part of the state that has infected more than 100 people.

Lubbock city spokesperson Lauren Adams confirmed the death to ABC News on Wednesday.

In a press release, the Texas Department of State Health Services (DSHS) said the child was hospitalized in the northwestern city of Lubbock last week and tested positive for measles.

As of Wednesday, 124 cases of measles have been confirmed associated with the outbreak, according to data from DSHS.

Almost all of the cases are in unvaccinated individuals or individuals whose vaccination status is unknown, and 18 people have been hospitalized so far, DSHS said.

Children and teenagers between ages 5 and 17 make up the majority of cases with 62, followed by 39 cases among children ages 4 and under.

The outbreak began in Gaines County, which has become the epicenter, with 80 cases confirmed among residents, according to DSHS.

The outbreak has since spread to several counties in the region and is “suspected” to have spread into New Mexico, according to New Mexico Department of Health (NMDOH). Nine cases have been confirmed in Lea County, which borders Texas. Of the nine cases, four are among children, according to NMDOH.

“This death underscores the real danger of measles — it’s a severe disease that can take lives despite being preventable with vaccination,” said Dr. John Brownstein, an epidemiologist and ABC News contributor. “Every new case is a reminder of why vaccination is critical. Tragically, with an outbreak of this scale, a fatal case was not unexpected, especially among those unvaccinated. Given how contagious measles is, we anticipate more cases in the coming weeks.”

During Tuesday’s Cabinet meeting, Health and & Human Services Secretary Robert F. Kennedy Jr. responded to a question about the outbreak, saying the agency was following the cases in Texas.

Kennedy appeared to downplay the outbreak, noting there have been four outbreaks so far this year compared to 16 last year. However, the number of cases in Texas alone amount to nearly half of the 285 cases confirmed in 2024.

“It’s not unusual; we have measles outbreaks every year,” he said.

Measles is one of the most contagious diseases known to humans. Just one infected patient can spread measles up to nine out of 10 susceptible close contacts, according to the Centers for Disease Control and Prevention (CDC).

Health officials have been urging anyone who isn’t vaccinated to receive the measles, mumps, rubella (MMR) vaccine.

The CDC currently recommends people receive two vaccine doses, the first at ages 12 to 15 months and the second between 4 and 6 years old. One dose is 93% effective, and two doses are 97% effective. Most vaccinated adults don’t need a booster.

Measles was declared eliminated from the U.S. in 2000, due to the highly effective vaccination program, according to the CDC. However, vaccination rates have been lagging in recent years.

About 93% of kindergarteners nationwide received select routine childhood vaccines, including the MMR vaccine, for the 2022-23 school year, according to a November 2023 CDC report.

This is about the same as the previous school year, but lower than the 94% seen in the 2020-22021 school year and the 95% seen in the 2019-2020 school year, prior to the COVID-19 pandemic. The latter percentage had been the standard for about 10 years.

ABC News’ Youri Benadjaoud contributed to this report.

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(LUBBOCK, Texas) — An unvaccinated school-aged child in Texas has died of measles, the first associated with an outbreak in the western part of the state that has infected more than 100 people.

Lubbock city spokesperson Lauren Adams confirmed the death to ABC News on Wednesday.

In a press release, the Texas Department of State Health Services (DSHS) said the child was hospitalized in the northwestern city of Lubbock last week and tested positive for measles.

As of Wednesday, 124 cases of measles have been confirmed associated with the outbreak, according to data from DSHS.

Almost all of the cases are in unvaccinated individuals or individuals whose vaccination status is unknown, and 18 people have been hospitalized so far, DSHS said.

Children and teenagers between ages 5 and 17 make up the majority of cases with 62, followed by 39 cases among children ages 4 and under.

The outbreak began in Gaines County, which has become the epicenter, with 80 cases confirmed among residents, according to DSHS.

The outbreak has since spread to several counties in the region and is “suspected” to have spread into New Mexico, according to New Mexico Department of Health (NMDOH). Nine cases have been confirmed in Lea County, which borders Texas. Of the nine cases, four are among children, according to NMDOH.

“This death underscores the real danger of measles — it’s a severe disease that can take lives despite being preventable with vaccination,” said Dr. John Brownstein, an epidemiologist and ABC News contributor. “Every new case is a reminder of why vaccination is critical. Tragically, with an outbreak of this scale, a fatal case was not unexpected, especially among those unvaccinated. Given how contagious measles is, we anticipate more cases in the coming weeks.”

Measles is one of the most contagious diseases known to humans. Just one infected patient can spread measles up to nine out of 10 susceptible close contacts, according to the Centers for Disease Control and Prevention (CDC).

Health officials have been urging anyone who isn’t vaccinated to receive the measles, mumps, rubella (MMR) vaccine.

The CDC currently recommends people receive two vaccine doses, the first at ages 12 to 15 months and the second between 4 and 6 years old. One dose is 93% effective, and two doses are 97% effective. Most vaccinated adults don’t need a booster.

Measles was declared eliminated from the U.S. in 2000, due to the highly effective vaccination program, according to the CDC. However, vaccination rates have been lagging in recent years.

About 93% of kindergarteners nationwide received select routine childhood vaccines, including the MMR vaccine, for the 2022-23 school year, according to a November 2023 CDC report.

This is about the same as the previous school year, but lower than the 94% seen in the 2020-22021 school year and the 95% seen in the 2019-2020 school year, prior to the COVID-19 pandemic. The latter percentage had been the standard for about 10 years.

ABC News’ Youri Benadjaoud contributed to this report.

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(LUBBOCK, Texas) — An unvaccinated school-aged child in Texas has died of measles, the first associated with an outbreak in the western part of the state that has infected more than 100 people.

Lubbock city spokesperson Lauren Adams confirmed the death to ABC News on Wednesday.

In a press release, the Texas Department of State Health Services (DSHS) said the child was hospitalized in Lubbock, located in northwestern Texas, last week and tested positive for measles.

As of Wednesday, 124 cases of measles have been confirmed, according to data from DSHS.

Almost all of the cases are in unvaccinated individuals or individuals whose vaccination status is unknown, and 18 people have been hospitalized so far, DSHS said.

Children and teenagers between ages 5 and 17 make up the majority of cases with 62, followed by 39 cases among children ages 4 and under.

This is a developing story. Please check back for updates.

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(DEMOCRATIC REPUBLIC OF CONGO) — The World Health Organization has reported that there is a deadly “unknown disease” spreading in one region within the Democratic Republic of Congo.

Local health officials in Congo are partnering with the World Health Organization to investigate.

The phrase “unknown disease” primarily means that the disease has not yet been identified.

In previous cases, the cases are linked to a known disease, but a lack of available testing leads to lack of certainty.

For example, there was a separate report of an “unknown disease” in December of last year in Congo that was later attributed to illnesses from malaria and respiratory illnesses.

The latest numbers from the WHO’s Africa Region show that there are 431 cases linked to the outbreak and 53 deaths since January.

Early investigations traced the outbreak’s origin to three kids, all under 5 years old, who developed symptoms after eating a bat carcass.

Symptoms included fever, headache, diarrhea and fatigue – which later progressed to signs associated with hemorrhagic fevers and death.

Ebola and Marburg have already been ruled out, officials say. Nearly half of deaths occurred within 48 hours after symptoms start.

“The remote location and weak healthcare infrastructure increase the risk of further spread,” the WHO notes in its report.

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(WASHINGTON) — The Centers for Disease Control and Prevention (CDC) said on Monday that the new coronavirus found in bats is currently not a cause for concern.

There is no reason to believe the virus poses a threat to public health at the moment and no infections have been detected in humans, according to the federal health agency.

“CDC is aware of a publication about a new bat coronavirus, but there is no reason to believe it currently poses a concern to public health,” the agency said in a statement. “The publication referenced demonstrates that the bat virus can use a human protein to enter cells in the laboratory, but they have not detected infections in humans.”

Chinese researchers, including from the Wuhan Institute of Virology and Guangzhou Medical University, published a paper in the journal Cell on Friday indicating they had discovered a new bat coronavirus that could have the potential to infect humans.

The newer coronavirus is known as HKU5-CoV-2 and is a type of merbecovirus, which is the same family of another coronavirus known to infect humans called Middle East Respiratory Syndrome (MERS).

In a lab study, the new coronavirus was found to have the potential to enter cells through the ACE2 receptor, a protein found on the cells’ surface.

This is the same way the virus that causes COVID-19 infects people, which theoretically means the new coronavirus could pose a risk to spilling over into humans.

The spike protein of the new coronavirus infected human cells that had high levels of the ACE2 receptor in test tubes, as well as in small models of human airways and intestines.

The researchers found that the virus did not enter human cells as readily as the virus that causes COVID-19 — which is called SARS-CoV-2 — writing that the “risk of emergence in human populations should not be exaggerated.”

None of the animal studies that were conducted examined the virus’s ability to cause disease or its transmissibility.

If the virus were to infect humans, the researchers suggested antiviral drugs and monoclonal antibodies — laboratory-produced proteins that mimic the antibodies the body naturally creates when fighting a virus — could be effective.

There are hundreds of coronaviruses circulating in nature. Only a few can infect humans, causing illnesses ranging from mild respiratory tract infections to more severe conditions such as bronchitis or pneumonia.

Coronaviruses include some variations of the common cold, the virus that causes MERS, severe acute respiratory syndrome (SARS) and the virus that causes COVID-19.

The researchers wrote that “bats harbor the highest proportion of genetically diverse coronaviruses,” posing a risk of spilling over into humans.

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(NEW YORK) — Flu activity remains “elevated” in the United States but is starting to show signs of abating, according to new federal data published Friday.

The 2024-25 flu season was classified by the Centers for Disease Control and Prevention (CDC) as a “high” severity season overall and for all age groups, making it the first high severity season since 2017-2018.

During the week ending Feb. 15, 6.8% of visits to doctors’ offices were for flu-like illness, down from 7.7% of visits over the previous two weeks, CDC data shows.

Emergency department visits for flu also fell to 6.4% during the week ending Feb. 15 from more than 8% for the two weeks prior.

Additionally, 26.9% of tests came back positive for flu during the week ending Feb. 15. This is higher than the peak of 18.2% last flu season but lower than the 31.4% recorded over the previous two weeks.

The CDC estimates there have been at least 33 million illnesses, 430,000 hospitalizations and 19,000 deaths from flu so far this season

At least 86 pediatric flu deaths have been recorded so far, with 18 reported the week ending Feb. 15.

It comes as overall respiratory illness activity is listed as “high” nationwide, CDC data shows.

As of Friday, nine states are listed as having “very high” levels of respiratory virus activity and 14 states are listed as “high.” The remaining states are listed as having “moderate” or “low” levels.

Comparatively, 12 states were listed as “very high” and 20 states were listed as “high” last week.

Meanwhile, although COVID-19 activity is “elevated” in many areas of the U.S., CDC data shows emergency department visits are at low levels and the number of laboratory tests coming back positive is stable.

Respiratory syncytial virus activity was also described as “elevated” but declining in most areas of the U.S., according to the CDC.

Public health experts have recommended children and adults receive the flu and COVID vaccine as well as older adults receive the RSV vaccine, but coverage is “low,” according to the CDC.

As of Feb 8, only 45.3% of adults were vaccinated against the flu and 23,1% were vaccinated with the updated 2024-25 COVID-19 vaccine. Additionally, just 46.7% of adults ages 75 and older have received the RSV vaccine, according to CDC data.

Nearly half of all children are vaccinated against the flu at 45.8%, but just 12.1% have received the updated COVID-19 vaccine.

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(AUSTIN, Texas) — The number of measles cases linked to an outbreak in western Texas has grown to 90, according to new data released on Friday.

Almost all of the cases are in unvaccinated individuals or individuals whose vaccination status is unknown, and 16 people have been hospitalized so far, according to the Texas Department of State Health Services. Five cases included those who have been vaccinated.

A DSHS spokesperson previously told ABC News that this marks the largest measles outbreak in the state in more than 30 years.

Children and teenagers between ages 5 and 17 make up the majority of cases with 51, followed by 26 cases among children ages 4 and under.

Gaines County is the epicenter of the outbreak, with 57 cases confirmed among residents, according to DSHS. State health data shows the number of vaccine exemptions in the county have grown dramatically.

Roughly 7.5% of kindergarteners had parents or guardians who filed for an exemption for at least one vaccine in 2013. Ten years later, that number rose to more than 17.5% — one of the highest in all of Texas, according to state health data.

Meanwhile, in neighboring New Mexico, at least nine cases have been confirmed in Lea County, which borders Texas, a spokesperson for the state Department of Health told ABC News on Friday.

The Centers for Disease Control and Prevention has separately confirmed 14 cases in five states so far this year, which does not include the recent Texas or New Mexico cases or recently confirmed cases in Georgia.

Similarly to the local outbreaks, all of the nationally confirmed cases are in people who are unvaccinated or whose vaccination status is unknown.

Measles is one of the most contagious diseases known to humans. Just one infected patient can spread measles up to nine out of 10 susceptible close contacts, according to the CDC.

Health officials have been urging anyone who isn’t vaccinated to receive the measles, mumps, rubella (MMR) shot.

The CDC currently recommends people receive two vaccine doses, the first at ages 12 to 15 months and the second between 4 and 6 years old. One dose is 93% effective, and two doses are 97% effective.

In the decade before the measles vaccine became available, an estimated 3 to 4 million people were infected every year, according to the federal health agency.

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(NEW YORK) — A personalized mRNA vaccine may reduce the risks of pancreatic cancer returning after surgery, according to a preliminary study published Wednesday in the journal Nature.

Pancreatic cancer is one of the most aggressive cancers, with a typical survival rate of only about a year after the diagnosis according to the study.

While the findings are encouraging, the vaccine is still in early testing and will likely take years before it becomes widely available — assuming ongoing trials continue to show success, according to Dr. Vinod P. Balachandran, lead investigator of the trial and senior author of the study.

In this small, preliminary trial of 16 patients, half had a strong immune response to the vaccine. Most of these responders remained cancer-free for more than three years, much longer than those who didn’t respond.

The vaccine works by training specialized immune system cells, known as T cells, to recognize and attack the cancer.

Researchers couldn’t track tumor shrinkage because all patients had surgery to remove visible cancer before vaccination. However, they found that the vaccine produced long-lasting T cells that may keep fighting cancer for years.

“This is one way through which you can make lots of T cells, and you can make these T cells such that they can persist for a long time in patients and retain their function,” Balachandran said.

Balachandran said “to be able to get an immune response has been very challenging,” especially when an illness like pancreatic cancer typically does not respond to vaccines, which highlights the significance of these findings.

A larger trial is now underway to confirm the results. If successful, this approach could lead to new ways to treat or even prevent pancreatic and other advanced cancers.

Overall, Balachandran said this study can “provide some important clues on how you would be able to develop vaccines more broadly for other cancers.”

“Hopefully this information that we will learn from these clinical trials will give us information to know apply vaccines in other settings, such as primary prevention, meaning preventing cancers from occurring even before they occur, with vaccines or perhaps also using it to treat patients who have more advanced disease,” Balachandran said.

-Suhas Kochat, MD, contributed to this report

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