More Black physicians could improve life expectancy of Black patients: Researchers

More Black physicians could improve life expectancy of Black patients: Researchers
More Black physicians could improve life expectancy of Black patients: Researchers
Courtesy Wilson Hayes

(NEW YORK) — Weeks of shoulder pain landed a reluctant Whitney Nichols in urgent care. As a previously healthy 24-year-old Black woman, she pleaded for additional testing to uncover the cause of her pain. As a last resort, the doctor ordered a CT scan of her chest. The result, blood clots in both of her lungs.

Even after this seemingly scary diagnosis and after being transferred to a hospital, Nichols said she felt dismissed when a doctor told her she would be fine.

Nichols, now 29 and a graduating medical student, reflected that these interactions with dismissive doctors made her feel “so alone in that space” and unsafe.

But Nichols said that night, everything changed when a Black physician, Dr. Erika Walker, walked into the room. Walker explained the blood clots were serious but treatable. Walker advised Nichols to stop taking her estrogen-based birth control, which can increase the risk of blood clots, and prescribed medication that would break up the clots.

She said it was great ” … just seeing somebody that I felt like I could be comfortable with.”

Black people make up 13% of the U.S. population, but Black doctors are not equally represented. For example, only 7% of primary care physicians are Black, according to a study from the Journal of the American Medical Association. Amid a growing recognition that Black Americans experience disparities in health and medical care, new research suggests that Black patients are more likely to live longer and healthier lives when their primary care doctors are also Black.

Michael Dill, director of Workforce Studies at the Association of American Medical Colleges team, analyzed the relationship of Black primary care physicians and the health outcome of the people who lived in those same areas, evaluating 1,600 U.S. counties. Dill and his colleagues found that a 10% increase in Black primary care doctor representation was associated with an extra month of life expectancy for Black patients.

The higher the representation of black physicians in the workforce per county was associated less death of any cause for county residents, Black and White patients. Thus, even people not actively being treated by Black physicians benefitted from their presence like the results published in the Journal of the American Medical Association in April of 2023.

“We found that diversifying the physician workforce … is important for improving public health,” Dill told ABC News.

Dr. Bobby Mukkamala, past chair of the American Medical Association Board of Trustees, said the data was “shocking” but “in a motivational way.” Mukkamala said this data can be used to advocate for equitable hiring practices at hospitals and health care systems so that doctors and staff look like the communities they serve.

Researchers said when doctors have similar cultures and lived experiences to the patients, they may be more likely to take their concerns seriously, which results in better life expectancy.

For over 150 years ago, Historically Black Colleges and Universities (HBCU) were established to provide Black students the opportunities to advance their education when they were unwelcome at existing public and private institutions of higher education. Traditionally HBCUs are a large producer of Black physicians.

Dr. Erica Sutton, associate dean at Morehouse School of Medicine said, “feeling heard, perhaps listening as well, and then translating that into patient centered care patient driven treatment plans,” is the essence of why Black physicians can impact their patients’ health.

Dill said there is no shortcut to increasing workforce diversity. “This is not a problem we can fix in a couple of years,” Dill said. “This is the work of generations.”

Mukkamala, Sutton, and Whitney are involved in programs that aim to increase and inspire young children of diverse backgrounds to pursue careers in science, education, technology and math, including The American Medical Association’s Back to School Program, Morehouse’s health careers programs and Student National Medical Association.

“This isn’t something that you can tell somebody in college to convince them to [pursue medicine],” Mukkamala told ABC News. “Those seeds get planted early on in grade school.”

Sutton is hopeful for the future.

“I think that one of the things that we’ve seen recently in this country is a renewed interest in inclusivity belongingness … we definitely try to teach at HBCUs is that these [less diverse] communities do include you,” Sutton told ABC News. “It’s not us and them…that community is enriched by your presence.”

Danielle Craigg, MD is a senior General Preventive Medicine & Public Health Resident at Renaissance School of Medicine at Stony Brook University and a member of the ABC News Medical Unit.

Sotonye Douglas, MS is a graduating medical student from Quinnipiac University, Frank H Netter Medical School, beginning General Surgery Residency in June 2023, and a member of the ABC News Medical Unit.

Copyright © 2023, ABC Audio. All rights reserved.

New report details alarming health impact of climate change on children

New report details alarming health impact of climate change on children
New report details alarming health impact of climate change on children
Mimi Haddon/Getty Images

(NEW YORK) — A new report released this week by the Environmental Protection Agency projects the devastating health impact of climate change on children.

Effects include higher rates of respiratory disease, reduced academic achievement, higher rates of infections and risk of housing insecurity in coastal cities.

“Children have unique vulnerabilities,” Jeremy Martinich, chief of EPA’s Science and Impacts Branch and a co-author of the report, told ABC News. “This report is really intended to provide a new level of specificity about some of these risks.”

One major risk is extreme heat waves, which can have a negative impact on children’s health and education.

Children are more vulnerable to heat-related events such as lightheadedness, fainting, coma or even death in rare cases.

Based on data extrapolated from the Healthcare Cost and Utilization Project’s Kids’ Inpatient Database , for each 1 degree Fahrenheit increase between May and September, the number of emergency department visits at U.S. children’s hospitals could increase by 113 visits per day.

“When exposed to higher temperatures, children have more difficulty concentrating and learning in the classroom,” Martinich said.

Studies show a 4% to 7% reduction in academic achievement associated with temperature increases of 2 to 4 degrees Celsius. This reduction translates to decreased future income for graduating students, which could be as much as $18.3 billion.

While installing air conditioning in educational facilities can help, this may not be an option for economically disadvantaged schools.

Stable housing is also a critical factor in children’s health and development. Increasing frequency of flooding due to the rising sea levels places children in coastal cities at high risk for temporary or permanent displacement from their homes.

The EPA estimates that if we do not adapt to the increased flooding risk, 17.2 million children, or 23% of all children in the U.S, are at risk for housing displacement. Children are also at risk of drowning, disease, and post-traumatic stress disorder from flooding events.

“Under each different level of future rising sea level there’s a whole new population that has been exposed [to flooding] in some parts of the country,” said Martinich.

Playing outdoors is crucial for children’s mental and physical development, however, the effects of climate change will significantly limit their ability to be outside. Warm seasons are getting longer, which leads to increased duration and severity of pollen allergies. Prolonged exposure to pollen has been associated with higher rates of asthma, eczema, hay fever, and even ADHD, or attention-deficit/hyperactivity disorder.

Air quality has also sharply decreased due to rising pollution, increasing temperature and wildfires. Infants and children have developing lungs and are more sensitive to toxic exposures than adults. Chronic exposure to pollution is also linked with cardiovascular disease and poor lung function in adulthood. Babies born to mothers exposed to severe air pollution are at risk of being born early or with low birth weight, which can lead to lifelong challenges with growth and development.

The EPA report does not say parents should not let their kids go outside, according to Martinich.

“We’re trying to empower caregivers and parents to be more aware of the risks,” he said, “just like you tell your kids about being careful when crossing the street.”

Parents can monitor daily air quality reports on AirNow.gov, which can be important for kids with asthma. The CDC has tips and resources on preventing toxic exposures for kids.

Similar to the findings of the State of the Air report released last week by the American Lung Association, communities of color face a disproportionate risk of impact. For these communities, the EPA report confirmed much of what they already know.

“It’s alarming, but it’s not surprising,” Courtney Hanson, deputy director of People for Community Recovery, an environmental justice organization on the South Side of Chicago, told ABC News. “[People for Community Recovery] has been advocating and raising the alarm bells about these issues for decades.”

The EPA report represents a key step in political advocacy, according to Gabrielle Browning, director and co-founder of Mom’s Clean Air Force.

“We are really excited about this report because it is the culmination of messaging on the vulnerability of children to climate change,” Browning told ABC News. “For the first time really in history, we have a lot of opportunities to get some things across the finish line.”

Parents can get involved in several ways, experts say.

“[Future generations of children] are going to inherit the world that we’re giving them,” said Martinich. “Let’s give them a safer future. That’s what this report is trying to inform.”

Browning suggests signing a petition that will be delivered to Congress, or calling the local school board to discuss current plans for sustainability.

“Doing something means that you can look your children in the eyes in a decade and say, ‘Yeah I did what I could do. We really tried hard,'” Browning said.

Hanson emphasized community engagement. “Visit the frontline neighborhoods in the city,” she said. “Learning about what’s going on in your own backyard … tends to be very impactful.”

Nisarg Bakshi, D.O., is a pediatrics resident at University of Chicago Comer Children’s Hospital and a member of the ABC News Medical Unit.

Copyright © 2023, ABC Audio. All rights reserved.

New report reveals popular diets rank lower for heart health

New report reveals popular diets rank lower for heart health
New report reveals popular diets rank lower for heart health
lacaosa/Getty Images

(NEW YORK) — The American Heart Association released a report Thursday that ranked the top 10 diets according to their guidelines for heart-healthy eating. Researchers found that some of the most popular diets – like keto and Paleo — ranked lower for heart health.

Nutritionist Maya Feller spoke to Good Morning America about the results of the study and what heart-healthy habits to keep in mind.

Feller said that researchers used the American Heart Association (AHA) criteria for heart-healthy eating patterns as the basis of the rating system, which includes nutrition requirements based on limited fat, saturated fats, cholesterol, trans fat or sodium.

“What they found was that these diets that were very low in carbohydrates like Atkins or diets that were very high in fat like keto actually scored lower,” Feller explained. “In the short term, there was some weight loss and there was some improvement in lipids as well as blood sugar. However, in the long term, it really can raise the risk for LDL [or] high cholesterol. That’s the bad cholesterol and that is a risk factor for heart disease.”

The very low carbohydrate diets and high-fat diets, like the ketogenic and Paleolithic diets, scored the lowest on the AHA scale.

“Restrictions on fruits, whole grains and legumes may result in reduced fiber intake. Additionally, these diets are high in fat without limiting saturated fat. Consuming high levels of saturated fat and low levels of fiber are both linked to the development of cardiovascular disease,” the AHA said in a statement.

The report also took other factors into consideration like diet flexibility, cultural relevance, personal preference and affordability.

The DASH diet, Mediterranean diet, pescatarian diet and vegetarian diet were among the top-scoring diets. The first two diets aid in managing hypertension, a known risk for heart disease.

“What we see when we’re looking at the top rated diets is there’s tons and tons of seafood. There’s legumes, there’s really nice carbohydrates, ones that have fiber,” Feller noted. “Across the board, we see these patterns of eating that are really rich in fruits, vegetables, lean proteins, as the way to think about bolstering your cardiovascular health.”

The AHA’s top-ranked diets often include vegetables, seafood, lean proteins, nuts, seeds and potassium-rich foods.

While people do not have to cut carbohydrates and fats completely out of their diet, Feller said that the best course of action is finding a pattern of eating that works best for the individual while just staying mindful.

“Carbohydrate literacy is key. We need carbohydrates as fuel and energy for our brain,” she said. “In terms of fat, replacing saturated and synthetic fats with mono and polyunsaturated fatty acids found in nuts, seeds and some fruits like olive and avocado can be a heart-healthy choice.”

Copyright © 2023, ABC Audio. All rights reserved.

Couple shares journey of going from infertility to adoption

Couple shares journey of going from infertility to adoption
Couple shares journey of going from infertility to adoption
Bella Weems-Lambert

(NEW YORK) — Bella Weems-Lambert and Dallin Lambert always knew they wanted to raise a family. They just hadn’t known that the journey — which would take them overseas and back — would be followed by hundreds of thousands of supporters online.

The duo share their struggle with infertility openly with their social media followers in hopes that it will make others feel better about their own stories.

Recently, after years of struggling with infertility and a series of unsuccessful in vitro fertilization treatments, the two shared an exciting update: They’re going to be parents through adoption.

“Adoption for us was never a last option. It was never like a last resort because of our infertility. We feel so strongly about adoption and we know that this is the right step for our family,” Weems-Lambert told “Good Morning America.” “But I feel like we had to go through those hard things to get to where we are now and I’m so grateful for our infertility to lead us to where we are right now.”

The couple married in 2017 and decided to take the first two years of their marriage to travel and “live up the married life” before trying to grow their family. After that, they decided they wanted to start a family, but after about a year of trying, they hadn’t had any success.

“I felt like I was so alone in that journey of trying and getting the negative pregnancy tests every month,” said Weems-Lambert, who said the couple decided to see a fertility specialist near their home in Gilbert, Arizona, in 2020.

Lambert said turning to a specialist felt “defeating” at first.

“It was really hard going and seeing that specialist because it’s kind of like it turned everything that you didn’t think was going to happen into a reality,” he said. “It was hard to especially watch Bella go through that.”

Weems-Lambert said she was diagnosed with diminished ovarian reserve and that the doctor had initially recommended a round of IVF, a well-known treatment for infertility, where a woman’s eggs and a man’s sperm are combined in a laboratory to create an embryo or embryos. If the embryo is viable, it is transferred into the woman’s uterus through her cervix.

Weems-Lambert said she wasn’t ready for IVF at the time and wanted to seek other treatment options.

“I am so young. I’m so healthy. I felt like I was in denial. I was like, ‘There’s no way that I have to do IVF,'” she said. “For six months, we did a bunch of different procedures. We did an IUI. We did some medicated cycles, we did injections…. And all were unsuccessful. It was really mentally draining and exhausting.”

The couple then decided it was time to try IVF. After a mutual friend connected them with an IVF doctor in Oman, they decided they were going to travel to the Middle East to “make an adventure” out of the treatment.

“We’re big travelers, we love traveling. So we felt like, let’s make light of the situation. Let’s go overseas,” said Weems-Lambert. “Let’s go and do IVF and try to make it fun.”

The couple also said the adventure spurred them to start sharing their infertility journey online.

“In the beginning, we weren’t very open with it. It was kind of scary to be vulnerable and talk about it with others,” said Lambert. “But then once we realized that we had the potential to help other couples going through it, we thought that it would be best to put it out there and start sharing it.”

Since then, the couple has amassed nearly 700,000 Instagram followers combined, and more than 1 million subscribers on YouTube.

“The more you share it, the more real it feels. And so, it was really hard at first starting to share our infertility journey or even saying the word infertility — like, it hurt to say out loud,” said Weems-Lambert. “But once we did share it, we were so happy because we realized that so many people struggle with infertility. I had no idea.”

According to a recent report from the World Health Organization, around 17.5% of the adult population — nearly 1 in 6 adults worldwide — experiences infertility.

Ultimately, after two trips to the Middle East and three unsuccessful rounds of IVF treatments, the couple decided on something that they always wanted to do: adopt.

“As we’re going through these infertility treatments, I always just kept thinking like, ‘It would be just so cool to adopt’ and I always had that on my heart,” said Weems-Lambert. “So we talked to some friends of ours and even family members who had adopted before, and every story was so beautiful.”

According to recent data from the Adoption and Foster Care Analysis and Reporting System within the U.S. Children’s Bureau, there were more than 114,000 children and youth waiting to be adopted in the United States in 2021 alone.

Prospective adoptive parents, like the Lamberts, who choose to utilize adoption agencies must typically undergo a strict review before an adoption is allowed to proceed, which can include verifying U.S. citizenship, meeting an age requirement and determining the “suitability” of each adoptive parent. Candidates undergo a criminal background check, fingerprinting and a home study, during which a professional will come to evaluate whether the home is suitable for the child.

After undergoing the evaluative process, Lambert and Weems-Lambert were adoption-certified on March 26. Now, the couple has connected with a few different agencies to help “match” expectant mothers with prospective adoptive parents.

“Every situation is different. You can [wait for a match] for a couple of years, or we’ve heard that it can be a couple of weeks or a couple of months,” said Lambert.

While they are waiting for the right match, the Lamberts are continuing to share their story online. Weems-Lambert said she even designed a necklace for her jewelry company, Think Goodness, and wrote a song for those who are also struggling with infertility.

For both, she shared the same message: You are not alone.

“If you’re struggling with infertility, you are not alone. It is so hard and it can be so isolating. And it’s totally valid to feel those heavy and sad days,” she said. “Find something that brings you hope and brings you that light that you need in your life.”

Copyright © 2023, ABC Audio. All rights reserved.

One-third of US teen girls seriously considered attempting suicide in 2021: CDC

One-third of US teen girls seriously considered attempting suicide in 2021: CDC
One-third of US teen girls seriously considered attempting suicide in 2021: CDC
Elva Etienne/Getty Images

(ATLANTA) — The number of teenage girls experiencing suicidal thoughts and behaviors increased during the second year of the pandemic, new federal data showed.

The percentage of high school female students who seriously considered attempting suicide rose from 24.1% to about one-third, or 30%, between 2019 and 2021, according to the latest results of the Youth Risk Behavior Survey, published Thursday by the Centers for Disease Control and Prevention.

The percentage of those who made a suicide plan increased from 19.9% to 23.6% and there was also an increase in suicide attempts from 11.0% to 13.3%, according to the CDC survey.

Differences were seen when it came to students’ ages, race/ethnicity or gender identity.

For example, 9th and 10th-grade girls were more likely to seriously consider attempting suicide than 12th-grade girls.

Ninth graders who were seriously considering suicide increased from 23.7% in 2019 to 30.7% in 2021 and 10th graders saw an increase from 23.6% to 33.6% over the same period. However, for 12th-grade girls, the risk went up from 24.0% in 2019 to 25.6% in 2021.

Freshman and sophomore high school girls were also more likely to make a suicide plan and attempt suicide compared to senior high school girls, according to the CDC.

“Because of the increased prevalence of suicidal thoughts and behaviors among female students, particularly for those in 9th- and 10th-grade, the importance of early prevention and intervention to prevent suicide is evident,” the authors wrote.

In 2021, Black students were nearly 1.5 times more likely than white female students to report having attempted suicide.

Compared to white female students, Hispanic female students had increased rates of suicide attempts requiring medical attention.

Additionally, LGBQ+ students had higher rates of reporting attempted suicide than heterosexual students, the CDC said.

Those identifying as lesbian or gay were found to have nearly 1.9 times higher rates, identifying as bisexual nearly 3.3 times higher rates, and identifying as questioning 1.5 times higher rates compared to heterosexual students.

Meanwhile, when it came to suicidal thoughts and behaviors among male students, percentages were relatively stable between 2019 and 2021.

The Youth Risk Behavior Survey is conducted every other year and surveys thousands of high school-age children from public and private schools between grades 9 and 12 across all 50 states and the District of Columbia.

Although suicide is the 11th leading cause of death overall in the United States, it is the third among U.S. high school students between the ages 14 and 18, accounting for one-fifth of all deaths among this age group, the report said.

The authors said the findings in the report are consistent with trends before the COVID-19 pandemic, but the rising rates of suicide risk among teen girls may be linked to how measures, such as social distancing and remote learning, may have increased students’ social isolation and anxiety.

Common risk factors for suicide include a history of depression and other mental illness, bullying, loss of relationships, and social isolation, according to the CDC.

The CDC team added that understanding why rates were stable among male students, even during an event such as the pandemic, “could yield insights into protective factors.”

“A comprehensive approach to suicide prevention, which reduces risk and supports youths at increased risk, provides support to those at risk and can ultimately save lives,” they wrote.

It comes after a report released earlier this year from the CDC showed teen girls were experiencing record-high levels of feelings of sadness and acts of violence.

Nearly three in five — or 57% — of girls reported feeling persistently sad or hopeless in 2021, up from 36% in 2011 and the highest levels seen in the past decade, the data found.

If you are struggling with thoughts of suicide or worried about a friend or loved one, call the Suicide & Crisis Lifeline at 988 for free, confidential emotional support 24 hours a day, seven days a week.

Copyright © 2023, ABC Audio. All rights reserved.

Some women opt to go abroad to battle high cost of egg freezing

Some women opt to go abroad to battle high cost of egg freezing
Some women opt to go abroad to battle high cost of egg freezing
fstop123/Getty Images

(NEW YORK) — Some women are willing to go the distance to preserve fertility — and make it more affordable.

After the age of 30, a woman’s fertility decreases every year, leading some women to turn to fertility preservation treatments, such as egg freezing, so they can delay starting a family while ensuring their chances of having one.

Egg freezing for fertility preservation is a process that has been around since the late 1990s, according to the National Institute of Health. The technique, which includes retrieving and subsequently freezing a woman’s viable eggs, was first used for young women with cancer who are at risk of infertility as a result of their treatment.

Now, it’s being offered to all women who are typically 38 and younger “who want to preserve the option of having healthy, genetically related children at a later date,” according to the National Institutes of Health.

However, egg freezing comes at a cost.

In the U.S. broadly, among the 180 clinics listed in Freeze Health’s Compare Clinics tool, the average cost for one cycle of egg freezing is, on average, approximately $12,450. That price tag doesn’t even include multiple cycles or annual storage fees, which can range between $600 to $800.

The high cost drives some women, like Spring Inés Peña, to go abroad in search of an insurance policy for their fertility that won’t break the bank.

“I figured, you know, Spain might be a nice little European relaxed vacation where I can go and do this very important procedure,” Peña told ABC News’ Good Morning America.

Peña, a 36-year-old from Los Angeles, traveled to Barcelona for her egg-freezing procedure. In Europe, the median cost of egg freezing is about 40% of the cost in the U.S. and in Spain, it’s even less expensive, according to data from Freeze Health.

Jennifer Lannon, the co-founder of Freeze Health, a free resource that allows women to compare clinics, said the price matters.

“It naturally makes sense that a lot of women have been catching on to this and whether they have friends or family abroad, they’re traveling for work, or they just want to take a trip somewhere else and save some money. They’re choosing to go to a cheaper location,” Lannon said.

According to Lannon, 1,000 women per month will click on Freeze Health’s guide to international egg freezing. She said the most popular countries are Mexico and Spain.

“If you’re looking to stay close to the U.S. and perhaps in the same time zone, maybe for work purposes, then Mexico tends to be the best option,” Lannon said. “If you’re looking to travel to Europe, then Spain, and specifically Barcelona, tends to be one of the hottest cities with the most options, the most reasonable prices, and also just does the most volume of egg freezing.”

The number of assisted reproductive technology cycles performed using embryos from frozen patient eggs or embryos increased from 32,180 in 2011 to 129,692 in 2020, according to the Centers for Disease Control and Prevention.

National data on success rates are scarce. One study found that the frozen egg live-birth rate is around 42%.

“It’s not a panacea. It is not a guarantee — the largest challenge is after the egg is frozen. It’s supposed to be a backup, that’s all it’s designed for,” said Dr. Karenne Fru, the medical director at OMA Fertility.

According to the CDC, there are several things to consider when opting for medical tourism. The risk of infectious disease and antibiotic resistance is higher in some countries and continuity of care may be challenging if you need follow-up care in the U.S. Importantly, you should be sure to look into your provider. Some countries’ requirements for maintaining licensure, credentialing and accreditation may be less than what would be required in the United States.

Aside from the physical challenges, freezing eggs abroad has its downsides, including language barriers. Ultimately, for Peña, the vacation and two cycles of egg freezing were worth the trip abroad.

“So with the vacation included and two cycles, since I did end up doing two, that ended up being what it would have cost for me to do it here in L.A., one cycle with no European vacation included,” she said. “So it was about half price.”

Copyright © 2023, ABC Audio. All rights reserved.

Popular diabetes drug Mounjaro could be FDA-approved for weight loss this year, company says

Popular diabetes drug Mounjaro could be FDA-approved for weight loss this year, company says
Popular diabetes drug Mounjaro could be FDA-approved for weight loss this year, company says
Sandy Huffaker for The Washington Post via Getty Images

(NEW YORK) — A popular drug currently approved to treat Type 2 diabetes could soon also be approved for weight loss.

Eli Lilly, the maker of the drug Mounjaro, said Thursday it expects the medication could be approved by the U.S. Food and Drug Administration for weight loss as early as the end of the year.

The company made the prediction on the timing of FDA approval as it announced top-line results of a Phase 3 study showing a nearly 16% overall weight loss over a 17-month period among people who have both Type 2 diabetes and obesity.

Prior studies among people with obesity without Type 2 diabetes have shown a weight loss within the range of 15% to 21%, depending on the dose of the medication given.

Eli Lilly is using the data from the Phase 3 study as part of its weight-loss approval request to the FDA. The company said Thursday it plans to complete the U.S. submission for the drug tirzepatide, sold under the brand name Mounjaro, in adults with obesity or overweight with weight-related comorbidities in the coming weeks.

Eli Lilly announced in October the FDA granted Fast Track designation to studying tirzepatide to treat obesity or excess weight with a secondary medical condition.

The FDA has not said when it would announce a decision about weight loss approval for tirzepatide.

Here are three questions answered about the medication:

1. How does Mounjaro work?

Mounjaro, approved by the FDA last year to treat Type 2 diabetes, is an injectable medication that patients take once per week.

Doctors will typically start out with a low dose of the injection and increase the dose after four weeks based on your body’s response.

The active ingredient in Mounjaro, tirzepatide, works by activating two naturally produced hormones in the body: glucagon-like peptide-1, known as GLP-1, and glucose-dependent insulinotropic polypeptide, or GIP.

The combination is said to slow the emptying of the stomach, making people feel full longer, and suppress appetite by slowing hunger signals in the brain.

In Type 2 diabetes, Mounjaro is recommended to be used along with “diet and exercise to improve blood sugar,” according to its website.

Mounjaro cannot be given to patients with certain medical conditions, including medullary thyroid cancer, pancreatitis, or gallstones.

Side effects can include severe nausea and constipation.

Its safety has not yet been established in minors.

2. How does Mounjaro differ from other drugs like Ozempic?

Ozempic and Wegovy are made from a different compound, called semaglutide.

These drugs, called GLP-1 RAs, help people produce insulin and lower the amount of sugar in the blood.

The FDA approved Ozempic in 2017 as a treatment for Type 2 diabetes alongside diet and exercise if other medications cannot control blood sugar levels well enough. Although Ozempic is not explicitly approved for chronic weight management, it can be prescribed off-label and used for people who are obese.

Wegovy is essentially the same injectable drug prescribed at a higher dosage. The FDA has specifically approved Wegovy for patients with severe obesity, or who are overweight and have one or more weight-associated conditions like high blood pressure or high cholesterol.

3. What changes if Mounjaro is FDA-approved for weight loss?

Formal FDA approval of Mounjaro for weight loss would have implications for insurance reimbursement, meaning people prescribed the medication for weight loss would be better able to have it covered by insurance.

The out-of-pocket cost for a drug like Mounjaro can run as high as $1,400 for a one-month supply.

If the FDA approves Mounjaro for weight loss, it also means Eli Lilly would be able to explicitly advertise Mounjaro as a weight loss drug.

Nearly 42% of all adults in the U.S. qualify as obese, defined as having a body mass index at or above 30, according to the Centers for Disease Control and Prevention.

Copyright © 2023, ABC Audio. All rights reserved.

‘Grey’s Anatomy’ star opens up about battle with postpartum anxiety, severe PMS disorder

‘Grey’s Anatomy’ star opens up about battle with postpartum anxiety, severe PMS disorder
‘Grey’s Anatomy’ star opens up about battle with postpartum anxiety, severe PMS disorder
Monica Shipper/Getty Images

(NEW YORK) — In Camilla Luddington’s role as Dr. Jo Wilson on Grey’s Anatomy, the actress was tasked with portraying a character who experienced mental health struggles, including a stay in a psychiatric facility.

Offscreen, Luddington is opening up about the mental health struggles she has experienced herself, including a battle with postpartum anxiety.

Luddington, a mom of two, said in a new interview with Wondermind , the Selena Gomez-backed mental fitness ecosystem, that she started therapy for the first time.

“I never felt like I needed to [undergo therapy], and then my daughter was born,” Luddington said. “I now look back and realize I had postpartum anxiety, which I didn’t know was a thing. I knew about postpartum depression, and I knew I didn’t have that, but I had so much anxiety.”

Luddington and her husband, actor Matt Alan, announced the birth of their daughter Hayden in April 2017. The couple announced the birth of their second child, a son named Lucas, in August 2020.

While some level of worrying is normal with a newborn, worries that turn irrational and incessant are signs of postpartum anxiety. Around 10% of postpartum women develop anxiety, according to the Anxiety and Depression Association of America.

Despite its prevalence, there is no category for it in the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders. Postpartum anxiety is most often grouped under postpartum depression, which affects about 1 in 7 women, according to the Anxiety and Depression Association of America.

Luddington said that for her, anxiety manifests in physical conditions. She said that by working with a therapist, she has learned tools to help her cope.

“I can feel myself physically getting anxious, which is a vicious circle [because] it gives me more anxiety to feel the anxiety,” Luddington said. “I feel anxiety, for example, in my feet. My feet start to tingle — that’s how I know I’m starting to get anxious. There are different parts of my body that I then start honing in on, like my heart racing.”

“[My therapist] tells me to find a place in my body that feels neutral, and, the funny thing is, I always think of my butt. My butt is never racing like my heart or tingling like my feet or hands,” she continued, laughing. “And actually honing in on that part of my body, or any part of [my] body that is not feeling the anxiety, is something that, in the moment, can kind of cool me down. … I know it [might] sound funny to some people, but figuring out an area of my body that is not manifesting that physical anxiety really helps me.”

After the birth of her second child in 2020, Luddington said she experienced another condition, premenstrual dysphoric disorder, which she said she did not know about before it happened to her.

“I never really had PMS growing up. … I hadn’t suffered from depression before [either], so I didn’t really understand what was going on. I just felt like there were times when, for a few days, I was just sad. Just depressed,” Luddington said. “My son was born during COVID in August 2020, so I kind of chalked it up to, ‘This is hard, this year’s hard, there are a lot of sad things happening in the world, and I’m just having one of those days.'”

Luddington said she began to notice that her bouts of irritability and depression coincided with the start of her menstrual cycle, which prompted her to go her doctor for help.

“When I went to go see my [doctor], I said, ‘I’m kind of noticing this happening every month,'” Luddington recalled. “I described my symptoms, and she said, ‘Well, that’s PMDD.’ And I had never even heard of that before.”

What to know about PMDD

Premenstrual dysphoric disorder affects as many as 5% of women of childbearing age, according to the Office on Women’s Health.

It is described as a condition similar to PMS but more severe in the symptoms it brings, including depression, thoughts of suicide, irritability, fatigue, anxiety and tension. Physical symptoms may include headaches, cramps, bloating, joint and muscle pain, insomnia and binge eating or food cravings.

PMDD happens in the week or two before a woman’s period starts, according to the Office on Women’s Health.

Exactly why PMDD occurs is not yet known, though it is suspected to have to do with hormonal changes. Serotonin levels, which also change during the menstrual cycle, may also play a role.

People who have a family history of depression, postpartum depression or other mood disorders may be more at risk for PMDD, according to Johns Hopkins Medicine.

When diagnosing PMDD, health care providers look for five or more PMDD symptoms, including a mood-related symptom, according to the Cleveland Clinic.

PMDD can be treated, which is why it is important to seek medical help.

Treatments can include everything from antidepressants and hormonal birth control to lifestyle changes like diet, exercise and stress-management tools, according to the Cleveland Clinic.

Luddington said that for her, starting on a prescription antidepressant was helpful, after meeting with a psychiatrist.

“I went on Zoloft for the first time this year, which I think is important to talk about because I feel like there’s still a stigma about medication,” Luddington said. “I was nervous about going on it because I was like, I’m an actress. Can I still be in touch with my feelings? Will I be able to cry on camera? Will I feel different? Will I seem out of it? [But] honestly, it has been super amazing for me, and this is the first time I’m talking about it.”

She added, “It definitely took away my PMDD, so I don’t have that dip every month. But then, also, it just helped any general anxiety I have. I feel like I’m a lot less anxious.”

If you are experiencing suicidal thoughts, substance use or other mental health crises, please call or text the new three digit code at 988. You will reach a trained crisis counselor for free, 24 hours a day, seven days a week. You can also go to 988lifeline.org.

Copyright © 2023, ABC Audio. All rights reserved.

FDA approves new drug for rare form of ALS

FDA approves new drug for rare form of ALS
FDA approves new drug for rare form of ALS
Sarah Silbiger/Getty Images

(WASHINGTON) — The U.S. Food and Drug Administration approved a new drug Tuesday to treat a rare form of amyotrophic lateral sclerosis, or ALS.

The drug Qalsody (tofersen) is expected to help people with a very specific mutation, SOD1, which applies to only 2% of the ALS population.

In a statement, the FDA said it estimates “there are fewer than 500 patients with SOD1-ALS in the United States.”

Among those who qualify, the drug has the potential to slow muscle degeneration by targeting SOD1 mRNA, or mRNA, genetic material that tells the body how to make proteins to reduce the protein being made.

Studies showed that the drug reduced plasma neurofilament light (NfL), a blood-based biomarker of axonal (nerve) injury and neurodegeneration, according to the FDA.

“Patients receiving Qalsody had nominally significant reductions in plasma NfL concentration at Week 28 compared to the placebo arm,” the FDA said in a statement.

The drug is given via a lumbar puncture — or a spinal injection — with three doses in 14-day intervals, followed by monthly dosing.

Researchers determined Qalsody to be safe with the most common side effects being pain, fatigue, joint and muscle pain and increased white blood cells in cerebrospinal fluid.

The drug was given conditional approval by the FDA under the fast track designation. Biogen, which makes the drug, will still need to complete additional and larger studies on its effectiveness.

It comes after the FDA approved another drug from Biogen, Aduhelm, in 2021 to treat Alzheimer’s disease despite a lack of evidence that it is effective.

ALS, also sometimes known as Lou Gehrig’s disease, is a neurodewngerative disease that affects nerve cells in the brain, leading to weakness and paralysis.

The disease often begins with patients experiencing muscle twitching and weakness in one arm or leg followed by having difficulty swallowing or slurring speech.

Patients’ conditions eventually decline to a point at which they are unable to move, speak, eat or even breathe on their own.

According to an 2017 estimate from the Centers for Disease Control and Prevention, about 32,000 people in the U.S. live with ALS.

There is no cure, but some already approved treatments may help. It is always fatal, according to the ALS Association.

Copyright © 2023, ABC Audio. All rights reserved.

Measles outbreak in American Samoa declared public health emergency

Measles outbreak in American Samoa declared public health emergency
Measles outbreak in American Samoa declared public health emergency
KATERYNA KON/SCIENCE PHOTO LIBRARY/Getty Images

(NEW YORK) — American Samoa has issued a public health emergency after an outbreak of measles has spread across the U.S. territory.

As of Tuesday, there has been one laboratory-confirmed case among an 8-year-old and 31 suspected and/or probable cases of the highly infectious disease, according to the Department of Health.

During a press briefing, Dr. Scott Anesi, the department’s lead epidemiologist, the suspected cases are all in children between ages 2 months old and 13 years old.

Anyone who tests positive for measles has been ordered to isolate for 21 days, while those who have or may have been exposed must quarantine for up to 21 days.

The emergency declaration, signed by Gov. Lemanu P.S. Mauga, is for 30 days and is set to expire Wednesday, May 24.

The outbreak has led the Department of Education in American Samoa, which serves 12,000 students, to close all schools until Friday, May 12.

Parents have been told that they can pick up their children’s virtual learning packers and any meals they are eligible for at their school sires through Friday.

This is not the first time there has been an outbreak in the area. According to a World Health Organization report, a 2019 outbreak swept the Pacific.

In American Samoa, there were 12 measles cases and no deaths reported. However, in the nation of Samoa, there were more than 5,700 cases and 83 deaths reported, most occurring in children under 5 years old.

The WHO and UNICEF said the outbreak came after measles, mumps, rubella (MMR) vaccine vaccination coverage fell from 74% to 34% between 2017 and 2018 after two infants died following immunization with improperly prepared vaccines, which led to vaccine hesitancy.

Measles is incredibly contagious, with the CDC saying every individual infected by the virus can spread it to up to 10 close contacts, if they are unprotected including not wearing a mask or not being vaccinated.

Complications from measles can be relatively benign, like rashes, or they can be much more severe, like viral sepsis, pneumonia or brain swelling.

The CDC says anybody who either had measles at some point in their life or who has received two doses of the MMR vaccine is protected against measles.

In the decade before the measles vaccine became available, an estimated 3 to 4 million people were infected every year, 48,000 were hospitalized and between 400 and 500 people died, according to the federal health agency.

One dose of the measles vaccine is 93% effective at preventing infection if exposed to the virus. Two doses are 97% effective.

Children are recommended to receive their first dose between 12 and 15 months old and their second dose between ages 4 and 6.

According to a report from the CDC published in January, during the 2021-22 school year, 88.3% of kindergartners in Ohio had received two doses of the MMR vaccine, less than the national average of 93%.

The American Samoa Department of Health says 89% of the students in daycares, elementary schools and high schools have received both doses of the MMR vaccines as of April 22.

The department shared a post on Facebook Tuesday of several clinics, halls and churches that will be offering the MMR vaccines for those aged 6 months and older.

Anesi said the goal for the territory is to achieve at least 95% and 100% among all school-age children.

“The main concern here is that those children that are one years old up to high school should be fully immunized as required by the DOE,” he said.

ABC News’ Eli Cahan contributed to this report.

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