Stock image of doctor and patient. (Westend61/Getty Images)
(NEW YORK) — As heart, kidney and metabolic problems progress to more advanced stages, a person’s risk of developing several cancers also rises sharply, a new study finds.
Cardiovascular-kidney-metabolic (CKM) syndrome is a disorder that occurs when heart disease, kidney problems and metabolic issues including obesity and diabetes all happen together, according to the American Heart Association.
About one in three U.S. adults have at least three risk factors for CKM syndrome, the AHA says.
Researchers used a claims database in Japan that included individuals with available health check-up data and insurance claims between April 2014 and August 2023.
People diagnosed with stage 3 CKM syndrome at the start of the study were 25% more likely to be diagnosed with one of 16 different cancers four years later in comparison to those with early CKM syndrome, according to the study published Monday in the journal Circulation.
Those who were diagnosed with stage 4 CKM syndrome had a 30% increased likelihood of having a cancer diagnosis four years later. Those diagnosed with stage 1 or stage 2 of the condition had a less than 5% chance of cancer diagnosis in four years.
“The study findings suggest that it is important to consider not only cardiovascular disease risk, but also cancer risk in people with CKM syndrome,” Dr. Hidehiro Kaneko, the study’s lead author and associate professor in the department of cardiovascular medicine at the University of Tokyo in Japan, said in a press release.
The study results accounted for age, gender and lifestyle factors including smoking, alcohol use and weight.
Individual symptoms such as high blood pressure are often used to determine certain cancer risks, but this study used a more patient-centered classification such as CKM syndrome staging as a predictor for certain cancers, according to the authors.
“CKM syndrome represents a complex interplay among the cardiovascular, kidney and metabolic systems, where dysfunction in one area may trigger or exacerbate dysfunction in others,” Kaneko said.
“Dysfunction in each of these systems is independently associated with cancer risk due to shared risk factors,” he continued. “This study suggests that the accumulation of risk factors within the framework of CKM syndrome may contribute to the development of various types of cancer.”
Because the study is a retrospective observational study, meaning it analyzes existing data, it can only speak to association between CKM syndrome and certain cancers, not causality.
Additionally, because the study was conducted in Japan, which has a very homogenous population, further research would be needed to replicate the results among the U.S. population, which is more diverse.
FBI personnel walk towards the house connected to Cole Tomas Allen, the shooting suspect at the White House Correspondents’ Dinner, in Torrance, CA on Saturday night, April 25, 2026. (Robbin Goddard / Los Angeles Times via Getty Images)
(WASHINGTON) — Cole Allen, the suspect in the shooting at the White House Correspondents’ Association Dinner on Saturday night, is expected to be arraigned in U.S. District Court on Monday.
Allen, 31, of Torrance, California, is a trained mechanical engineer working as a tutor who traveled across the country to perpetrate “as much damage as he could,” sources and officials said.
Local authorities said the suspect was tackled by law enforcement after gunfire inside the Washington Hilton, where thousands of journalists as well as President Donald Trump and members of his Cabinet were gathered for the annual event.
Allen was detained near the main magnetometer area for the event, with surveillance video showing the suspect running past security officials. Interim D.C. Metropolitan Police Department Chief Jeffrey Carroll told reporters that the suspect was armed with a shotgun, a handgun and multiple knives. Carroll said the preliminary information is that he was a “lone actor.”
Law enforcement officials briefed on the investigation said that Allen was declining to answer questions but allegedly made some non-specific reference to targeting administration officials.
A Secret Service member was shot during the incident but the bullet hit the agent’s protective vest, Trump said after the incident. The president said he spoke with the agent and he was in good spirits.
Shortly before the White House press briefing, Trump posted a video showing agents subduing the suspect, who he said “charged a security checkpoint armed with many weapons.”
Law enforcement officials said that Allen is believed to have booked a room in the Washington Hilton, where the dinner took place, in early April.
Investigators believe the suspect arrived in Washington by train, Acting Attorney General Todd Blanche said on Sunday during an interview on ABC News’ “This Week” with anchor George Stephanopoulos.
“We believe he traveled by train from Los Angeles to Chicago and then to Washington, D.C.,” Blanche said.
U.S. Attorney for D.C. Jeanine Pirro told reporters Saturday night, “It is clear, based upon what we know so far, that this individual was intent on doing as much harm and as much damage as he could.”
Pirro said the suspect was being charged with using a firearm during a crime of violence and assault on a federal officer using a dangerous weapon. She said additional charges could follow.
Allen is a trained mechanical engineer working as a tutor, according to a LinkedIn page connected to him.
According to his LinkedIn profile, Allen graduated in 2017 from CalTech, where he listed memberships in the school’s Christian Fellowship and Nerf Club. He graduated with a degree in mechanical engineering before earning a master’s degree from Cal State-Dominguez Hills in 2025, the profile said.
Allen characterized himself on LinkedIn as an “Indie Game Developer” who created a video game he described as “a skill-based, non-violent asymmetrical fighting game loosely derived from a chemistry model that is itself loosely based on reality,” according to the game’s Steam page.
Allen’s current employer, C2 Education, named Allen its “Teacher of the Month” in 2024, according to a post on LinkedIn. The tutoring company said in a statement that they were cooperating “fully” with law enforcement and denounced the “horrifying incident” at the dinner, but omitted in its statement details of Allen’s work history.
A group of high school students who were tutored by Allen shared a statement late Sunday describing Allen as “generally very intelligent” and “normal and friendly.”
Allen is not registered with any political party; his voter registration in Los Angeles County lists him as “no party preference,” according to voter registration records viewed by ABC News.
A Secret Service after-action review examining the security and possible lapses is already underway, according to officials briefed on internal procedures at the agency. The review is being conducted as a matter of standard procedure, which dictates that such a probe must be done whenever there is an “attack on a protectee.”
The review will go step-by-step through security planning and preparation, the deployment and assignment of personnel, as well as what occurred once the suspect rushed the Secret Service checkpoint. The Secret Service declined to comment on the after-action review.
ABC News’ Lauren Minore, Luke Barr, Nicholas Kerr, Ivan Pereira, Aaron Katersky, Josh Margolin, John Santucci, Michelle Stoddart, Lucien Bruggeman, Oren Oppenheim, Katherine Faulders and Peter Charalambous contributed to this report.
The US Supreme Court in Washington, DC, US, on Monday, April 20, 2026. (Graeme Sloan/Bloomberg via Getty Images)
(WASHINGTON) — For generations, cops have obtained warrants to lawfully seek information from a specific suspect in a crime.
The Supreme Court on Monday is considering whether investigators can also use so-called “geofence warrants” to do the reverse — scanning cell phone data of thousands of innocent individuals in hopes of finding a suspect to apprehend.
The landmark case is the first time the justices will consider whether the controversial practice of digital dragnets, which have grown in popularity among law enforcement with advances in technology, violate constitutional protections against unreasonable searches.
Critics say the warrants intrude on Americans’ reasonable expectation of privacy by compelling service providers to turn over broad swaths of user location history and time stamps within a specified area over a specified timeframe.
Advocates for geofence warrants call them a critical tool that will help police more quickly solve crimes, in turn making communities safer. They also emphasize that most cellphone users knowingly transmit location data to third-party tech companies already.
The petitioner in the case, Okello Chatrie, was indicted on charges related to an armed robbery of a Virginia credit union in 2019 and wants key cellphone location evidence against him thrown out.
Authorities relied heavily on data obtained from Google under a geofence warrant that placed Chatrie’s cellphone within 150 meters of the bank during the crime.
The Trump administration, which is defending the law enforcement tool and Chatrie’s prosecution, argues that by sharing location information with apps and service providers like Google, a person forfeits any expectation of privacy.
A decision in the case — Chatrie v U.S. — is expected by the end of June.
Acting Attorney General Todd Blanche appears on ABC News’ “This Week” on April 26, 2026. (ABC News)
(WASHINGTON) — Acting Attorney General Todd Blanche said Sunday that “the system worked” and kept President Donald Trump and other leaders safe from a shooting outside of the White House Correspondents’ Association Dinner on Saturday night that they were attending.
“The system worked; law enforcement and the Secret Service protected all of us. The man barely got past the perimeter. And so when you have a perimeter designed to keep people safe, like President Trump, and it works — that’s something that should be applauded,” Blanche told “This Week” anchor George Stephanopoulos when asked about the fact that the president and many members of the presidential line of succession were there.
“Secondly, as President Trump said, we are not going to stop doing what we’re doing. We’re not going to stop living; we’re not going to stop being out there,” Blanche added. “President Trump is going to continue communicating with the American people in public, and the fact that the vice president and other leadership were there last night in one room, is why we had such a robust security [operation] surrounding the place, inside the place, and it’s why we are all safe.”
Blanche spoke to Stephanopoulos the morning after a shooting incident outside the dinner.
The incident took place near the main magnetometer screening area at the event, according to the Secret Service. A suspect, whom law enforcement sources identified to ABC News as Cole Allen of Torrance, California, is in custody, officials said.
Blanche said the suspect was likely acting alone, although investigations are ongoing, and that “we believe that he traveled by train from Los Angeles to Chicago and then Chicago to Washington, D.C.”
Asked by Stephanopoulos how the suspect may have gotten a firearm into the hotel, Blanche replied, “It’s a good question. And listen, I’m not sure. It appears that he checked in on the 24th [of April] to the hotel, and we’re still looking at video surveillance and footage of where he walked and how he got in and how those firearms got in, but at the end of the day, I expect we’ll have a lot more about that in the coming days.”
(WASHINGTON) — President Donald Trump, first lady Melania Trump and other dignitaries were removed by security after an shooting incident outside the White House Correspondents’ Association Dinner in Washington, D.C., on Saturday night.
The incident took place near the main magnetometer screening area at the White House Correspondents’ Dinner, according to the Secret Service.
Trump and the other dignitaries who were evacuated were safe, according to the Secret Service. The Secret Service and the president said that a suspect has been apprehended.
Law enforcement is continuing to conduct the investigation.
This was the first correspondents’ dinner that Trump attended as president. He was scheduled to speak.
Other dignitaries who were escorted out included House Speaker Mike Johnson, and Vice President JD Vance.
Trump praised the Secret Service for their work.
“Quite an evening in D.C. Secret Service and Law Enforcement did a fantastic job. They acted quickly and bravely,” he said in a social media post.
Trump added the he “recommended that we “LET THE SHOW GO ON” but, will entirely be guided by Law Enforcement.”
“They will make a decision shortly. Regardless of that decision, the evening will be much different than planned, and we’ll just, plain, have to do it again,” he said.
White House Correspondents’ Association President Weijia Jiang told the crowd at the Washington Hilton ballroom that the program would continue at some point.
This is a developing story. Please check back for updates.
(CHICAGO) — Two police officers were shot at a hospital in Chicago on Saturday morning and one was in critical condition as the medical facility went on lockdown, local officials said.
The shooting was reported at around 11:00 a.m. local time at Endeavor Health Swedish Hospital, according to the hospital.
The unidentified suspect is now in custody, according to Alderperson Andre Vasquez of Chicago’s 40th Ward.
“Please shelter in place if you are in the surrounding area or avoid the area,” he said in a social media post
Vasquez said that one of the officers was in critical condition.
The hospital said there was no “active threat” within the hospital and patients and staff are safe.
“The campus is currently closed while law enforcement leads their investigation,” the hospital said.
This is a developing story. Please check back for updates.
Severe weather outlook for Saturday, April 25, 2026. (ABC News)
(NEW YORK) — A severe weather threat is shifting back to parts of Kansas and Oklahoma on Saturday after damaging winds, hail and tornadoes impacted the region over the past week.
A level 4 of 5 “moderate risk” has been added for southeast Oklahoma, including Ada and McAlester, for the potential for very large hail (larger than baseballs), strong tornadoes, and damaging winds.
A level 3 of 5 “enhanced risk” is up for northeastern Oklahoma and far eastern Arkansas, including Oklahoma City, Tulsa, Broken Bow and Enid, in Oklahoma, and Fort Smith, Arkansas.
Damaging winds and very large hail are the primary threats with these storms, but a few tornadoes, some potentially strong, cannot be ruled out with these storms.
This will be a later day event, with storms not likely to begin firing off until after at least 3:00 p.m. CT. Once storms get going, the atmosphere will be very favorable for discrete storms to intensify across eastern Oklahoma going into the evening hours.
Storms will continue to fire off during the evening up to just after sunset and will continue through the overnight hours across eastern Oklahoma, far northeast Texas and western Arkansas.
Beginning Sunday, a potent storm system will form southeast of the Rockies and swing northeast across the Plains, bringing more severe weather to the Plains on Sunday before the severe weather threat spreads northeast and stretches into the Midwest on Monday.
Almost 50 million Americans will be on alert for severe storms on Sunday or Monday – almost 8 million for Sunday, and almost 40 million for Monday.
For Sunday, a level 3 of 5 “enhanced risk” is up for much of Kansas as well as portions of western Missouri, including Wichita and Kansas City. Tornadoes, some being strong, as well as damaging winds and large hail are all possible with storms in this area.
A level 2 of 5 “slight risk” is also up for parts of northern Texas, northwestern Arkansas, western Missouri, far southwest Iowa, southern Nebraska, most of Oklahoma and much of the remaining areas of Kansas.
Like Saturday, severe storms will likely not begin firing off until the late afternoon. When storms do get going though during the evening, the atmosphere will be favorable for discrete thunderstorms to grow and intensify, producing tornadoes (some possibly strong), damaging winds and large hail.
For Monday, the severe weather threat spreads northeast and stretches from the lower Mississippi River valley up to the Midwest for Monday. A level 3 of 5 “enhanced risk” is up for cities like St. Louis; Cedar Rapids, Iowa; Jonesboro, Arkansas; Evansville, Indiana; Paducah, Kentucky; and Rockford, Illinois.
A level 2 of 5 “slight risk” is up for cities like Memphis; Louisville, Kentucky; Chicago; South Bend, Indiana; Milwaukee, Wisconsin; and Mason City, IIowa.
While there is some uncertainty in exact timing and setup with Monday’s storms, the potential for tornadoes with some being strong, as well as widespread damaging wind gusts, large hail, and spotty flash flooding is increasing for Monday for these areas.
With any discrete supercell thunderstorms that form and maintain themselves in this atmosphere, the “tornadic potential could maximize, with a few long track, particularly damaging tornadoes possible,” according to the NWS Storm Prediction Center.
This will likely be a late afternoon and evening setup regardless, with discrete storms or clusters of storms tracking in a line from Milwaukee and Chicago down to St. Louis and into northern Arkansas around the evening commute on Monday.
These storms will sweep east into the overnight hours, with Indianapolis; Paducah, Kentucky; and Memphis likely seeing storms later in the evening.
This storm system will also bring heavy rain to the central U.S., with some of it possibly falling in a short time with the heaviest storms. Because of this, isolated flash flooding is possible with these storms into the new week.
Heavy rain will also come to the Great Lakes on Monday, which could reinvigorate the flood risk given how saturated the ground still is from the historic rainfall from a few weeks ago combined with rapid snowmelt.
For Tuesday, we can see the severe weather threat shift to parts of the South as this potent system continues to move east. Places like Memphis; Little Rock, Arkansas; Tyler, Texas; Shreveport, Louisiana; and Jackson, Mississippi, will have to watch for potential severe weather later in the day.
Some showers, humidity in the Southeast The drought in the Southeast continues to worsen as two wildfires continue to burn in southeast Georgia.
Some rounds of rain and possibly isolated thunderstorms will move into the region later today and late Monday into Tuesday, with each round bringing around 0.5 to 1 inch of rain.
The rain will not tame the wildfires alone, especially if it doesn’t fall directly where the fires are. If there are any isolated thunderstorms, there is the chance that lightning could ignite additional wildfires in the already dry region.
However, the increased humidities and any rain that does fall on the fires this weekend into early next week will help with controlling ongoing fires and quickly manage any new fires if any should occur.
The rain will not make much of a dent on the drought situation across the region. For example, Georgia needs between 12 and 18 inches of rainfall to end the current drought.
The two notable fires in southeast Georgia, the Pineland Road Fire and the Highway 82 Brantley County Fire, continue to burn.
Meanwhile, the fire threat will be in the southern High Plains this weekend. Parts of Arizona, New Mexico, Colorado, as well as the panhandles of Texas and Oklahoma are under fire weather alerts this weekend.
In these photos released by the University of South Florida Police Department, Zamil Limon and Nahida Bristy are shown. (University of South Florida Police Department)
(TAMPA, Fla.) — The remains of one of the two missing University of South Florida doctoral students were discovered by investigators Friday and his roommate was arrested, authorities said.
Hisham Abugharbieh, 26, has now been charged with two counts of first-degree murder with a weapon in the deaths of Zamil Limon and Nahida Bristy, the Hillsborough County Sheriff’s Office announced on Saturday.
Investigators found the remains of Limon on the Howard Frankland Bridge in Tampa Friday morning, Joseph Maurer, of the Hillsborough County Sheriff’s Office, told reporters Friday.
The search for Bristy continues, the office said.
Investigators have been searching for Limon and fellow USF doctoral student Bristy since they went missing on April 16.
“We are still actively searching for Nahida,” he told reporters during a news conference Friday.
Maurer said investigators received a 911 call for a domestic violence disturbance around 9 a.m. Friday at a residence where Limon’s roommate, Abugharbieh, had barricaded himself.
Abugharbieh was previously interviewed by police during their investigation into the disappearances, Mauer said.
Following a brief standoff, the suspect surrendered, Maurer said. He was seen exiting the home with nothing but a towel wrapped around his waist.
Abugharbieh was initially charged with unlawfully holding or move a dead human body in unapproved conditions, failure to report a death to the medical examiner or law enforcement (intent to conceal), tampering with physical evidence, false imprisonment and battery, the sheriff’s office said.
The suspect is not a current USF student or employee, school officials said.
Abugharbieh will have his first court appearance on Saturday morning.
USF President Moez Limayem said in a statement Friday that there is “no ongoing threat to the safety of the university community.” He expressed “deep sadness” over Limon’s death and prayed for Bristy’s “safe return.”
The cause of Limon’s death is being determined, Maurer said. He had no further details about Bristy’s condition.
Marine and dive teams were searching near the Howard Frankland Bridge for Bristy, the sheriff’s office said.
Limon and Bristy, both 27, were last seen at separate locations in the Tampa area on April 16, according to the USF Police Department.
On Thursday, officials received new information to warrant upgrading their status from missing to endangered, which indicates they are at risk of physical injury or death, the Hillsborough County Sheriff’s Office said.
The sheriff did not provide any more details about the investigation or search efforts.
Limon and Bristy are friends, and a mutual acquaintance reported them missing, campus police said.
Limon was last seen at his Tampa residence at approximately 9 a.m. on April 16, according to police.
He had attended the university since fall 2024 to study geography and environmental science and policy, school officials said.
Bristy was last seen at the USF Tampa campus at the Natural & Environmental Sciences Building at approximately 10 a.m. on April 16, police said.
She has attended the university since fall 2025 to study chemical engineering, school officials said.
Anyone with information on her whereabouts is urged to call the University of South Florida Police Department at 813-974-2628.
-ABC News’ Meredith Deliso contributed to this report.
President Trump Signs Executive Order At The White House (Photo by Tasos Katopodis/Getty Images)
(WASHINGTON) — A federal judge is raising concerns about whether Donald Trump’s attempt to sue the IRS for $10 billion can proceed, signaling she could throw out the case because the president oversees the government entities he is suing.
Judge Kathleen Williams raised the issue in an order on Friday denying a request to delay the case amid possible settlement talks.
She noted that Trump and the defendants — the Treasury Department and IRS — may not be “sufficiently adverse” to one another for the case to proceed.
“Moreover, although President Trump avers that he is bringing this lawsuit in his personal capacity, he is the sitting president and his named adversaries are entities whose decisions are subject to his direction. Indeed, President Trump’s own remarks about this matter acknowledge the unique dynamic of this litigation,” she wrote.
Williams ordered both Trump’s lawyers and the Department of Justice to submit briefs about why the case should proceed and set a hearing for next month. For the case to proceed, Trump’s lawyers and the DOJ need to establish that the lawsuit is “a dispute between parties who face each other in an adversary proceeding.”
“Typically, adverseness is found in a situation where one party is asserting its right and the other party is resisting,” she noted.
But with Trump in charge of the very government entities he is suing, Williams noted that the required adverse relationship between the parties may not exist. She added that Trump has signed multiple executive orders tightening the president’s control over the executive agencies like the Department of Justice.
“One such employee of the executive branch, the Attorney General, has a statutory obligation to defend the IRS when it is hailed into court, but then is ostensibly required by executive mandate to adhere to the President’s opinion on a matter of law in such a case. This raises questions over whether the Parties here are truly antagonistic to each other,” Williams noted.
Trump, his sons Eric Trump and Donald Trump Jr., and the Trump Organization filed a lawsuit against the Internal Revenue Service and Treasury Department in January related to the unauthorized disclosure of tax information during Trump’s first term.
A government contractor with the IRS pleaded guilty in 2023 to stealing the tax information of Donald Trump and other wealthy Americans and leaking it to media outlets in 2019 and 2020.
In a court filing last week, lawyers for the Trumps said that they were “in discussions” with the Department of Justice to potentially resolve the lawsuit and requested a deadline extension so they can “engage in discussions designed to resolve this matter and to avoid protracted litigation.”
The filing said both sides agreed to the 90-day extension. The Department of Justice had not yet responded to the lawsuit and faced an impending deadline this month.
The Trumps, in the suit, argued that the IRS and Treasury Department should have had “appropriate technical, employee screening, security, and monitoring” to prevent the theft of tax information.
A group of former government officials last month filed an amicus brief with the court to raise concerns about the ethics of the president suing his own government for billions.
“This case is extraordinary because the President controls both sides of the litigation, which raises the prospect of collusive litigation tactics,” the amicus filing said. “To treat this case like business as usual would threaten the integrity of the justice system and the important taxpayer and privacy protections at the heart of this case.”
A Border Patrol Vehicle Stands Watch at the Mexican American Border Wall Outside of El Paso Texas. (Photo by Joey Ingelhart/E+)
An appeals court on Friday affirmed a district court’s ruling that an executive order invoked by President Donald Trump to suspend immigration asylum claims is unlawful.
In a divided 2-1 ruling, the Court of Appeals for the District of Columbia Circuit affirmed a court order saying the Immigration and Nationality Act allows migrants who cross the southern border apply for asylum.
“The INA does not allow the President to remove Plaintiffs under summary removal procedures of his own making,” the court wrote. “Nor does it allow the Executive to suspend Plaintiffs’ right to apply for asylum, deny Plaintiffs’ access to withholding of removal under the INA, or curtail mandatory procedures for adjudicating Plaintiffs’ Convention Against Torture claims.”
On Day 1 of his second term in office, President Trump issued an executive order he called “Guaranteeing the States Protection Against Invasion,” which aimed to block immigrants from seeking asylum and other forms of relief once they enter the United States and to allow for their swift removal from the country.
Friday’s ruling means that migrants who make it to U.S. soil, whether at a legal port of entry or in between, can legally seek asylum as has been allowed in previous administrations.
The Trump administration will likely appeal the decision, which could set up a possible showdown at the Supreme Court.
“This decision will potentially save the lives of thousands of people fleeing grave danger who were denied even a hearing under the Trump administration’s horrific asylum ban,” said ACLU attorney Lee Gelernt, who argued the appeal.
A spokesperson for the Department of Homeland Security said they “strongly disagree” with the ruling and that “this will not be the last word on this matter.”
“America’s asylum system was never intended to be used as a de facto amnesty program or a catch-all, get-out-of-deportation-free card. President Trump’s top priority remains the screening and vetting of all aliens seeking to come, live, or work in the United States,” the spokesperson said. “We will use all of the tools in our toolbox to ensure that the integrity of our legal immigration system is upheld, fraud is uncovered and expeditiously addressed, and illegal aliens are removed from the country.”
